Abstract: A collision reaction pool ion acceleration apparatus which has extremely low crosstalk. The apparatus comprises an apparatus body, a vacuum chamber, a first tube bundle channel and a second tube bundle channel. The vacuum chamber is fixedly connected to the interior of the apparatus body; the other end of the interior of the apparatus body is fixedly connected to a first insulation seat. A collision chamber is embeddedly connected to the inside the first insulation seat, and a high-frequency electrode quadrupole lens is fixedly connected to two sides of the collision chamber. When charged ions enter the collision chamber, the high-frequency electrode quadrupole lens focuses on the charged ions, so that the incoming charged ions form a new motion trajectory in the collision chamber, and the charged ions are easily separated from the collision chamber, thereby increasing the working efficiency.

Abstract: A collision reaction pool ion acceleration apparatus which has extremely low crosstalk. The apparatus comprises an apparatus body, a vacuum chamber, a first tube bundle channel and a second tube bundle channel. The vacuum chamber is fixedly connected to the interior of the apparatus body; the other end of the interior of the apparatus body is fixedly connected to a first insulation seat. A collision chamber is embeddedly connected to the inside the first insulation seat, and a high-frequency electrode quadrupole lens is fixedly connected to two sides of the collision chamber. When charged ions enter the collision chamber, the high-frequency electrode quadrupole lens focuses on the charged ions, so that the incoming charged ions form a new motion trajectory in the collision chamber, and the charged ions are easily separated from the collision chamber, thereby increasing the working efficiency.

Abstract: The invention discloses a pretreatment method, a preservation method, an automatic treatment system and a detection method for a urine sample, and directs to the technical field of biological detection. The pretreatment method comprises subjecting a urine sample after protein lysis to a reductive alkylation treatment, followed by protein enrichment and enzymolysis. The protein enrichment is performed on the sample after the reductive alkylation treatment using a PVDF filter plate for protein enrichment; The invention also provides an automatic treatment system and an automatic sample treatment method. The treatment system greatly reduces the labor intensity of people, is beneficial to facilitate the treatment efficiency of urine sample treatment, meets the requirements of high-flux and automated pretreatment of the proteomics, and accommodates the reproducibility and flux of current clinical needs.

Abstract: The present disclosure provides a marker and use thereof in predicting a possibility of a subject with diabetes. The marker described may include at least one of ?-hydroxybutyric acid (?-HB), 1,5-anhydroglucitol (1,5-AG), asymmetric dimethylarginine (ADMA), cystine, ethanolamine, taurine, L-leucine, L-tryptophan, hydroxylysine, and L-aspartate. The possibility of the subject with diabetes may be predicted using a prediction model (e.g., prediction models 2-5) related to the marker based on a concentration of the marker. The prediction model 2 is related to ?-HB. The prediction model 3 is related to 1,5-AG and ADMA. The prediction model 4 is related to cystine, ethanolamine, taurine, L-leucine, L-tryptophan and hydroxylysine. The prediction model 5 is related to ?-HB, 1,5-AG, cystine, ethanolamine, taurine and L-aspartate.

Abstract: The embodiments of the present disclosure provide a method for analyzing a body fluid proteome. The method comprises: obtaining a sample to be tested I enriched with low-abundance proteins by removing high-abundance proteins in an initial sample A using an affinity technique; obtaining a sample to be tested II enriched with low-abundance proteins by removing high-abundance proteins in an initial sample B using chemical precipitation, wherein the initial sample A and the initial sample B are obtained from a same body fluid sample of a same subject; obtaining a proteome data set I by performing proteomic analysis on the sample to be tested I; obtaining a proteome data set II by performing proteomic analysis on the sample to be tested II; and determining a final quantified proteome data set of the body fluid sample based on the proteome data set I and the proteome data set II.

Abstract: The present disclosure provides a marker and use thereof in predicting a possibility of a subject with diabetes. The marker described may include at least one of ?-hydroxybutyric acid (?-HB), 1,5-anhydroglucitol (1,5-AG), asymmetric dimethylarginine (ADMA), cystine, ethanolamine, taurine, L-leucine, L-tryptophan, hydroxylysine, and L-aspartate. The possibility of the subject with diabetes may be predicted using a prediction model (e.g., prediction models 2-5) related to the marker based on a concentration of the marker. The prediction model 2 is related to ?-HB. The prediction model 3 is related to 1,5-AG and ADMA. The prediction model 4 is related to cystine, ethanolamine, taurine, L-leucine, L-tryptophan and hydroxylysine. The prediction model 5 is related to ?-HB, 1,5-AG, cystine, ethanolamine, taurine and L-aspartate.

Abstract: A light guide plate, a backlight module and a display device in the field of display technology are provided. The light guide plate includes a light guide plate body and a prism structure located at at least one end of the light guide plate body. The prism structure includes a light incident surface and at least one reflective surface, and incident light from the light incident surface is can be reflected by the at least one reflective surface into the light guide plate body.

