Patents by Inventor XiaoLan Zheng

XiaoLan Zheng has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • QUINAZOLINONE DERIVATIVES AND THEIR USE AS B-RAF INHIBITORS
    Publication number: 20090118261
    Abstract: The invention relates to chemical compounds of the formula (I): or pharmaceutically acceptable salts thereof, which possess B Raf inhibitory activity and are accordingly useful for their anti cancer activity and thus in methods of treatment of the human or animal body. The invention also relates to processes for the manufacture of said chemical compounds, to pharmaceutical compositions containing them and to their use in the manufacture of medicaments of use in the production of an anti-cancer effect in a warm blooded animal such as man.
    Type: Application
    Filed: August 26, 2005
    Publication date: May 7, 2009
    Applicant: ASTRAZENECA AB
    Inventors: Brian Aquila, Leslie Dakin, Jayachandran Ezhuthachan, Stephen Lee, Paul Lyne, Timothy Pontz, XiaoLan Zheng
  • ENANTIOMERS OF SELECTED FUSED HETEROCYCLICS AND USES THEREOF
    Publication number: 20090099210
    Abstract: This invention relates to novel compounds having the structural formula (I) and to their pharmaceutical compositions and to their methods of use. These novel compounds provide a treatment or prophylaxis of cancer.
    Type: Application
    Filed: December 22, 2008
    Publication date: April 16, 2009
    Applicant: ASTRAZENECA AB
    Inventors: Brian Aquila, Michael Howard Block, Audrey Davies, Jayachandran Ezhuthachan, Sandra Ann Filla, Timothy Pontz, Daniel John Russell, Maria-Elena Theoclitou, XiaoLan Zheng
  • Enantiomers of selected fused heterocyclics and uses thereof
    Patent number: 7498333
    Abstract: This invention relates to novel compounds having the structural formula (I) and to their pharmaceutical compositions and to their methods of use. These novel compounds provide a treatment or prophylaxis of cancer.
    Type: Grant
    Filed: August 18, 2005
    Date of Patent: March 3, 2009
    Assignee: AstraZeneca AB
    Inventors: Brian Aquila, Michael Howard Block, Audrey Davies, Jayachandran Ezhuthachan, Sandra Ann Filla, Timothy Pontz, Daniel John Russell, Maria-Elena Theoclitou, XiaoLan Zheng
  • 4-ANILINOQUINOLINE-3-CARBOXAMIDES AS CSF-1R KINASE INHIBITORS
    Publication number: 20090054411
    Abstract: The invention relates to chemical compounds of formula IA or IB: or pharmaceutically acceptable salts thereof which possess CSF-1R kinase inhibitory activity and are accordingly useful for their anti-cancer activity and thus in methods of treatment of the human or animal body. The invention also relates to processes for the manufacture of said chemical compounds, to pharmaceutical compositions containing them and to their use in the manufacture of medicaments of use in the production of an anti-cancer effect in a warm-blooded animal such as man.
    Type: Application
    Filed: October 13, 2008
    Publication date: February 26, 2009
    Applicant: AstraZeneca AB
    Inventors: Donald Cook, Leslie Dakin, David Del Valle, Thomas Gero, David Scott, Xiaolan Zheng
  • 3-CINNOLINECARBOXAMIDE DERIVATIVES AND THEIR USE FOR TREATING CANCER
    Publication number: 20090012084
    Abstract: The invention relates to chemical compounds of formula (I): or pharmaceutically acceptable salts thereof which possess CSF-1R kinase inhibitory activity and are accordingly useful for their anti-cancer activity and thus in methods of treatment of the human or animal body. The invention also relates to processes for the manufacture of said chemical compounds, to pharmaceutical compositions containing them and to their use in the manufacture of medicaments of use in the production of an anti-cancer effect in a warm-blooded animal such as man.
    Type: Application
    Filed: September 15, 2008
    Publication date: January 8, 2009
    Applicant: ASTRAZENECA AB
    Inventors: Leslie Dakin, Claude Afona Ogoe, David Scott, XiaoLan Zheng
  • Chemical Compounds-149
    Publication number: 20080312206
    Abstract: The invention relates to chemical compounds, or pharmaceutically acceptable salts thereof of the formula which possess CSF 1R kinase inhibitory activity and are accordingly useful for their anti cancer activity and thus in methods of treatment of the human or animal body. The invention also relates to processes for the manufacture of said chemical compounds, to pharmaceutical compositions containing them and to their use in the manufacture of medicaments of use in the production of an anti-cancer effect in a warm blooded animal such as man.
