Abstract: The disclosure provides for methods, compositions and kits that utilize total Oxidized phospholipids to determine whether a subject has liver disease.

Abstract: A retinoic acid modified lysosome targeting chimera (LYTAC) molecule, a preparation method and applications thereof are provided. A structural formula of the retinoic acid modified LYTAC molecule is in which, n represents a molecular weight of polyethylene glycol (PEG), n is in a range of 60 to 5000, R is one of an antibody, a polypeptide and a micromolecule compound targeting a targeted protein. The retinoic acid modified LYTAC molecule can be applied to targeted protein degradation and preparation of tumor cell activity inhibitors. Retinoic acid has high biosafety, is easy to obtain and modify, and has a broad application prospect.

Abstract: Disclosed herein is a bolt axial force measurement method, device, apparatus, and readable storage medium, the method comprises steps of: capturing an image of a bridge bolt; identifying an outer edge of a nut, a centroid of the nut, and a circular position of a laser spot in a captured image of the bridge bolt; projecting a calibration laser spot onto a bolt plate and obtaining a current frame as a bolt-detection image; performing dimensional calibration on the bolt-detection image and determining a displacement of each of the pre-calibrated feature points; calculating a bolt axial force value based on the displacement. The solution captures images of the bridge bolts and analyzes positions of each of the pre-calibrated feature points in the images; thus, the bolt axial force can be measured non-destructively, and non-rotational loosening of bolts can be identified.

Abstract: A preparation and use of a green alternative template molecularly imprinted-carbon quantum dot nanogel fluorescent sensor. The morphology, chemical structure, and optical properties of the fluorescent sensor were investigated using techniques such as Transmission Electron Microscopy (TEM), X-ray Photoelectron Spectroscopy (XPS), Fourier Transform Infrared Spectroscopy (FTIR), Fluorescence Spectroscopy. Using Bisphenol A as a detection model, the selectivity and sensitivity of the sensor were evaluated based on changes in fluorescence intensity. The green alternative template molecularly imprinted-carbon quantum dot nanogel sensor provided by the present disclosure exhibits excellent selectivity, high sensitivity, and a low detection limit. It can achieve highly selective recognition of Bisphenol A in plastic barrel-packed Baijiu samples and is suitable for the enrichment and purification of Bisphenol A in organic phases.

Abstract: In the automatic welding method and device for prestressed tubular piles provided in the present application, which is applied in welding equipment, a detection is conducted around a connection position between prestressed tubular piles and a position of a target welding seam is obtained. Then the target welding seam is welded around the prestressed tubular piles according to the position of the target welding seam.

Abstract: In the automatic welding method and device for prestressed tubular piles provided in the present application, which is applied in welding equipment, a detection is conducted around a connection position between prestressed tubular piles and a position of a target welding seam is obtained. Then the target welding seam is welded around the prestressed tubular piles according to the position of the target welding seam.

Abstract: A retinoic acid modified lysosome targeting chimera (LYTAC) molecule, a preparation method and applications thereof are provided. A structural formula of the retinoic acid modified LYTAC molecule is shown as following Formula I, in which, n represents a molecular weight of polyethylene glycol (PEG), n is in a range of 60 to 5000, R is one of an antibody, a polypeptide and a micromolecule compound targeting a targeted protein. The retinoic acid modified LYTAC molecule can be applied to targeted protein degradation and preparation of tumor cell activity inhibitors. Retinoic acid has high biosafety, is easy to obtain and modify, can be coupled with any antibody, polypeptide or micromolecule that targets the binding protein receptor to realize lysosomal degradation of extracellular or membrane proteins, can be used to prepare tumor cell activity inhibitors and to treat tumors, inflammation and other diseases, and has a broad application prospect.

Abstract: Provided is an apparatus and method for detecting grout compactness in grouted splice sleeve, the apparatus comprises a probe assembly, which comprises at least one of capacitive probe and piezoelectric sensor and is arranged inside the grouted splice sleeve to detect parameters of the sleeve during grouting and curing and a detector, which comprises at least an analysis module that is connected with the probe assembly to obtain the detected parameters and carry out calculation and analysis for the parameters. The probe assembly is arranged inside the grouted splice sleeve and forms a loop with the detector during grouting, such that during the process of grouting, the detected parameters will be changed as the surrounding dielectric changes, therefore, the detector may determine in real time whether the grouted splice sleeve is fully grouted by calculating and analyzing the detected parameters, which achieves a faster and easier grout compactness detection.

Abstract: The disclosure provides for methods, compositions and kits that utilize total Oxidized phospholipids to determine whether a subject has liver disease.

Abstract: Provided is a drilling apparatus, comprising a PHC pipe cased pile having a drilling section for containing fluid and a hammer element arranged inside the cavity of the PHC pipe cased pile which moves along the drilling direction till the bottom of the drilling section. As the hammer element moves along the drilling direction till the bottom of the drilling section, a localized hydraulic force will be induced in the fluid contained in the drilling section of the PHC pipe cased pile by a sharp rise in the fluid pressure in addition to the impact force directly acted on the rock and soil by the hammer element. Under action of the hydraulic force and the impact force, the surrounding soft rock stratum could be crushed and the rock stratum with higher strength is left intact, that is, the drilling apparatus proceeds until harder rock. At this point, concrete casting will bond with the harder rock, resulting in a better bearing capacity of the PHC pipe cased pile foundation.

