Abstract: A method is provided for generating an attenuation map for PET image reconstruction. The method includes training a deep convolutional neural network (DCNN) model by minimizing a loss function between initial input image data and the attenuation map generated by a spectral CT scan as supervised data. Further, the method includes obtaining PET data from a scan of a subject and reconstructing a PET image from the PET data and an attenuation map output from the DCNN. The initial input image data can be from a conventional CT scan with or without beam-hardening correction or the input image data can be from a phantom, a simulation, or a SPECT image.

Abstract: A photon counting detector (PCD) apparatus includes a PCD array including a plurality of micro-pixels positioned in at least one of a channel direction and a row direction; and processing circuitry configured to: receive signals from each of the plurality of micro-pixels; configure the PCD array to include (a) a first micro-pixel area including a first group of plural micro-pixels of the plurality of micro-pixels and (b) a second micro-pixel area including a second group of plural micro-pixels of the plurality of micro-pixels, such that a portion of the first and second groups of plural micro-pixels overlap between the first and second groups; bin the signals from the first group of plural micro-pixels into a first virtual bin value; and bin the signals from the second group of plural micro-pixels into a second virtual bin value.

Abstract: A photon-counting imaging system is provided. The system includes a photon-counting detector and processing circuitry. The detector acquires, from an imaging object, projection data for a plurality of projection views. The detector has a plurality of detector pixels that are arranged in both a channel direction and a segment direction on a surface of the detector. The processing circuitry obtains the projection data acquired by the detector. The projection data includes first and second projection data. The processing circuitry processes, with a first energy bin setting, the first projection data, the first energy bin setting having m energy bins, and processes, with a second energy bin setting, the second projection data, the second energy bin setting having n energy bins, where n>m. The processing circuitry generates, based on the processed first projection data and the processed second projection data, a material decomposition image of the imaging object.

Abstract: A method for performing object scan data correction in an X-ray imaging system having a photon-counting detector is provided. The method includes acquiring calibration scan data from a calibration scan performed using a plurality of slabs, performing function fitting based on the acquired calibration scan data to generate a plurality of fitting functions corresponding to the plurality of slabs, each corresponding fitting function representing a relationship between a counting measurement detected with respect to one slab of the plurality of slabs and a tube current applied to the X-ray tube, establishing a calibration table based on the acquired calibration scan data, acquiring object scan data from an object scan performed on an imaging object, performing data correction for the acquired object scan data, based on the established calibration table and the generated plurality of fitting functions and reconstructing an image of the imaging object based on the performed data correction.

Abstract: A method of imaging includes analyzing a first image to detect objects in the first image and corresponding features of the objects; based on a detection result of a first object having a corresponding first object feature in the first image, selecting an action corresponding to the first object and the first object feature from a database; determining an updated set of scan parameters based on the selected action; and adjusting at least one of the table, the X-ray source, the X-ray detector, and the arm based on the updated set of scan parameters.

Abstract: A method for performing detector response correction in an X-ray imaging system having a photon-counting detector is disclosed. The method includes obtaining calibration data stored in a calibration data storage, which is generated during a calibration procedure performed with the X-ray imaging system at a first time. The method also includes acquiring air scan data generated through an air scan performed with the X-ray imaging system at a second time after the first time. The method further includes performing, with the X-ray imaging system, an object scan on an imaging object at a third time to generate object scan data. The third time is after the second time. The method further includes performing, using the generated object scan data, detector response correction based on the acquired air scan data and the obtained calibration data, and reconstructing, based on the performed detector response correction, an image of the imaging object.

Abstract: An apparatus and a method for detection of defective pixels for a photon-counting detector-based computed tomography (CT) system is disclosed. In particular, the apparatus and the method disclosed herein, detect detector pixels that have intermittent behavior using on-the-fly defective pixel screening based on various criteria during an object scan. The defective pixels are discarded using a defective pixel map before image reconstruction.

Abstract: An X-ray scanner system is provided. The system includes a photon-counting detector, a memory, and processing circuitry. The detector has a plurality of detector pixels in a channel direction. The memory stores a detector response forward model of the photon-counting detector. The detector response forward model is to be used during image reconstruction of an imaging object. The processing circuitry estimates an attenuation profile of the imaging object, determine, with respect to each of the plurality of detector pixels, a set of spatial weights, based on the estimated attenuation profile, and update, based on the determined set of spatial weights, the detector response forward model stored in the memory.

Abstract: A method of imaging includes analyzing a first image to detect objects in the first image and corresponding features of the objects; based on a detection result of a first object having a corresponding first object feature in the first image, selecting an action corresponding to the first object and the first object feature from a database; determining an updated set of scan parameters based on the selected action; and adjusting at least one of the table, the X-ray source, the X-ray detector, and the arm based on the updated set of scan parameters.

