Patents by Inventor Xiaoli Cui

Xiaoli Cui has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • C-SHAPED OR U-SHAPED HALF-COIL, ROTOR WINDING WITH SUCH A HALF-COIL AND ITS MANUFACTUING METHOD
    Publication number: 20170033629
    Abstract: Embodiments of the present invention relate to a winding of a rotor for use in rotating electrical machines. More particularly, embodiments of the present invention relate to innovative half-coils used for the winding of the rotor. Moreover, embodiments of the invention pertain to a method for winding a rotor body of an electrical machine. According to embodiments of the invention, half-coils, instead of being manufactured as double hollow conductors, are provided in the form of two single hollow conductors, which are adjacently embedded within a respective slot of the rotor body.
    Type: Application
    Filed: April 1, 2015
    Publication date: February 2, 2017
    Inventors: Johann HALDEMANN, Xiaoli CUI, Christian AUGE, Carsten MEINECKE, Matthias MUNDSTOCK, Walter SOEHNER
  • Methods and compositions for the diagnosis and treatment of cancer resistant to anaplastic lymphoma kinase (ALK) kinase inhibitors
    Patent number: 9458508
    Abstract: Compositions and methods for the diagnosis and treatment of a cancer that is resistant to at least one anaplastic lymphoma kinase (ALK) kinase inhibitor are provided herein. The present invention is based on the discovery of mutations within ALK that confer resistance to at least one ALK kinase inhibitor. Polynucleotides and polypeptides having at least one ALK inhibitor resistance mutation are provided and find use in methods and compositions useful in the diagnosis, prognosis, and/or treatment of diseases associated with aberrant ALK activity, more particularly, those that are resistant to at least one ALK kinase inhibitors. Methods and compositions are also provided for the identification of agents that can inhibit the kinase activity and/or reduce the expression level of the ALK resistance mutants.
    Type: Grant
    Filed: February 20, 2013
    Date of Patent: October 4, 2016
    Assignee: St. Jude Children's Research Hospital
    Inventors: Stephan W. Morris, Qin Jiang, Xiaoli Cui, Liquan Xue
  • Methods And Compositions For The Diagnosis And Treatment Of Cancer Resistant To Anaplastic Lymphoma Kinase (ALK) Kinase Inhibitors
    Publication number: 20130244893
    Abstract: Compositions and methods for the diagnosis and treatment of a cancer that is resistant to at least one anaplastic lymphoma kinase (ALK) kinase inhibitor are provided herein. The present invention is based on the discovery of mutations within ALK that confer resistance to at least one ALK kinase inhibitor. Polynucleotides and polypeptides having at least one ALK inhibitor resistance mutation are provided and find use in methods and compositions useful in the diagnosis, prognosis, and/or treatment of diseases associated with aberrant ALK activity, more particularly, those that are resistant to at least one ALK kinase inhibitors. Methods and compositions are also provided for the identification of agents that can inhibit the kinase activity and/or reduce the expression level of the ALK resistance mutants.
    Type: Application
    Filed: February 20, 2013
    Publication date: September 19, 2013
    Applicant: St. Jude Children's Research Hospital
    Inventors: Stephen W. Morris, Qin Jiang, Xiaoli Cui, Liquan Xue
  • Methods and compositions for the diagnosis and treatment of cancer resistant to anaplastic lymphoma kinase (ALK) kinase inhibitors
    Patent number: 8383793
    Abstract: Compositions and methods for the diagnosis and treatment of a cancer that is resistant to at least one anaplastic lymphoma kinase (ALK) kinase inhibitor are provided herein. The present invention is based on the discovery of mutations within ALK that confer resistance to at least one ALK kinase inhibitor. Polynucleotides and polypeptides having at least one ALK inhibitor resistance mutation are provided and find use in methods and compositions useful in the diagnosis, prognosis, and/or treatment of diseases associated with aberrant ALK activity, more particularly, those that are resistant to at least one ALK kinase inhibitors. Methods and compositions are also provided for the identification of agents that can inhibit the kinase activity and/or reduce the expression level of the ALK resistance mutants.
    Type: Grant
    Filed: April 15, 2010
    Date of Patent: February 26, 2013
    Assignee: St. Jude Children's Research Hospital
    Inventors: Stephan W. Morris, Qin Jiang, Xiaoli Cui, Liquan Xue
  • METHODS AND COMPOSITIONS FOR THE DIAGNOSIS AND TREATMENT OF CANCER RESISTANT TO ANAPLASTIC LYMPHOMA KINASE (ALK) KINASE INHIBITORS
    Publication number: 20110256546
    Abstract: Compositions and methods for the diagnosis and treatment of a cancer that is resistant to at least one anaplastic lymphoma kinase (ALK) kinase inhibitor are provided herein. The present invention is based on the discovery of mutations within ALK that confer resistance to at least one ALK kinase inhibitor. Polynucleotides and polypeptides having at least one ALK inhibitor resistance mutation are provided and find use in methods and compositions useful in the diagnosis, prognosis, and/or treatment of diseases associated with aberrant ALK activity, more particularly, those that are resistant to at least one ALK kinase inhibitors. Methods and compositions are also provided for the identification of agents that can inhibit the kinase activity and/or reduce the expression level of the ALK resistance mutants.
    Type: Application
    Filed: April 15, 2010
    Publication date: October 20, 2011
    Applicant: ST. JUDE CHILDREN'S RESEARCH HOSPITAL
    Inventors: STEPHAN W. MORRIS, QIN JIANG, Xiaoli Cui, Liquan Xue