Abstract: A single-surface position sensor and a positioning method thereof are disclosed.

Abstract: The present disclosure provides a display device, a manufacturing method thereof, a driving method thereof and a counter substrate. The display device includes a liquid crystal cell, at least one flicker detector and a signal processing apparatus. The at least one flicker detector is disposed in a non-display region within the liquid crystal cell and configured to detect light intensity in the liquid crystal cell; and the signal processing apparatus is configured to adjust a magnitude of a common voltage for driving the liquid crystal cell according to a signal strength outputted from the flicker detector, to reduce a flicker value of the display device.

Abstract: A substrate and a display device are disclosed. The substrate includes: a base substrate; a first temperature sensing section disposed on the base substrate; and a first processing chip connected with the first temperature sensing section. The substrate includes a peripheral area and a central area; one part of the first temperature sensing section is disposed in the peripheral area of the substrate; another part of the first temperature sensing section is disposed in the central area of the substrate; and the first processing chip is configured to convert temperature sensing signals of the central area and the peripheral area of the substrate sensed by the first temperature sensing section into relevant control signals and output the signals. The above first temperature sensing section can more accurately measure the temperature difference between the peripheral area and the central area of the substrate.

Abstract: A light guide plate, a backlight module and a display device in the field of display technology are provided. The light guide plate includes a light guide plate body and a prism structure located at at least one end of the light guide plate body. The prism structure includes a light incident surface and at least one reflective surface, and incident light from the light incident surface is can be reflected by the at least one reflective surface into the light guide plate body.

Abstract: A source drive circuit and a display device. The source drive circuit includes: a detection circuit, configure to detect a change value of a common voltage; and a compensation circuit, configured to obtain a compensation data signal based on a data signal and the change value of the common voltage, and output the compensation data signal to a pixel electrode of a display panel.

Abstract: A touch screen comprising a piezoelectric induction layer and an electric power collecting unit, wherein: the piezoelectric induction layer is configured to induct an external force to generate electric signals, and transmit the electric signals to the electric power collecting unit; and the electric power collecting unit is configured to process the electric signals and store electric power under driving of the electric signals. Thereby the problem of insufficient electric power of electronic device usually happened in being used is solved. A display screen, a display device and a method for storing electric power by using the display screen are further provided.

Abstract: Disclosed herein are methods, compositions and systems for analyzing and detecting enzyme activity. For examples, methods, compositions and systems for parallel detection and analysis of enzymatic activities of enzymes in complex biological mixtures are provided.

Abstract: A source drive circuit and a display device. The source drive circuit includes: a detection circuit, configure to detect a change value of a common voltage; and a compensation circuit, configured to obtain a compensation data signal based on a data signal and the change value of the common voltage, and output the compensation data signal to a pixel electrode of a display panel.

Abstract: A single-surface position sensor and a positioning method thereof are disclosed.

Abstract: The present disclosure provides a display device, a manufacturing method thereof, a driving method thereof and a counter substrate. The display device includes a liquid crystal cell, at least one flicker detector and a signal processing apparatus. The at least one flicker detector is disposed in a non-display region within the liquid crystal cell and configured to detect light intensity in the liquid crystal cell; and the signal processing apparatus is configured to adjust a magnitude of a common voltage for driving the liquid crystal cell according to a signal strength outputted from the flicker detector, to reduce a flicker value of the display device.

Abstract: A touch screen comprising a piezoelectric induction layer and an electric power collecting unit, wherein: the piezoelectric induction layer is configured to induct an external force to generate electric signals, and transmit the electric signals to the electric power collecting unit; and the electric power collecting unit is configured to process the electric signals and store electric power under driving of the electric signals. Thereby the problem of insufficient electric power of electronic device usually happened in being used is solved. A display screen, a display device and a method for storing electric power by using the display screen are further provided.

Abstract: A substrate and a display device are disclosed. The substrate includes: a base substrate; a first temperature sensing section disposed on the base substrate; and a first processing chip connected with the first temperature sensing section. The substrate includes a peripheral area and a central area; one part of the first temperature sensing section is disposed in the peripheral area of the substrate; another part of the first temperature sensing section is disposed in the central area of the substrate; and the first processing chip is configured to convert temperature sensing signals of the central area and the peripheral area of the substrate sensed by the first temperature sensing section into relevant control signals and output the signals. The above first temperature sensing section can more accurately measure the temperature difference between the peripheral area and the central area of the substrate.

Abstract: Described herein are methods, systems, and compositions for detecting enzyme activity. In some embodiments, the reaction product(s) are coupled with a mass tag, and the enzyme activity is determiner by analyzing the reaction product(s). The enzyme assays can be performed using mass spectrometry, for example nanostructure-initiator mass spectrometry (NIMS). Also described are methods, systems, and compositions for monitoring enzymatic degradation process of a substrate sample, for example a biomass.