Abstract: A photon-counting imaging system is provided. The system includes a photon-counting detector and processing circuitry. The detector acquires, from an imaging object, projection data for a plurality of projection views. The detector has a plurality of detector pixels that are arranged in both a channel direction and a segment direction on a surface of the detector. The processing circuitry obtains the projection data acquired by the detector. The projection data includes first and second projection data. The processing circuitry processes, with a first energy bin setting, the first projection data, the first energy bin setting having m energy bins, and processes, with a second energy bin setting, the second projection data, the second energy bin setting having n energy bins, where n>m. The processing circuitry generates, based on the processed first projection data and the processed second projection data, a material decomposition image of the imaging object.

Abstract: A method of determining a position offset includes receiving a first detection result from a first pixel of a plurality of pixels of a radiation detector, wherein the plurality of pixels are disposed on an incident side of the radiation detector on which an anti-scatter grid (ASG) is arranged, the plurality of pixels being aligned in at least a channel direction; receiving a second detection result from a second pixel of the plurality of pixels, wherein a septa of the ASG is arranged over a portion of the first pixel but is not arranged over any portion of the second pixel as viewed from the incident side of the radiation detector; estimating a positional offset of the septa of the ASG, based on the first detection result and the second detection result.

Abstract: An X-ray scanner system is provided. The system includes a photon-counting detector, a memory, and processing circuitry. The detector has a plurality of detector pixels in a channel direction. The memory stores a detector response forward model of the photon-counting detector. The detector response forward model is to be used during image reconstruction of an imaging object. The processing circuitry estimates an attenuation profile of the imaging object, determine, with respect to each of the plurality of detector pixels, a set of spatial weights, based on the estimated attenuation profile, and update, based on the determined set of spatial weights, the detector response forward model stored in the memory.

Abstract: A method for determining a model characterizing an output from a photon-counting detector (PCD) used in a computed tomography (CT) system is provided. The PCD has a plurality of pixels. The method includes constructing a PCD output model that has a plurality of model parameters including a first model parameter set. The first model parameter set is dependent on an incident count rate on the PCD, and dependent on a pixel position in the PCD. The method also includes receiving calibration data acquired by scanning a plurality of combinations of basis materials, under a plurality of incident count rates. The method further includes estimating the plurality of model parameters based on the received calibration data.

Abstract: An apparatus and a method for detection of defective pixels for a photon-counting detector-based computed tomography (CT) system is disclosed. In particular, the apparatus and the method disclosed herein, detect detector pixels that have intermittent behavior using on-the-fly defective pixel screening based on various criteria during an object scan. The defective pixels are discarded using a defective pixel map before image reconstruction.

Abstract: A method and a system for providing calibration for a polychromatic photon counting detector forward counting model. Measurements with multiple materials and known path lengths are used to calibrate the photon counting detector counting response of the forward model. The flux independent weighted bin response function is estimated using the expectation maximization method, and then used to estimate the pileup correction terms at plural tube voltage settings for each detector pixel. The beam hardening corrections are then applied to the measured projection data sinogram, and the corrected sinogram is reconstructed to the counting image at the selected single energy.

Abstract: A photon counting computed tomography (CT) method including receiving a first forward model including a set of first parameters and a set of second parameters corresponding to a plurality of materials and path lengths by scanning a slab at plural tube voltages and plural tube currents of an X-ray tube; evaluating an image quality of a material decomposition image reconstructed by the set of first parameters and the set of second parameters; and updating at least one second parameters from the set of second parameters if the image quality of the material decomposition image does not satisfy a predetermined threshold, wherein the updating is achieved by updating the at least one second parameter from the set of second parameters to an energy dependent parameter from a constant value.

Abstract: A method is provided for generating an attenuation map for PET image reconstruction. The method includes training a deep convolutional neural network (DCNN) model by minimizing a loss function between initial input image data and the attenuation map generated by a spectral CT scan as supervised data. Further, the method includes obtaining PET data from a scan of a subject and reconstructing a PET image from the PET data and an attenuation map output from the DCNN. The initial input image data can be from a conventional CT scan with or without beam-hardening correction or the input image data can be from a phantom, a simulation, or a SPECT image.

Abstract: A method and a system for providing calibration for a photon counting CT detector forward model for material decomposition. Various slabs of predetermined material and path lengths are placed in the photon counting CT detector and scanned using one or more stationary X-rays to obtain calibration data and parametrize the forward model.

Abstract: A method and a system for providing calibration for a photon counting detector forward model for material decomposition. The flux independent weighted bin response function is estimated using the expectation maximization method, and then used to estimate the pileup correction terms at each tube voltage setting for each detector pixel.

Abstract: A photon counting detector (PCD) apparatus includes a PCD array including a plurality of micro-pixels positioned in at least one of a channel direction and a row direction; and processing circuitry configured to: receive signals from each of the plurality of micro-pixels; configure the PCD array to include (a) a first micro-pixel area including a first group of plural micro-pixels of the plurality of micro-pixels and (b) a second micro-pixel area including a second group of plural micro-pixels of the plurality of micro-pixels, such that a portion of the first and second groups of plural micro-pixels overlap between the first and second groups; bin the signals from the first group of plural micro-pixels into a first virtual bin value; and bin the signals from the second group of plural micro-pixels into a second virtual bin value.