Abstract: A method of determining a position offset includes receiving a first detection result from a first pixel of a plurality of pixels of a radiation detector, wherein the plurality of pixels are disposed on an incident side of the radiation detector on which an anti-scatter grid (ASG) is arranged, the plurality of pixels being aligned in at least a channel direction; receiving a second detection result from a second pixel of the plurality of pixels, wherein a septa of the ASG is arranged over a portion of the first pixel but is not arranged over any portion of the second pixel as viewed from the incident side of the radiation detector; estimating a positional offset of the septa of the ASG, based on the first detection result and the second detection result.

Abstract: An X-ray scanner system is provided. The system includes a photon-counting detector, a memory, and processing circuitry. The detector has a plurality of detector pixels in a channel direction. The memory stores a detector response forward model of the photon-counting detector. The detector response forward model is to be used during image reconstruction of an imaging object. The processing circuitry estimates an attenuation profile of the imaging object, determine, with respect to each of the plurality of detector pixels, a set of spatial weights, based on the estimated attenuation profile, and update, based on the determined set of spatial weights, the detector response forward model stored in the memory.

Abstract: A method for determining a model characterizing an output from a photon-counting detector (PCD) used in a computed tomography (CT) system is provided. The PCD has a plurality of pixels. The method includes constructing a PCD output model that has a plurality of model parameters including a first model parameter set. The first model parameter set is dependent on an incident count rate on the PCD, and dependent on a pixel position in the PCD. The method also includes receiving calibration data acquired by scanning a plurality of combinations of basis materials, under a plurality of incident count rates. The method further includes estimating the plurality of model parameters based on the received calibration data.

Abstract: An apparatus and a method for detection of defective pixels for a photon-counting detector-based computed tomography (CT) system is disclosed. In particular, the apparatus and the method disclosed herein, detect detector pixels that have intermittent behavior using on-the-fly defective pixel screening based on various criteria during an object scan. The defective pixels are discarded using a defective pixel map before image reconstruction.

Abstract: A method and a system for providing calibration for a polychromatic photon counting detector forward counting model. Measurements with multiple materials and known path lengths are used to calibrate the photon counting detector counting response of the forward model. The flux independent weighted bin response function is estimated using the expectation maximization method, and then used to estimate the pileup correction terms at plural tube voltage settings for each detector pixel. The beam hardening corrections are then applied to the measured projection data sinogram, and the corrected sinogram is reconstructed to the counting image at the selected single energy.

Abstract: A photon counting computed tomography (CT) method including receiving a first forward model including a set of first parameters and a set of second parameters corresponding to a plurality of materials and path lengths by scanning a slab at plural tube voltages and plural tube currents of an X-ray tube; evaluating an image quality of a material decomposition image reconstructed by the set of first parameters and the set of second parameters; and updating at least one second parameters from the set of second parameters if the image quality of the material decomposition image does not satisfy a predetermined threshold, wherein the updating is achieved by updating the at least one second parameter from the set of second parameters to an energy dependent parameter from a constant value.

Abstract: A method is provided for generating an attenuation map for PET image reconstruction. The method includes training a deep convolutional neural network (DCNN) model by minimizing a loss function between initial input image data and the attenuation map generated by a spectral CT scan as supervised data. Further, the method includes obtaining PET data from a scan of a subject and reconstructing a PET image from the PET data and an attenuation map output from the DCNN. The initial input image data can be from a conventional CT scan with or without beam-hardening correction or the input image data can be from a phantom, a simulation, or a SPECT image.

Abstract: A method and a system for providing calibration for a photon counting CT detector forward model for material decomposition. Various slabs of predetermined material and path lengths are placed in the photon counting CT detector and scanned using one or more stationary X-rays to obtain calibration data and parametrize the forward model.

Abstract: A method and a system for providing calibration for a photon counting detector forward model for material decomposition. The flux independent weighted bin response function is estimated using the expectation maximization method, and then used to estimate the pileup correction terms at each tube voltage setting for each detector pixel.

Abstract: A photon counting detector (PCD) apparatus includes a PCD array including a plurality of micro-pixels positioned in at least one of a channel direction and a row direction; and processing circuitry configured to: receive signals from each of the plurality of micro-pixels; configure the PCD array to include (a) a first micro-pixel area including a first group of plural micro-pixels of the plurality of micro-pixels and (b) a second micro-pixel area including a second group of plural micro-pixels of the plurality of micro-pixels, such that a portion of the first and second groups of plural micro-pixels overlap between the first and second groups; bin the signals from the first group of plural micro-pixels into a first virtual bin value; and bin the signals from the second group of plural micro-pixels into a second virtual bin value.

