Patents by Inventor Xiaojiao YANG

Xiaojiao YANG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compound and use thereof in preparation of BCL-XL inhibitor
    Publication number: 20250333409
    Abstract: Disclosed in the present invention is a compound and the use thereof in preparation of BCL-XL inhibitor, belong to the field of pharmacy. The structure of the compound provided by the present invention is represented in Formula I. The compound can effectively bind to BCL-XL protein, thereby further inhibiting activity of the BCL-XL protein. The compound an be used for preparing a BCL-XL inhibitor and drugs for preventing and/or treating diseases related to the BCL-XL protein activity (such as cancer and autoimmune diseases, etc.), and has broad prospect in clinical application. The compound has good pharmacological characteristics, good stability, high drugability. In assition, the compound has simple preparation method, high yield and low cost, and thus is suitable for industrial production.
    Type: Application
    Filed: May 30, 2023
    Publication date: October 30, 2025
    Applicants: Hitgen Inc., SICHUAN KELUN-BIOTECH BIOPHARMACEUTICAL CO., LTD.
    Inventors: Chuan Liu, Jinming Liu, Dengfeng Dou, Qian Liu, Shuai Xia, Zhengfu Tai, Wei Zhang, Xiaojiao Yang, Longying Cai, Hongmei Song, Jin Li, Junyou Ge
  • DEGRADATION AGENT AND USE THEREOF
    Publication number: 20250136593
    Abstract: A compound having a BCL-XL protein degradation function as shown in Formula I and a use thereof in preparation of a drug for diseases associated with BCL-XL activity.
    Type: Application
    Filed: November 15, 2022
    Publication date: May 1, 2025
    Inventors: Chuan LIU, Jinming LIU, Dengfeng DOU, Zhengfu TAI, Jin LI, Junyou GE, Wei ZHANG, Shuai XIA, Sichuan XIANG, Linfu LUO, Jianbo SHEN, Longying CAI, Qiuxia CHEN, Qian LIU, Hui HUANG, Xiaojiao YANG, Qiang TIAN, Hongmei SONG