Patents by Inventor Xiaolei Zhuang

Xiaolei Zhuang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • HUMAN NEUREGULIN-1 (NRG-1) RECOMBINANT FUSION PROTEIN COMPOSITIONS AND METHODS OF USE THEREOF
    Publication number: 20230322877
    Abstract: The present invention relates to a recombinant fusion protein comprising a fragment of the cardioprotective protein neuregulin-1 (NRG-1) fused to a monoclonal antibody (mAb) backbone and to a method of treating a disease or condition in a subject in need thereof comprising administering a therapeutically effective amount of the recombinant fusion protein or the pharmaceutical composition comprising the recombinant fusion protein disclosed herein.
    Type: Application
    Filed: June 13, 2023
    Publication date: October 12, 2023
    Inventors: John Li, Shengwei Li, Dixiang Luo, Yiran Wu, Ming Zhou, Yang Wang, Xiaolei Zhuang, Liang Hua, Pengyi Luo
  • Human neuregulin-1 (NRG-1) recombinant fusion protein compositions and methods of use thereof
    Patent number: 11718652
    Abstract: The present invention relates to a recombinant fusion protein comprising a fragment of the cardioprotective protein neuregulin-1 (NRG-1) fused to a monoclonal antibody (mAb) backbone and to a method of treating a disease or condition in a subject in need thereof comprising administering a therapeutically effective amount of the recombinant fusion protein or the pharmaceutical composition comprising the recombinant fusion protein disclosed herein.
    Type: Grant
    Filed: May 21, 2021
    Date of Patent: August 8, 2023
    Assignees: Salubris Biotherapeutics, Inc.
    Inventors: John Li, Shengwei Li, Dixiang Luo, Yiran Wu, Ming Zhou, Yang Wang, Xiaolei Zhuang, Liang Hua, Pengyi Luo
  • HUMAN NEUREGULIN-1 (NRG-1) RECOMBINANT FUSION PROTEIN COMPOSITIONS AND METHODS OF USE THEREOF
    Publication number: 20210347841
    Abstract: The present invention relates to a recombinant fusion protein comprising a fragment of the cardioprotective protein neuregulin-1 (NRG-1) fused to a monoclonal antibody (mAb) backbone and to a method of treating a disease or condition in a subject in need thereof comprising administering a therapeutically effective amount of the recombinant fusion protein or the pharmaceutical composition comprising the recombinant fusion protein disclosed herein.
    Type: Application
    Filed: May 21, 2021
    Publication date: November 11, 2021
    Inventors: John LI, Shengwei LI, Dixiang LUO, Yiran WU, Ming ZHOU, Yang WANG, Xiaolei ZHUANG, Liang HUA, Pengyi LUO
  • Human neuregulin-1 (NRG-1) recombinant fusion protein compositions and methods of use thereof
    Patent number: 11046741
    Abstract: The present invention relates to a recombinant fusion protein comprising a fragment of the cardioprotective protein neuregulin-1 (NRG-1) fused to a monoclonal antibody (mAb) backbone and to a method of treating a disease or condition in a subject in need thereof comprising administering a therapeutically effective amount of the recombinant fusion protein or the pharmaceutical composition comprising the recombinant fusion protein disclosed herein.
    Type: Grant
    Filed: April 11, 2019
    Date of Patent: June 29, 2021
    Assignees: Salubris Biotherapeutics, Inc., Salubris (Chengdu) Biotech Co., Ltd.
    Inventors: John Li, Shengwei Li, Dixiang Luo, Yiran Wu, Ming Zhou, Xiaolei Zhuang, Liang Hua, Pengyi Luo, Yang Wang
  • HUMAN NEUREGULIN-1 (NRG-1) RECOMBINANT FUSION PROTEIN COMPOSITIONS AND METHODS OF USE THEREOF
    Publication number: 20200010522
    Abstract: The present invention relates to a recombinant fusion protein comprising a fragment of the cardioprotective protein neuregulin-1 (NRG-1) fused to a monoclonal antibody (mAb) backbone and to a method of treating a disease or condition in a subject in need thereof comprising administering a therapeutically effective amount of the recombinant fusion protein or the pharmaceutical composition comprising the recombinant fusion protein disclosed herein.
    Type: Application
    Filed: April 11, 2019
    Publication date: January 9, 2020
    Inventors: John LI, Shengwei LI, Dixiang LUO, Yiran WU, Ming ZHOU, Xiaolei Zhuang, Liang HUA, Pengyi LUO, Yang WANG
  • MICRO-OPTICAL DEVICE DOUBLE-SIDED IMAGING, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF
    Publication number: 20180111405
    Abstract: A micro-optical device for double-sided imaging, a preparation method therefor and an application thereof. The micro-optical device for double-sided imaging comprises a first microlens layer (1), a functional layer (4), a second microlens layer (2) and a miniature graphic layer (3) which are mutually compounded in sequence, the first microlens layer (1) being a first microlens array formed by arranging a plurality of first microlenses (11), and the second microlens layer (2) being a second microlens array formed by arranging a plurality of second microlenses (21); and the functional layer (4) is arranged on the surface of the second microlens layer (2), and a material for the functional layer (4) has a refractive index different from that of a surrounding material.
    Type: Application
    Filed: December 9, 2015
    Publication date: April 26, 2018
    Inventors: Liangheng Xu, Xiaolei Zhuang, Lanxin Dong, Renshun You