Patents by Inventor Xiaolan Zhan

Xiaolan Zhan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SALT AND CRYSTAL FORM OF HETEROCYCLIC DERIVATIVE INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF
    Publication number: 20260151378
    Abstract: The present invention relates to a salt and a crystal form of a heterocyclic derivative inhibitor, and a preparation method therefor and the use thereof. Particularly, the present invention relates to a salt and a crystal form of the compound as represented by general formula (I), a preparation method, a pharmaceutical composition containing a therapeutically effective amount of the salt and/or crystal form, and the use thereof as an inhibitor in the treatment of cancers, wherein the definition of each substituent in general formula (I) is as defined in the description.
    Type: Application
    Filed: October 20, 2023
    Publication date: June 4, 2026
    Inventors: Xiaolan ZHAN, Yuanyuan LI, Linsong GUO
  • Three fused ring derivative-containing salt or crystal form and pharmaceutical composition thereof
    Patent number: 12624050
    Abstract: A three fused ring derivative-containing salt and a crystal form thereof. In particular, the present invention relates to a compound having general formula (I), a crystal form thereof, a preparation method therefor, a pharmaceutical composition containing a therapeutically effective amount of the compound and the crystal form thereof, and use thereof in the preparation of a medicament for treating PI3K-mediated related diseases.
    Type: Grant
    Filed: November 19, 2020
    Date of Patent: May 12, 2026
    Assignees: Shanghai Hansoh Biomedical Co., Ltd., Jiangsu Hansoh Pharmaceutical Group Co., Ltd.
    Inventors: Xiaolan Zhan, Linsong Guo
  • CRYSTAL FORM OF FREE ALKALI OF NITROGEN-CONTAINING AROMATIC DERIVATIVES
    Publication number: 20230134869
    Abstract: The present invention relates to a crystal form of the free alkali of nitrogen-containing aromatic derivatives. In particular, the present invention relates to a crystal form of the compound represented by the general formula (I), its preparation method and a pharmaceutical composition containing a therapeutically effective amount of the crystal form, and the use thereof as a protein tyrosine phosphatase-2C (SHP2) inhibitor in the treatment of diseases or conditions such as leukemia, neuroblastoma, melanoma, breast cancer, lung cancer and colorectal cancer.
    Type: Application
    Filed: April 2, 2021
    Publication date: May 4, 2023
    Inventors: Xiaolan Zhan, Linsong Guo
  • THREE FUSED RING DERIVATIVE-CONTAINING SALT OR CRYSTAL FORM AND PHARMACEUTICAL COMPOSITION THEREOF
    Publication number: 20230014383
    Abstract: A three fused ring derivative-containing salt and a crystal form thereof. In particular, the present invention relates to a compound having general formula (I), a crystal form thereof, a preparation method therefor, a pharmaceutical composition containing a therapeutically effective amount of the compound and the crystal form thereof, and use thereof in the preparation of a medicament for treating PI3K-mediated related diseases.
    Type: Application
    Filed: November 19, 2020
    Publication date: January 19, 2023
    Inventors: Xiaolan Zhan, Linsong Guo