Patents by Inventor Xiaolei Liu

Xiaolei Liu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210155714
    Abstract: A hybridoma cell stain and a monoclonal antibody secreted therefrom and application thereof belong to the technical field of prevention and treatment of Trichinella spiralis (T. spiralis). Aiming at the technical problem of how to specifically diagnose trichinellosis, the disclosure provides a hybridoma cell strain deposited under an accession number of CGMCC No. 18317. Tests show that the monoclonal antibody Ts-ZH68-2A4-Ab secreted by the hybridoma cell strain can compete with the positive serum of pigs infected with T. spiralis for binding to Ts-ZH68 antigen, and the recognition peptide is 222GVDRSATCQGDSGGP236. The monoclonal antibody of the disclosure and the Ts-ZH68 protein B cell epitope polypeptide recognized by the monoclonal antibody can be used to prepare a reagent or a vaccine for diagnosing or preventing infection of T. spiralis, laying the foundation for establishment of a serological diagnosis method of T. spiralis.
    Type: Application
    Filed: December 4, 2020
    Publication date: May 27, 2021
    Inventors: Mingyuan LIU, Xiaolei LIU, Yong YANG, Xuelin WANG, Xue BAI, Bin TANG, Jing DING
  • Patent number: 11008859
    Abstract: The present invention discloses a method for analyzing coalbed methane geological selection of a multi-coalbed high ground stress region, including the following steps: defining the concepts of a favorable area, a sweet spot area, and a sweet spot section; carrying out the selection process on the favorable area, the sweet spot area and the sweet spot section in sequence; selecting different indicators for the characteristics of each stage, explicitly presenting key indicators and reference indicators at each stage, and providing an indicator with one-vote veto rights in the key indicators; and carrying out comprehensive analysis to obtain favorable planar areas and vertical intervals of coalbed methane exploration and development in the multi-coalbed high ground stress region. The method of the present invention provides instructions on coalbed methane geological selection of a multi-coalbed high ground stress region, and is of great significance for the development of coalbed methane.
    Type: Grant
    Filed: May 25, 2018
    Date of Patent: May 18, 2021
    Assignee: China University of Mining and Technology
    Inventors: Caifang Wu, Xiaolei Liu, Shunxi Liu, Mingyang Du, Shasha Zhang, Erchao Zhang
  • Patent number: 11005392
    Abstract: An apparatus is provided. The apparatus includes a bidirectional comb drive actuator. The apparatus may also include a cantilever. The cantilever includes a first end connected to the bidirectional comb drive actuator and a second end connected to an inner frame. In addition, the cantilever may include first and second conductive layers for routing electrical signals. Embodiments of the disclosed apparatuses, which may include multi-dimensional actuators, allow for an increased number of electrical signals to be routed to the actuators. Moreover, the disclosed apparatuses allow for actuation multiple directions, which may provide for increased control, precision, and flexibility of movement. Accordingly, the disclosed embodiments provide significant benefits with regard to optical image stabilization and auto-focus capabilities, for example in size- and power-constrained environments.
    Type: Grant
    Filed: January 18, 2019
    Date of Patent: May 11, 2021
    Assignee: MEMS DRIVE (NANJING) CO., LTD
    Inventors: Xiaolei Liu, Roman Gutierrez, Matthew Ng, Guiqin Wang
  • Publication number: 20210107077
    Abstract: A portable wire cutting device for sampling a steel ingot includes a wire rack device, a driving system, and a multi-axis moving device. The wire rack device includes a first corner wheel, a second corner wheel, a transition wheel, a steering wheel, a first wire rack, a second wire rack, and a wire winding drum. The driving system includes a wire drum motor and a molybdenum wire, wherein the wire drum motor provides power driving for the operation of a cutting line; and the molybdenum wire is a closed molybdenum wire coil connected in an end-to-end manner, the molybdenum wire is wrapped around the first corner wheel, the second corner wheel, the wire winding drum, and an inner side of the transition wheel in a looping manner, and during operation, the cutting line performs wire cutting on an object by the molybdenum wire.
    Type: Application
    Filed: October 9, 2018
    Publication date: April 15, 2021
    Applicant: NANJING DEVELOP ADVANCED MANUFACTURING CO., LTD.
