Patents by Inventor Xiaojiang Hao

Xiaojiang Hao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compond for treatment or prevention of of obesity or diseases related to obesity, and application thereof
    Publication number: 20200385396
    Abstract: A compound for treatment or prevention of obesity or diseases related to obesity, and an application thereof. Specifically, provided are a compound as represented by formula I, or a pharmaceutically-acceptable salt thereof, and a pharmaceutical composition containing the compound. The compound has multiple functions and can be used for treatment or prevention of obesity or diseases related to obesity.
    Type: Application
    Filed: September 21, 2018
    Publication date: December 10, 2020
    Inventors: Yunfu ZHOU, Lin LI, Xiaojiang HAO, Duozhi CHEN
  • 15-oxospiramilactone derivatives, preparation method and uses thereof
    Patent number: 10112918
    Abstract: The invention relates to a derivative of 15-oxospiramilacton, particularly to a compound of Formula I or II, or an isomer, a solvate or a pharmaceutically acceptable salt thereof. The invention also relates to a pharmaceutical composition comprising the compound as pharmaceutically active ingredient, a method for preparing the same, and use thereof in manufacture of an anti-tumor agent. The derivative of 15-oxospiramilactone of the invention have an activity against multiple tumor cell lines, and the anti-tumor activity is positively correlated to an activity inhibiting the Wnt signaling pathway.
    Type: Grant
    Filed: April 21, 2014
    Date of Patent: October 30, 2018
    Assignees: Kunming Institute of Botany, The Chinese Academy of Sciences, The Key Laboratory of Chemistry for Natural Product of Guizhou Province and Chinese Academy of Science, Shanghai Institutes of Biological Sciences, CAS, Institute of Zoology, Chinese Academy of Sciences
    Inventors: Xiaojiang Hao, Chen Yan, Haiyang Liu, Lin Li, Xiaoli He, Quan Chen
  • Phenanthridine derivatives, preparation methods and uses thereof
    Patent number: 9682954
    Abstract: The present invention relates to the pharmaceutical field, in particular to a phenanthridine derivative as shown in general formula (1) a pharmaceutical composition comprising the derivative, its preparation method, and its uses in manufacture of a medicament for the prevention or treatment of a disease related to the activity of Wnt signaling pathway, hepatitis C and hepatitis B.
    Type: Grant
    Filed: February 28, 2014
    Date of Patent: June 20, 2017
    Assignees: Kunming Institute of Botany, The Chinese Academy of Sciences, Shanghai Institutes for Biological Sciences, CAS, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences
    Inventors: Xiaojiang Hao, Duozhi Chen, Lin Li, Zonggen Peng, Jiandong Jiang, Yingtong Di, Junlin Yin, Sheng Wang, Jieyun Cai
  • 15-Oxospiramilactone Derivatives, Preparation Method and Uses Thereof
    Publication number: 20160185743
    Abstract: The invention relates to a derivative of 15-oxospiramilacton, particularly to a compound of Formula I or II, or an isomer, a solvate or a pharmaceutically acceptable salt thereof. The invention also relates to a pharmaceutical composition comprising the compound as pharmaceutically active ingredient, a method for preparing the same, and use thereof in manufacture of an anti-tumor agent. The derivative of 15-oxospiramilactone of the invention have an activity against multiple tumor cell lines, and the anti-tumor activity is positively correlated to an activity inhibiting the Wnt signaling pathway.
    Type: Application
    Filed: April 21, 2014
    Publication date: June 30, 2016
    Inventors: Xiaojiang Hao, Chen Yan, Haiyang Liu, Lin Li, Xiaoli He, Quan Chen
  • Phenanthridine Derivatives, Preparation Methods and Uses Thereof
    Publication number: 20160083364
    Abstract: The present invention relates to the pharmaceutical field, in particular to a phenanthridine derivative as shown in general formula (1) a pharmaceutical composition comprising the derivative, its preparation method, and its uses in manufacture of a medicament for the prevention or treatment of a disease related to the activity of Wnt signaling pathway, hepatitis C and hepatitis B.
    Type: Application
    Filed: February 28, 2014
    Publication date: March 24, 2016
    Inventors: Xiaojiang Hao, Duozhi Chen, Lin Li, Zonggen Peng, Jiandong Jiang, Yingtong Di, Junlin Yin, Sheng Wang, Jieyun Cai