Abstract: Embodiments of the disclosed technologies are capable of providing a ranking of digital content using a machine learning model. The machine learning model is configured for multi-task learning for dependent multi-objective optimization. Embodiments configure a memory according to a machine learning model, where the machine learning model includes a shared backbone and multiple heads. Each of the multiple heads are trained to perform a task associated with a first objective of a second objective.

Abstract: The present disclosure discloses a gradient single-crystal positive electrode material, which has a chemical formula of LiNixCoyA1-x-yO2@mLiaZbOc, wherein 0<x<1, 0<y<1, 0<x+y<1, 0<m<0.05, 0.3<a?10, 1?b<4, and 1?c<15, A is at least one of Mn, Zr, Sr, Ba, W, Ti, Al, Mg, Y, and Nb, and Z is at least one of B, Al, Co, W, Ti, Zr, and Si. The atomic ratio of the content of Co on the surface of the single-crystal positive electrode material particle to the content of Ni+Co+A on the surface is greater than 0.4 and less than 0.8, and the atomic ratio of Co at a depth 10% of the radius from the surface of the single crystal positive electrode material particle is not less than 0.3; and the single-crystal positive electrode material particle has a roundness of greater than 0.4, and is free from sharp corners.

Abstract: A device for extracting polysaccharide from Acaudina molpadioides is provided, which includes a mixing box, a blocking cover, a feed pipe group, a discharge pipe, a bottom plate, a side plate, a first motor, a first transmission shaft, two drive shafts, a first circular gear, two second circular gears, two rotary discs, two connecting frame groups, two semiarc rotary discs, a slide bar, a stop collar, a fixed link, a baffle, a first bushing group and a first sleeve spring group. A top side wall and a rear lower side of the mixing box are communicated with the feed pipe group and the discharge pipe, respectively. Front side and rear sides of the slide bar are longitudinally connected with multiple first engaging teeth. Both the two semiarc rotary discs are connected with multiple second engaging teeth. The fixed link is connected between the stop collar and the slide bar.

Abstract: Disclosed is an imaging device for AMI diagnosis includes a first polarizer is arranged in an imaging part and a second polarizer is arranged in a light source part. These two are linear polarizers, and the polarization directions of the first polarizer and the second polarizer are perpendicular to each other. During the imaging process, a near-infrared beam emitted from a near-infrared light source is modulated into a linearly polarized light with a certain angle when passing through the second polarizer. Then, it is irradiated onto a subject and the light is reflected due to the specular reflection effect of the subject turns into a cross-polarized light when passing through the first polarizer. The linearly polarized light perpendicular to the polarization angle of the first polarizer is intercepted, that is, the reflected light is intercepted.

Abstract: The present application discloses a tooth gel and a tooth strip with remineralization capability, and a preparation method of the tooth gel. The tooth gel includes the following raw material components by mass: 1-35% of active ingredients, 20-60% of thickening agent, 20-70% of solvent, 5-25% of solid dispersant, 0.1-0.8% of essence, 0.1-1.0% of sweetener and 0.1-1.0% of pH regulator; the raw materials for preparing the active ingredients include calcium phosphate and/or bioactive glass; and the tooth strip includes a three-layer structure: an anti-sticking liner, a dental gel layer and a peel-off backing layer, where the anti-sticking liner is adhered to one surface of the dental gel layer, the other surface of the dental gel layer is adhered to the a peel-off backing layer, and the dental gel layer is a tooth gel.

Abstract: Techniques for a flexible data security and machine learning system for merging third-party data are provided. In one technique, the system receives a data set from a third-party entity and receives selection data that indicates that the third-party entity selected a set of data security policies that includes an encryption option and a data mixing option from among multiple data mixing options. In response to receiving the selection data, the system stores data that associates the set of data security policies with the data set, encrypts the data set according to the encryption option, and persistently stores the encrypted data set. Later, the system decrypts the encrypted data set in volatile memory, generates, based on the data mixing option, training data based on the decrypted version of the data set, trains a machine-learned model based on the training data, and stores the machine-learned model in association with the data set.