    Inventors: Lingjun HE, Changhua CHEN, Hong ZHANG, Li ZHANG, Leijun SONG, Jiayin XU, Chaogang SHI, Yangdao GONG, Yao HA, Xiaolei LIU, Jiao WANG, Xinhua CHEN
  • Publication number: 20210088804
    Abstract: A multi-axis MEMS assembly is configured to provide multi-axis movement and includes: a first in-plane MEMS actuator configured to enable movement along at least an X-axis; and a second in-plane MEMS actuator configured to enable movement along at least a Y-axis; wherein the first in-plane MEMS actuator is coupled to the second in-plane MEMS actuator.
    Type: Application
    Filed: September 18, 2020
    Publication date: March 25, 2021
    Inventors: MATTHEW NG, Xiaolei Liu, Guiqin Wang
  • Patent number: 10910959
    Abstract: An apparatus is provided. The apparatus includes a bidirectional comb drive actuator. The apparatus may also include a cantilever. The cantilever includes a first end connected to the bidirectional comb drive actuator and a second end connected to an inner frame. In addition, the cantilever may include first and second conductive layers for routing electrical signals. Embodiments of the disclosed apparatuses, which may include multi-dimensional actuators, allow for an increased number of electrical signals to be routed to the actuators. Moreover, the disclosed apparatuses allow for actuation multiple directions, which may provide for increased control, precision, and flexibility of movement. Accordingly, the disclosed embodiments provide significant benefits with regard to optical image stabilization and auto-focus capabilities, for example in size- and power-constrained environments.
    Type: Grant
    Filed: January 18, 2019
    Date of Patent: February 2, 2021
    Assignee: MEMS Drive, Inc.
    Inventors: Xiaolei Liu, Roman Gutierrez, Matthew Ng, Guiqin Wang
  • Publication number: 20210003537
    Abstract: A dudou-shaped test block includes a testing structure, a first beam-path structure, and a second beam-path structure. A first arc-shaped groove and a second arc-shaped groove are provided on one side of the testing structure. The other side of the testing structure is a flat surface. The first beam-path structure and the second beam-path structure are both flat plates. A thickness of the first beam-path structure is less than a thickness of the second beam-path structure. The first beam-path structure and the second beam-path structure are both in contact with the flat surface and arranged parallel to the flat surface. The first arc-shaped groove is arranged corresponding to the first beam-path structure, and the second arc-shaped groove is arranged corresponding to the second beam-path structure.
    Type: Application
    Filed: October 9, 2018
    Publication date: January 7, 2021
    Applicant: NANJING DEVELOP ADVANCED MANUFACTURING CO., LTD.
    Inventors: Changhua CHEN, Li ZHANG, Hong ZHANG, Zhengmao XU, Zheng DONG, Qingyong CHEN, Xiaolei LIU, Yao HA
  • Patent number: 10875761
    Abstract: A micro-electrical-mechanical system (MEMS) device includes one or more slidable connection assemblies for releasably coupling the micro-electrical-mechanical system (MEMS) device to a wafer from which the micro-electrical-mechanical system (MEMS) device was made. The MEMS device may include a MEMS actuation core, and a MEMS electrical connector assembly electrically coupled to the MEMS actuation core configured to be electrically coupled to a printed circuit board.
    Type: Grant
    Filed: September 8, 2017
    Date of Patent: December 29, 2020
    Assignee: MEMS Drive, Inc.
    Inventors: Matthew Ng, Xiaolei Liu, Guiqin Wang
  • Publication number: 20200355590
    Abstract: The present invention discloses a system for measuring the mechanical properties of sea floor sediments at full ocean depth.
    Type: Application
    Filed: April 1, 2019
    Publication date: November 12, 2020
    Applicant: OCEAN UNIVERSITY OF CHINA
    Inventors: Yonggang JIA, Hong ZHANG, Xiaolei LIU, Hongxian SHAN
  • Patent number: 10834504
    Abstract: A temperature detecting and controlling integration device for the micro speaker is provided. After the filter receives an input signal, the power amplifier adjusts the power amplification, and the multi-frequency detection signal is generated with the waveform generator. The extracted signal is generated to drive the micro speaker to emit a sound signal. Afterwards, the voltage signals are extracted at two ends of the coil and the temperature signal is obtained by converting, capturing, and integrating to pass the temperature value to the external device, and the temperature value of the non-linear temperature-controlling unit is analyzed to adjust the compensation gain in real time. The smoothly control of speaker temperature and stable playback of the sound signals is played that can be achieved.