Abstract: Provided is a drilling apparatus, comprising a PHC pipe cased pile having a drilling section for containing fluid and a hammer element arranged inside the cavity of the PHC pipe cased pile which moves along the drilling direction till the bottom of the drilling section. As the hammer element moves along the drilling direction till the bottom of the drilling section, a localized hydraulic force will be induced in the fluid contained in the drilling section of the PHC pipe cased pile by a sharp rise in the fluid pressure in addition to the impact force directly acted on the rock and soil by the hammer element. Under action of the hydraulic force and the impact force, the surrounding soft rock stratum could be crushed and the rock stratum with higher strength is left intact, that is, the drilling apparatus proceeds until harder rock. At this point, concrete casting will bond with the harder rock, resulting in a better bearing capacity of the PHC pipe cased pile foundation.

Abstract: The present invention provides an epoxy resin material, a preparation method therefor and an application thereof. The present method for preparing an epoxy resin material comprises: heating a mixture of an epoxy resin main agent and a curing agent that are placed at room temperature to 40-85° C. for reaction and curing. The curing agent contains an adduct of an olefinic nitrile compound and an amine compound. The present method for preparing an epoxy resin material has the characteristics of low mixing viscosity, long operation time, and low amount of heat released during preparation.

Abstract: Provided is an apparatus and method for detecting grout compactness in grouted splice sleeve, the apparatus comprises a probe assembly, which comprises at least one of capacitive probe and piezoelectric sensor and is arranged inside the grouted splice sleeve to detect parameters of the sleeve during grouting and curing and a detector, which comprises at least an analysis module that is connected with the probe assembly to obtain the detected parameters and carry out calculation and analysis for the parameters. The probe assembly is arranged inside the grouted splice sleeve and forms a loop with the detector during grouting, such that during the process of grouting, the detected parameters will be changed as the surrounding dielectric changes, therefore, the detector may determine in real time whether the grouted splice sleeve is fully grouted by calculating and analyzing the detected parameters, which achieves a faster and easier grout compactness detection.

Abstract: The present invention provides an epoxy resin material, a preparation method therefor and an application thereof. The present method for preparing an epoxy resin material comprises: heating a mixture of an epoxy resin main agent and a curing agent that are placed at room temperature to 40-85° C. for reaction and curing. The curing agent contains an adduct of an olefinic nitrile compound and an amine compound. The present method for preparing an epoxy resin material has the characteristics of low mixing viscosity, long operation time, and low amount of heat released during preparation.

Abstract: A laser spectrometer includes a tunable laser assembly, a periodically-poled nonlinear optical crystal, with parallel polished input and output end faces, and a mechanism for controlling an entrance location of a pump input beam of the tunable laser on the input end face of the periodically-poled nonlinear optical crystal, such that the pump input beam traverses different grating periods of the periodically-poled nonlinear optical crystal.

Abstract: A laser beam expander has at least two negative lenses with adjustable collimation. The amount of required motion can be reduced by an order of magnitude over single negative lens approaches by splitting the input lens in two and adjusting the small remaining air gap between the lenses. The change in collimation may be accomplished by heating/cooling (i.e., thermal), mechanical motion (e.g., motors), electro-optical means (e.g., applying or reducing an electric current), any combination thereof, or any other suitable mechanism.

Abstract: A laser beam expander has at least two negative lenses with adjustable collimation. The amount of required motion can be reduced by an order of magnitude over single negative lens approaches by splitting the input lens in two and adjusting the small remaining air gap between the lenses. The change in collimation may be accomplished by heating/cooling (i.e., thermal), mechanical motion (e.g., motors), electro-optical means (e.g., applying or reducing an electric current), any combination thereof, or any other suitable mechanism.

Abstract: The present invention discloses a cellulose derivative shown as formula (I), which is obtained as follows: the hydroxyl at position 6 of microcrystalline cellulose is protected with triphenylchloromethane, and then reacted with acyl chloride or isocyanate. After the protection of the hydroxyl at positions 2 and 3 of microcrystalline cellulose, triphenylmethyl is removed under acidic conditions to expose the hydroxyl at position 6. Finally, the hydroxyl at position 6 is chiral derivatized with amino acid acyl chloride or polypeptide acyl chloride, to obtain a micro chiral regulation cellulose derivative. The micro chiral regulation cellulose derivative thus obtained is coated onto the surface of a silica gel support, to form a chiral stationary phase, which is filled in a stainless steel column to form a chiral column for the separation of various different types of chiral compounds. The preparation method of the present invention is not only efficient and convenient, but also safe and reliable.

Abstract: The present invention provides a bisamide-containing novel liquid chromatographic media and method of synthesizing the same. A novel polar bisamide functional group, which can form hydrogen bonds or ion pairs with residual silanols on the surface of silica gel, is used as the bonded phase on the surface of silica gel to better shield the activity of silanols and to eliminate the influence of residual silanol groups. Compared with conventional C18 columns, these novel bonded phases have different selectivity; they can work not only in 0 to 100% water but also in 0 to 100% organic mobile phase. In particular, they exhibit good peak shapes and resolutions for polar and basic compounds and have good stability within a very wide pH range. These properties make the new stationary phases a useful complement to conventional C18 columns for a variety of HPLC applications.

Abstract: The present invention provides a mail delivery method for a mobile terminal, which method comprises: a server sending a mail from a sender to a mobile terminal; and the mobile terminal displaying the mail at the time point set by the sender. The present invention further provides a mail system, which system comprises: a server for sending a mail from a sender to a mobile terminal; and the mobile terminal for displaying the mail at the time point set by the sender. The present invention solves the problem in the prior art, which is the fixed-time sending of the mail may be delayed, by means of fixed-time display, thus making the mail alert more punctual.