Abstract: A photon counting computed tomography (CT) method including, but not limited to, receiving a first forward model including a set of first parameters and a set of second parameters corresponding to a plurality of materials and path lengths by scanning a slab at plural tube voltages and plural tube currents of an X-ray tube; evaluating an image quality of a material decomposition image reconstructed by the set of first parameters and the set of second parameters; and updating at least one second parameters from the set of second parameters if the image quality of the material decomposition image does not satisfy a predetermined threshold, wherein the update of the at least one second parameter from the set of second parameters is achieved by updating the at least one second parameter from the set of second parameters to an energy dependent parameter from a constant value. Processing circuitry that is part of a photon counting computed tomography (CT) can implement the method.

Abstract: A method and apparatus for diagnosing and/or calibrating underperforming pixels in detectors in a small pixelated photon counting CT system utilizes a series of tests on image data acquired in-situ as part of a series of calibration scans in the CT system. Tests are performed on the acquired data to determine the existence of underperforming pixels within the detectors such that the information acquired by those pixels can be replaced by alternate data from surrounding pixels (e.g. by interpolation). The underperforming pixels are stored in “bad” pixel tables and may be specific to a type of image (e.g., spectral or counting) and a specific protocol.

Abstract: A method and a system for providing calibration for a polychromatic photon counting detector forward counting model. Measurements with multiple materials and known path lengths are used to calibrate the photon counting detector counting response of the forward model. The flux independent weighted bin response function is estimated using the expectation maximization method, and then used to estimate the pileup correction terms at plural tube voltage settings for each detector pixel. The beam hardening corrections are then applied to the measured projection data sinogram, and the corrected sinogram is reconstructed to the counting image at the selected single energy.

Abstract: A method and a system for providing calibration for a polychromatic photon counting detector forward counting model. Measurements with multiple materials and known path lengths are used to calibrate the photon counting detector counting response of the forward model. The flux independent weighted bin response function is estimated using the expectation maximization method, and then used to estimate the pileup correction terms at plural tube voltage settings for each detector pixel. The beam hardening corrections are then applied to the measured projection data sinogram, and the corrected sinogram is reconstructed to the counting image at the selected single energy.

Abstract: A method and a system for a two-step calibration method for the polychromatic semiconductor-based PCD forward counting model, to account for various pixel summing readout modes for imaging at different resolutions. The flux independent weighted bin response function is estimated using the expectation maximization method, and then used to estimate the pileup correction terms at plural tube voltage settings for each detector pixel. To correct the variation of the detector response due to different PCD sub-pixel summing schemes, the embodiments calibrate forward model parameters based on the various pixel readout modes.

Abstract: An apparatus, system and method for calibrating an x-ray apparatus including acquiring sinogram data by scanning a symmetrical phantom using a plurality of detector channels; generating mirror-copied sinogram data by mirror-copying at least one of first sinogram data and second sinogram data of the acquired sinogram data, wherein the first sinogram data and the second sinogram data are generated by dividing the sinogram data at a center detector channel of the plurality of detector channels; outputting a first reconstructed image by reconstructing the mirror-copied sinogram data; and determining a calibration parameter based on the first reconstructed image.

Abstract: A method and apparatus for diagnosing and/or calibrating underperforming pixels in detectors in a small pixelated photon counting CT system utilizes a series of tests on image data acquired in-situ as part of a series of calibration scans in the CT system. Tests are performed on the acquired data to determine the existence of underperforming pixels within the detectors such that the information acquired by those pixels can be replaced by alternate data from surrounding pixels (e.g. by interpolation). The underperforming pixels are stored in “bad” pixel tables and may be specific to a type of image (e.g., spectral or counting) and a specific protocol.

Abstract: A method and a system for providing calibration for a photon counting CT detector forward model for material decomposition. Various slabs of predetermined material and path lengths are placed in the photon counting CT detector and scanned using one or more stationary X-rays to obtain calibration data and parametrize the forward model.

Abstract: An apparatus, system and method for calibrating an x-ray apparatus including acquiring sinogram data by scanning a symmetrical phantom using a plurality of detector channels; generating mirror-copied sinogram data by mirror-copying at least one of first sinogram data and second sinogram data of the acquired sinogram data, wherein the first sinogram data and the second sinogram data are generated by dividing the sinogram data at a center detector channel of the plurality of detector channels; outputting a first reconstructed image by reconstructing the mirror-copied sinogram data; and determining a calibration parameter based on the first reconstructed image.

Abstract: A method and a system for providing calibration for a polychromatic photon counting detector forward counting model. Measurements with multiple materials and known path lengths are used to calibrate the photon counting detector counting response of the forward model. The flux independent weighted bin response function is estimated using the expectation maximization method, and then used to estimate the pileup correction terms at plural tube voltage settings for each detector pixel. The beam hardening corrections are then applied to the measured projection data sinogram, and the corrected sinogram is reconstructed to the counting image at the selected single energy.