    Type: Grant
    Filed: November 13, 2019
    Date of Patent: November 10, 2020
    Assignee: XIAMEN FOURIER ELECTRONICS CO., LTD.
    Inventors: Xuexin Ding, Weiji Liu, Jian Xu, Lin Zhang, Xiaolei Liu, Yingshun Jiang, Fangkang Shen
  • Patent number: 10815119
    Abstract: Shock-resistant MEMS structures are disclosed. In one implementation, a motion control flexure for a MEMS device includes: a rod including a first and second end, wherein the rod is tapered along its length such that it is widest at its center and thinnest at its ends; a first hinge directly coupled to the first end of the rod; and a second hinge directly coupled to the second of the rod. In another implementation, a conductive cantilever for a MEMS device includes: a curved center portion includes a first and second end, wherein the center portion has a point of inflection; a first root coupled to the first end of the center portion; and a second root coupled to the second end of the center portion. In yet another implementation, a shock stop for a MEMS device is described.
    Type: Grant
    Filed: January 18, 2019
    Date of Patent: October 27, 2020
    Assignee: MEMS Drive, Inc.
    Inventors: Gerardo Morabito, Xiaolei Liu, Guiqin Wang, Roman Gutierrez, Matthew Ng
  • Patent number: 10807857
    Abstract: A micro-electrical-mechanical system (MEMS) cantilever assembly includes an intermediary cantilever portion, a main cantilever arm configured to couple a moveable portion of a micro-electrical-mechanical system (MEMS) and the intermediary cantilever portion, and a plurality of intermediary links configured to couple the intermediary cantilever portion to a portion of the micro-electrical-mechanical system (MEMS).
    Type: Grant
    Filed: September 8, 2017
    Date of Patent: October 20, 2020
    Assignee: MEMS Drive, Inc.
    Inventors: Xiaolei Liu, Matthew Ng, Guiqin Wang, Gerardo Morabito
  • Publication number: 20200325597
    Abstract: Provided is a pig genome-wide specific sgRNA library, a preparation method therefor, and an application thereof. The sgRNA is targeted at a pig genome-wide protein-coding gene, lincRNA and/or miRNA. Specifically, an sgRNA construct has the following structure: AL-N20-AR, wherein AL is the left homology arm sequence located at the upstream of the coding sequence of a pig specific SgRNA, N20 is the coding sequence of the pig specific SgRNA, and AR is a right homology arm sequence located at the downstream of the coding sequence of the pig specific sgRNA. The sgRNA library can be used for screening functional genes of a pig or for preparing a kit.
    Type: Application
    Filed: August 21, 2017
    Publication date: October 15, 2020
    Inventors: Shuhong ZHAO, Shengsong XIE, Changzhi ZHAO, Xinyun LI, Xiangdong LIU, Xiaosong HAN, Gaojuan YANG, Yang GAO, Yilong CHEN, Xiaoyong DU, Yiliang MIAO, Yunlong MA, Xiaolei LIU
  • Publication number: 20200284709
    Abstract: The present invention discloses a second-generation in-situ test device for strength of a shallow water sediment, including a workboat and a static cone penetration test unit carried by the workboat, where the static cone penetration unit includes a mounting frame, a penetration unit, a control cabin and a hydraulic unit; the penetration unit and the hydraulic unit are both electrically connected to the control cabin. In this solution, the workboat is used to carry the test equipment, and the static cone penetration test unit is carried on the workboat with a special structure. Based on a double-cable lifting frame, the equipment is launched and recovered through a moon pool in the center of a hull. This significantly improves the efficiency and safety of the sediment strength test operation in a shallow water environment.
    Type: Application
    Filed: January 30, 2020
    Publication date: September 10, 2020
    Inventors: Xiaolei Liu, Hong Zhang, Yonggang Jia, Jiewen Zheng, Hongxian Shan
  • Publication number: 20200240927
    Abstract: A method for detecting dirt on a screen, a device for the same, an electronic device and a computer-readable storage medium are provided. The method includes acquiring a first image of the screen when the screen is displaying a first picture, determining a dirt detection area in the first image with a mask image, and detecting a position of the dirt within the dirt detection area. With the method provided by the embodiments of the disclosure, the positon of dirt on the screen could be detected based on at most two images of the screen. The time for detecting dirt on the screen is greatly shortened, and the efficiency of detection is enhanced.
