Patents by Inventor Xiaojie TU

Xiaojie TU has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • GLYPICAN-2-BINDING MOIETIES, CHIMERIC ANTIGEN RECEPTORS AND USES THEREOF
    Publication number: 20230136252
    Abstract: The present application provides GPC2-specific antibodies and antigen binding fragments thereof. A chimeric antigen receptor (CAR) that specifically binds glypican-2 (GPC2) comprising a GPC2-specific antibody, a transmembrane domain, and an intracellular signaling domain. T cells comprising the disclosed CAR constructs can be used for cancer immunotherapy.
    Type: Application
    Filed: March 12, 2021
    Publication date: May 4, 2023
    Inventors: Wang Zhang, Jintao Guo, Fengyuan TANG, Shuai Yang, Yuanyuan Peng, An Tang, Xiaojie Tu, Yunlei Liu, Shu Wu
  • SINGLE-DOMAIN ANTIBODIES AGAINST CLL1 AND CONSTRUCTS THEREOF
    Publication number: 20210277126
    Abstract: Provided are single-domain antibodies targeting CLL1 and constructs thereof, including chimeric receptors, immune effector cell engagers and immunoconjugates. Further provided are engineered immune effector cells (such as T cells) comprising an anti-CLL1 chimeric receptor and optionally a second chimeric receptor targeting a second antigen or epitope. Pharmaceutical compositions, kits and methods of treating cancer are also provided.
    Type: Application
    Filed: September 10, 2019
    Publication date: September 9, 2021
    Inventors: Wang ZHANG, Yunlei LIU, Xiaojie TU, Chenyu SHU, Tailan ZHAN, Yun ZHANG, An TANG, Yafeng ZHANG, Shu WU, Qing ZHANG