    Type: Application
    Filed: December 19, 2006
    Publication date: December 18, 2008
    Applicant: AstraZeneca AB
    Inventors: Brian Aquila, Donald Cook, Leslie Dakin, Stephanos Ioannidis, Paul Lyne, David Scott, Xiaolan Zheng
  • Quinazoline Derivatives, Process for Their Preparation and Their Use as Anti-Cancer Agents
    Publication number: 20080306096
    Abstract: The invention relates to chemical compounds of the formula (I) or pharmaceutically acceptable salts thereof, which possess B Raf inhibitory activity and are accordingly useful for their anti cancer activity and thus in methods of treatment of the human or animal body. The invention also relates to processes for the manufacture of said chemical compounds, to pharmaceutical compositions containing them and to their use in the manufacture of medicaments of use in the production of an anti-cancer effect in a warm blooded animal such as man.
    Type: Application
    Filed: December 19, 2006
    Publication date: December 11, 2008
    Applicant: ASTRAZENECA AB
    Inventors: Brian Aquila, Jayachandran Ezhuthachan, Paul Lyne, Timothy Pontz, Xiaolan Zheng
  • Enantiomers of Selected Fused Pyrimidones and Uses in the Treatment and Prevention of Cancer
    Publication number: 20080293744
    Abstract: This invention relates to novel compounds having the structural formula (I) and to their pharmaceutical compositions and to their methods of use. These novel compounds provide a treatment or prophylaxis of cancer.
    Type: Application
    Filed: August 16, 2005
    Publication date: November 27, 2008
    Applicant: ASTRAZENECA AB
    Inventors: Brian Aquila, Michael Howard Block, Audrey Davies, Jayachandran Ezhuthachan, Timothy Pontz, Daniel John Russell, Marie-Elena Theoclitou, XiaoLan Zheng
  • NOVEL FUSED HETEROCYCLES AND USES THEREOF
    Publication number: 20080153854
    Abstract: This invention relates to novel compounds having the formula (I) wherein R1, R2, R3, R4, R5, R6, R7, R8 and R9 are as defined in the specification and to their pharmaceutical compositions and to their methods of use. These novel compounds provide a treatment or prophylaxis of cancer.
    Type: Application
    Filed: February 15, 2008
    Publication date: June 26, 2008
    Applicant: AstraZeneca AB
    Inventors: Brian Aquila, Michael Howard Block, Audrey Davies, Jayachandran Ezhuthachan, Sandra Filla, Richard William Luke, Timothy Pontz, Daniel John Russell, Maria-Elena Theoclitou, XiaoLan Zheng
  • Selected Fused Heterocyclics and Uses Thereof
    Publication number: 20070249636
    Abstract: This invention relates to novel compounds having the structural formula (I) and to their pharmaceutical compositions and to their methods of use. These novel compounds provide a treatment or prophylaxis of cancer.
    Type: Application
    Filed: August 16, 2005
    Publication date: October 25, 2007
    Applicant: ASTRAZENECA AB
    Inventors: Brian Aquila, Michael Block, Audrey Davies, Jayachandran Ezhuthachan, Timothy Pontz, Daniel Russell, Marie-Elena Theoclitou, XiaoLan Zheng
  • Novel fused heterocycles and uses thereof
    Publication number: 20060063751
    Abstract: This invention relates to novel compounds having the formula (I) wherein R1, R2, R3, R4, R5, R6, R7, R8 and R9 are as defined in the specification and to their pharmaceutical compositions and to their methods of use. These novel compounds provide a treatment or prophylaxis of cancer.
    Type: Application
    Filed: August 18, 2005
    Publication date: March 23, 2006
    Applicant: AstraZeneca AB
    Inventors: Brian Aquila, Michael Block, Audrey Davies, Jayachandran Ezhuthachan, Sandra Filla, Richard Luke, Timothy Pontz, Daniel Russell, Maria-Elena Theoclitou, XiaoLan Zheng
  • Selected fused heterocyclics and uses thereof
    Publication number: 20060041128
    Abstract: This invention relates to novel compounds having the structural formula (I) and to their pharmaceutical compositions and to their methods of use. These novel compounds provide a treatment or prophylaxis of cancer.
    Type: Application
    Filed: August 18, 2005
    Publication date: February 23, 2006
    Applicant: AstraZeneca AB
    Inventors: Brian Aquila, Michael Block, Audrey Davies, Jayachandran Ezhuthachan, Timothy Pontz, Daniel Russell, Maria-Elena Theoclitou, XiaoLan Zheng
  • Enantiomers of selected fused heterocyclics and uses thereof
    Publication number: 20060041129
    Abstract: This invention relates to novel compounds having the structural formula (I) and to their pharmaceutical compositions and to their methods of use. These novel compounds provide a treatment or prophylaxis of cancer.
    Type: Application
    Filed: August 18, 2005
    Publication date: February 23, 2006
    Applicant: AstraZeneca AB
    Inventors: Brian Aquila, Michael Howard Block, Audrey Davies, Jayachandran Ezhuthachan, Timothy Pontz, Daniel John Russell, Maria-Elena Theoclitou, XiaoLan Zheng