    Type: Application
    Filed: August 30, 2019
    Publication date: July 30, 2020
    Inventors: Xiaolei LIU, Yunqi WANG, Minglei CHU, Lili CHEN, Hao ZHANG
  • Publication number: 20200234420
    Abstract: A method for detecting image defects is described, which includes obtaining an image to be detected, down-sampling the image to be detected to obtain a down-sampled image, de-cluttering the down-sampled image to obtain a de-cluttered image, restoring the de-cluttered image into a restored image having the same resolution as the image to be detected so as to be used as a background image, and comparing the image to be detected with the background image to determine defects in the image to be detected. An apparatus for detecting image defects, a computing device and a storage medium are also described.
    Type: Application
    Filed: August 30, 2019
    Publication date: July 23, 2020
    Inventors: Xiaolei LIU, Lili CHEN, Yunqi WANG, Minglei CHU
  • Publication number: 20200152856
    Abstract: A method of generating a piezoelectric actuator includes: forming a piezoelectric member upon a rigid substrate; and removing one or more portions of the rigid substrate to form one or more gaps in the rigid substrate, thus defining at least one deformable portion of the piezoelectric member and at least one rigid portion of the piezoelectric member
    Type: Application
    Filed: November 10, 2019
    Publication date: May 14, 2020
    Inventors: Guiqin Wang, Xiaolei Liu, Mahmood Samiee, Yufeng Wang
  • Publication number: 20200144935
    Abstract: A comb drive includes an inactive comb finger array and an opposing active comb finger array positioned to oppose the inactive comb finger array and configured to move in a non-linear path relative to the inactive comb finger array, wherein each comb finger array includes a comb spine and a plurality of comb fingers extending from its comb spine, and each comb finger on the active comb finger array is shaped to match a non-parallel profile. The non-parallel profile may be tapered, curved, or selected to linearize the capacitance in a gap between adjacent comb fingers from the inactive comb finger array when a comb finger from the active comb finger array moves through the gap.
    Type: Application
    Filed: December 12, 2019
    Publication date: May 7, 2020
    Inventors: Xiaolei Liu, Guiqin Wang, Roman Gutierrez
  • Publication number: 20200144936
    Abstract: A package for moving a platform in six degrees of freedom, is provided. The platform may include an optoelectronic device mounted thereon. The package includes an in-plane actuator which may be a MEMS actuator and an out-of-plane actuator which may be formed of a piezoelectric element. The in-plane MEMS actuator may be mounted on the out-of-plane actuator mounted on a recess in a PCB. The in-plane MEMS actuator includes a plurality comb structures in which fingers of opposed combs overlap one another, i.e. extend past each other's ends. The out-of-plane actuator includes a central portion and a plurality of surrounding stages that are connected to the central portion. The in-plane MEMS actuator is coupled to the out-of-plane Z actuator to provide three degrees of freedom to the payload which may be an optoelectronic device included in the package.
    Type: Application
    Filed: December 23, 2019
    Publication date: May 7, 2020
    Inventors: Xiaolei Liu, Guiqin Wang, Matthew Ng
  • Patent number: 10640176
    Abstract: An observation system and determination method for the re-suspension quantity of submarine sediments by deep-sea internal waves. The observation system comprises a submarine observation platform, a mooring rope, and an anchor mooring counterweight. Acoustic release transponder, a single-point current meter, a turbidity meter, a high-precision temperature and salinity detector, and a sediment catcher are mounted on the submarine observation platform. A main floating body and auxiliary floating bodies are arranged on the mooring rope, wherein the main floating body is located in the middle of the mooring rope and is equipped with acoustic Doppler current profilers, and the auxiliary floating bodies are equipped with turbidity meters and high-precision temperature and salinity detectors. The anchor mooring counterweight is a gravity anchor provided with a square clamping groove and a fixed ring.
    Type: Grant
    Filed: December 20, 2018
    Date of Patent: May 5, 2020
    Assignee: OCEAN UNIVERSITY OF CHINA
    Inventors: Yonggang Jia, Zhuangcai Tian, Shaotong Zhang, Bowen Zhang, Zhiming Wei, Xiaolei Liu, Hongxian Shan