Abstract: Techniques for a flexible data security and machine learning system for merging third-party data are provided. In one technique, the system receives a data set from a third-party entity and receives selection data that indicates that the third-party entity selected a set of data security policies that includes an encryption option and a data mixing option from among multiple data mixing options. In response to receiving the selection data, the system stores data that associates the set of data security policies with the data set, encrypts the data set according to the encryption option, and persistently stores the encrypted data set. Later, the system decrypts the encrypted data set in volatile memory, generates, based on the data mixing option, training data based on the decrypted version of the data set, trains a machine-learned model based on the training data, and stores the machine-learned model in association with the data set.

Abstract: A roller embossing method for flexible graphite polar plates of fuel cells comprises: (1) adjusting a clearance of an embossing roller pair of a roller press to a target thickness value of a monopolar plate; (2) feeding a flexible graphite slab in front of the embossing roller pair, and entangling the flexible graphite slab by means of opposite rotation of the embossing roller pair; (3) after the slab is entangled, continuing to forward roll the slab for 10-100 mm, and then reversely rolling the slab for 5-90 mm by means of synchronous and opposite rotation of an upper and a lower embossing roller, wherein one time of forward rolling and one time of reverse rolling are referred to as reciprocal rolling; (4) forming a polar plate after several times of reciprocal rolling, and separating the polar plate from the embossing rollers; (5) performing subsequent treatment on the roll-formed flexible graphite polar plate.

Abstract: Implementations generally relate to determining the position of a tool tip of a surgical instrument and the orientation of the surgical instrument. In some implementations, a method includes receiving at least one image frame of a plurality of image frames. The method further includes detecting a surgical tool in the at least one image frame. The method further includes determining a position of a tip of the surgical tool. The method further includes determining an orientation of the surgical tool.

Abstract: A device for extracting polysaccharide from acaudina molpadioides is provided, which includes a mixing box, a blocking cover, a feed pipe group, a discharge pipe, a bottom plate, a side plate, a first motor, a first transmission shaft, two drive shafts, a first circular gear, two second circular gears, two rotary discs, two connecting frame groups, two semiarc rotary discs, a slide bar, a stop collar, a fixed link, a baffle, a first bushing group and a first sleeve spring group. A top side wall and a rear lower side of the mixing box are communicated with the feed pipe group and the discharge pipe, respectively. Front side and rear sides of the slide bar are longitudinally connected with multiple first engaging teeth. Both the two semiarc rotary discs are connected with multiple second engaging teeth. The fixed link is connected between the stop collar and the slide bar.

Abstract: Implementations generally relate to determining tool handedness for surgical videos. In some implementations, a method includes receiving at least one image frame of a plurality of image frames. The method further includes detecting one or more objects in the at least one image frame. The method further includes classifying the one or more objects into one or more tool classifications, where the one or more objects are tools. The method further includes determining, for each tool, if the tool is assistive or non-assistive. The method further includes determining, for each tool, a handedness of the tool.

Abstract: Implementations generally relate to determining the position of a tool tip of a surgical instrument and the orientation of the surgical instrument. In some implementations, a method includes receiving at least one image frame of a plurality of image frames. The method further includes detecting a surgical tool in the at least one image frame. The method further includes determining a position of a tip of the surgical tool. The method further includes determining an orientation of the surgical tool.

Abstract: The present invention relates to the field of immunotherapy, in particular adoptive T cell therapy or T cell receptor (TCR) gene therapy of cancer. The invention provides a nucleic acid encoding at least one T cell receptor alpha chain construct and/or TCR beta chain construct of a TCR construct capable of specifically binding to an epitope from NY-ESO-1 (also designated CTAG-1) in complex with a human MHC, wherein the TCR alpha chain construct and/or the TCR beta chain construct comprises a complementarity determining region 3 (CDR3) having at least 90% sequence identity to an amino acid selected from SEQ ID NO: 1-20. The invention provides TCR constructs restricted to an epitope from NY-ESO-1 presented on MHC I, and, for the first time, TCR constructs restricted to an epitope from NY-ESO-1 presented on MHC II molecules, and thus enables a combined adoptive T cell therapy with both recombinant CD4+ and re-combinant CD8+ T cells.

