Patents by Inventor Xiaojuan Lin

Xiaojuan Lin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Furin inhibitors
    Patent number: 11773078
    Abstract: This invention relates to novel compounds according to Formula (I) which are inhibitors of furin, to pharmaceutical compositions containing them, to processes for their preparation, and to their use in therapy for the treatment of fibrotic diseases, including pulmonary fibrosis, renal fibrosis, liver fibrosis, skin fibrosis, ocular fibrosis, cardiac fibrosis, and other miscellaneous fibrotic conditions. The disclosed compounds may also be useful for treating other furin-mediated conditions, including but not limited to, hypertension, cancer, infectious diseases, and genetic disorders (e.g., cystic fibrosis (CF)), and neurodegenerative disorders.
    Type: Grant
    Filed: May 10, 2019
    Date of Patent: October 3, 2023
    Assignee: Glaxosmithkline Intellectual Property Development Limited
    Inventors: Jeffrey Michael Axten, Mui Cheung, Michael P. Demartino, Huiping Amy Guan, Yan Hu, Aaron Bayne Miller, Donghui Qin, Chengde Wu, Zhiliu Zhang, Xiaojuan Lin
  • FURIN INHIBITORS
    Publication number: 20220315556
    Abstract: This invention relates to novel compounds according to Formula (I) which are inhibitors of furin, to pharmaceutical compositions containing them, to processes for their preparation, and to their use in therapy for the treatment of fibrotic diseases, including pulmonary fibrosis, renal fibrosis, liver fibrosis, skin fibrosis, ocular fibrosis, cardiac fibrosis, and other miscellaneous fibrotic conditions. The disclosed compounds may also be useful for treating other furin-mediated conditions, including but not limited to, hypertension, cancer, infectious diseases, and genetic disorders (e.g., cystic fibrosis (CF)), and neurodegenerative disorders.
    Type: Application
    Filed: May 10, 2019
    Publication date: October 6, 2022
    Applicant: Glaxosmithkline Intellectual Property Development Limited
    Inventors: Jeffrey Michael Axten, Mui Cheung, Michael P. Demartino, Huiping Amy Guan, Yan Hu, Aaron Bayne Miller, Donghui Qin, Chengde Wu, Zhiliu Zhang, Xiaojuan Lin
  • BIS-PYRIDYLPYRIDONES AS MELANIN-CONCENTRATING HORMONE RECEPTOR ANTAGONISTS
    Publication number: 20120083489
    Abstract: The invention provides novel bis-pyridylpyridones which are antagonists at the melanin-concentrating hormone receptor 1 (MCHR1), pharmaceutical compositions containing them, processes for their preparation, and their use in therapy and for the treatment of obesity and diabetes.
    Type: Application
    Filed: June 2, 2010
    Publication date: April 5, 2012
    Inventors: Siegfried Benjamin Christensen IV, Donghui Qin, Shenglin Chen, Xing Huang, Di Li, Fei Li, Lei Li, Xiaojuan Lin, Shi Lu, Zhen Lu, Maoyun Lv, Chuanning Wang, Chengde Wu, Mei Xiao, Haiyu Yu, Weina Zhang, Zhiliu Zhang
  • BIS-PYRIDYLPYRIDONES AS MELANIN-CONCENTRATING HORMONE RECEPTOR 1 ANTAGONISTS
    Publication number: 20120077794
    Abstract: The invention provides novel bis-pyridylpyridones which are antagonists at the melanin-concentrating hormone receptor 1 (MCHR1), pharmaceutical compositions containing them, processes for their preparation, and their use in therapy and for the treatment of obesity and diabetes.
    Type: Application
    Filed: June 2, 2010
    Publication date: March 29, 2012
    Applicant: GLAXSMITHKLINE LLC
    Inventors: Siegfried Benjamin Christensen, IV, Donghui Qin, Shenglin Chen, Xing Huang, Di Li, Fei Li, Xiaojuan Lin, Shi Lu, Maoyun Lv, Chengde Wu, Weiliang Xu, Gang Yan, Jianxing Yuan, Weina Zhang, Zhiliu Zhang
  • Harness
    Patent number: D1018997
    Type: Grant
    Filed: September 27, 2021
    Date of Patent: March 19, 2024
    Assignee: HONEYWELL INTERNATIONAL INC.
    Inventors: Zheng Gu, Peng Zhou, Wenbo Wang, Xiaojuan Zhu, Ling Lin, Zhao Xia Jin, Tiecheng Qu, Weiming Zhou, Yolanda Wang, Anncy Zhou
  • Harness relief step
    Patent number: D1018999
    Type: Grant
    Filed: September 27, 2021
    Date of Patent: March 19, 2024
    Assignee: HONEYWELL INTERNATIONAL INC.
    Inventors: Ling Lin, Peng Zhou, Xiaojuan Zhu, Weiming Zhou, Zheng Gu, Lyndon Liu
  • Pivot link
    Patent number: D1022792
    Type: Grant
    Filed: September 27, 2021
    Date of Patent: April 16, 2024
    Assignee: HONEYWELL INTERNATIONAL INC.
    Inventors: Zheng Gu, Peng Zhou, Wenbo Wang, Xiaojuan Zhu, Ling Lin, Lyndon Liu