Abstract: Implementations generally relate to detecting dominant tools in surgical videos. In some implementations, a method includes receiving at least one image frame. The method further includes detecting one or more objects in the at least one image frame. The method further includes classifying the one or more objects into one or more tool classifications, where the one or more objects are tools. The method further includes determining a handedness of the one or more tools. The method further includes determining a dominant tool from the one or more tools based at least in part on the one or more classifications of the one or more tools and based at least in part on the handedness of the one or more tools.

Abstract: A liposome formulation for delivery of Wnt signal pathway inhibitor is provided herein, which comprises lipid molecules and Wnt signal pathway inhibitor, wherein the liposome formulation is prepared through following steps: (1) providing an aqueous solution of the Wnt signal pathway inhibitor and providing an alcoholic solution of the lipid molecules, (2) mixing the aqueous solution of the Wnt signal pathway inhibitor and the alcoholic solution of the lipid molecules, (3) removing alcohol solvent to obtain the liposome formulation with Wnt signal pathway inhibitor encapsulated therein.

Abstract: Implementations generally relate to determining tool handedness for surgical videos. In some implementations, a method includes receiving at least one image frame of a plurality of image frames. The method further includes detecting one or more objects in the at least one image frame. The method further includes classifying the one or more objects into one or more tool classifications, where the one or more objects are tools. The method further includes determining, for each tool, if the tool is assistive or non-assistive. The method further includes determining, for each tool, a handedness of the tool.

Abstract: Implementations generally relate to detecting dominant tools in surgical videos. In some implementations, a method includes receiving at least one image frame. The method further includes detecting one or more objects in the at least one image frame. The method further includes classifying the one or more objects into one or more tool classifications, where the one or more objects are tools. The method further includes determining a handedness of the one or more tools. The method further includes determining a dominant tool from the one or more tools based at least in part on the one or more classifications of the one or more tools and based at least in part on the handedness of the one or more tools.

Abstract: A liposome formulation for delivery of Wnt signal pathway inhibitor is provided herein, which comprises lipid molecules and Wnt signal pathway inhibitor, wherein Wnt signal pathway inhibitor encapsulated within the liposome formulation has a concentration ranging from 0.07 mg/ml to 0.5 mg/ml.

Abstract: A liposome formulation for delivery of Wnt signal pathway inhibitor is provided herein, which comprises lipid molecules and Wnt signal pathway inhibitor, wherein the liposome formulation is prepared through following steps: (1) providing an aqueous solution of the Wnt signal pathway inhibitor and providing an alcoholic solution of the lipid molecules, (2) mixing the aqueous solution of the Wnt signal pathway inhibitor and the alcoholic solution of the lipid molecules, (3) removing alcohol solvent to obtain the liposome formulation with Wnt signal pathway inhibitor encapsulated therein.

Abstract: The present invention relates to the field of immunotherapy, in particular adoptive T cell therapy or T cell receptor (TCR) gene therapy of cancer. The invention provides a nucleic acid encoding at least one T cell receptor alpha chain construct and/or TCR beta chain construct of a TCR construct capable of specifically binding to an epitope from NY-ESO-1 (also designated CTAG-1) in complex with a human MHC, wherein the TCR alpha chain construct and/or the TCR beta chain construct comprises a complementarity determining region 3 (CDR3) having at least 90% sequence identity to an amino acid selected from SEQ ID NO: 1-20. The invention provides TCR constructs restricted to an epitope from NY-ESO-1 presented on MHC I, and, for the first time, TCR constructs restricted to an epitope from NY-ESO-1 presented on MHC II molecules, and thus enables a combined adoptive T cell therapy with both recombinant CD4+ and re-combinant CD8+ T cells.