Patents by Inventor Xiaoliang Sunney Xie

Xiaoliang Sunney Xie has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Single Cell Nucleic Acid Detection and Analysis
    Publication number: 20240117427
    Abstract: Methods and compositions for digital profiling of nucleic acid sequences present in a sample are provided.
    Type: Application
    Filed: December 4, 2023
    Publication date: April 11, 2024
    Inventors: Xiaoliang Sunney Xie, Katsuyuki Shiroguchi, Peter A. Sims, Tony Z. Jia
  • Single Cell Nucleic Acid Detection and Analysis
    Publication number: 20240093294
    Abstract: Methods and compositions for digital profiling of nucleic acid sequences present in a sample are provided.
    Type: Application
    Filed: November 28, 2023
    Publication date: March 21, 2024
    Inventors: Xiaoliang Sunney Xie, Katsuyuki Shiroguchi, Peter A. Sims, Tony Z. Jia
  • Single cell nucleic acid detection and analysis
    Patent number: 11866781
    Abstract: Methods and compositions for digital profiling of nucleic acid sequences present in a sample are provided.
    Type: Grant
    Filed: May 14, 2021
    Date of Patent: January 9, 2024
    Assignee: President and Fellows of Harvard College
    Inventors: Xiaoliang Sunney Xie, Katsuyuki Shiroguchi, Peter A. Sims, Tony Z. Jia
  • Single cell nucleic acid detection and analysis
    Patent number: 11834712
    Abstract: Methods and compositions for digital profiling of nucleic acid sequences present in a sample are provided.
    Type: Grant
    Filed: March 2, 2023
    Date of Patent: December 5, 2023
    Assignee: President and Fellows of Harvard College
    Inventors: Xiaoliang Sunney Xie, Katsuyuki Shiroguchi, Peter A. Sims, Tony Z. Jia
  • Single Cell Nucleic Acid Detection and Analysis
    Publication number: 20230212668
    Abstract: Methods and compositions for digital profiling of nucleic acid sequences present in a sample are provided.
    Type: Application
    Filed: March 2, 2023
    Publication date: July 6, 2023
    Inventors: Xiaoliang Sunney Xie, Katsuyki Shiroguchi, Peter A. Sims, Tony Z. Jia
  • Multiplex End-Tagging Amplification of Nucleic Acids
    Publication number: 20230203563
    Abstract: The present disclosure provides a method for assembly of genomic DNA using multiplex end-tagging amplification of genomic fragments.
    Type: Application
    Filed: November 14, 2022
    Publication date: June 29, 2023
    Inventors: Xiaoliang Sunney Xie, Dong Xing, Chi-Han Chang, Longzhi Tan
  • METHOD FOR PREPARING ANTIGEN-BINDING UNIT
    Publication number: 20230183322
    Abstract: A method for preparing an antibody, relating to the field of immunology and the field of molecular virology, in particular to the field of diagnosis, prevention and treatment of novel coronavirus. Specifically, provided are a monoclonal antibody against novel coronavirus, and a composition (e.g., a diagnostic agent and a therapeutic agent) containing the antibody. Also provided are the preparation, screening, and use of the antibody.
    Type: Application
    Filed: May 12, 2021
    Publication date: June 15, 2023
    Inventors: Xiaoliang Sunney XIE, Yunlong CAO, Wenjie SUN, Xu ZHANG
  • ANTI-NOVEL CORONAVIRUS MONOCLONAL ANTIBODY AND APPLICATION THEREOF
    Publication number: 20230174628
    Abstract: The present invention relates to the fields of immunology and molecular virology, and in particular, to the field of diagnosis, prevention and treatment of a novel coronavirus. Specifically, the present invention relates to an anti-novel coronavirus monoclonal antibody and a composition (for example, a diagnostic agent and a therapeutic agent) containing same. In addition, the present invention also relates to use of the antibody. The antibody of the present invention can be used for diagnosing, preventing and/or treating novel coronavirus infections and/or diseases (for example, novel coronavirus pneumonia) caused by the infections.
    Type: Application
    Filed: April 27, 2021
    Publication date: June 8, 2023
    Inventors: Xiaoliang Sunney XIE, Yunlong CAO, Wenjie SUN, Xu ZHANG
  • Single cell nucleic acid detection and analysis
    Patent number: 11629379
    Abstract: Methods and compositions for digital profiling of nucleic acid sequences present in a sample are provided.
    Type: Grant
    Filed: April 13, 2022
    Date of Patent: April 18, 2023
    Assignee: President and Fellows of Harvard College
    Inventors: Xiaoliang Sunney Xie, Katsuyuki Shiroguchi, Peter A. Sims, Tony Z. Jia
  • MONOCLONAL ANTIBODY AGAINST NOVEL CORONAVIRUS AND APPLICATION THEREOF
    Publication number: 20230116587
    Abstract: Provided are a monoclonal antibody against a novel coronavirus and a composition that comprises said antibody. The antibody can be used to diagnose, prevent and/or treat novel coronavirus infections and/or diseases caused by an infection.
    Type: Application
    Filed: March 12, 2021
    Publication date: April 13, 2023
    Inventors: Xiaoliang Sunney XIE, Yunlong CAO, Wenjie SUN
  • Single cell nucleic acid detection and analysis
    Patent number: 11608527
    Abstract: Methods and compositions for digital profiling of nucleic acid sequences present in a sample are provided.
    Type: Grant
    Filed: April 13, 2022
    Date of Patent: March 21, 2023
    Assignee: President and Fellows of Harvard College
    Inventors: Xiaoliang Sunney Xie, Katsuyuki Shiroguchi, Peter A. Sims, Tony Z. Jia
  • Multiplex end-tagging amplification of nucleic acids
    Patent number: 11530436
    Abstract: The present disclosure provides a method for assembly of genomic DNA using multiplex end-tagging amplification of genomic fragments.
    Type: Grant
    Filed: May 23, 2018
    Date of Patent: December 20, 2022
    Assignee: President and Fellows of Harvard College
    Inventors: Xiaoliang Sunney Xie, Dong Xing, Chi-Han Chang, Longzhi Tan
  • Single Cell Nucleic Acid Detection and Analysis
    Publication number: 20220259652
    Abstract: Methods and compositions for digital profiling of nucleic acid sequences present in a sample are provided.
    Type: Application
    Filed: April 13, 2022
    Publication date: August 18, 2022
    Inventors: Xiaoliang Sunney Xie, Katsuyuki Shiroguchi, Peter A. Sims, Tony Z. Jia
  • Single Cell Nucleic Acid Detection and Analysis
    Publication number: 20220251646
    Abstract: Methods and compositions for digital profiling of nucleic acid sequences present in a sample are provided.
    Type: Application
    Filed: April 13, 2022
    Publication date: August 11, 2022
    Inventors: Xiaoliang Sunney Xie, Katsuyuki Shiroguchi, Peter A. Sims, Tony Z. Jia
  • Single cell nucleic acid detection and analysis
    Patent number: 11352669
    Abstract: Methods and compositions for digital profiling of nucleic acid sequences present in a sample are provided.
    Type: Grant
    Filed: June 30, 2021
    Date of Patent: June 7, 2022
    Assignee: President and Fellows of Harvard College
    Inventors: Xiaoliang Sunney Xie, Katsuyuki Shiroguchi, Peter A. Sims, Tony Z. Jia
  • Single cell nucleic acid detection and analysis
    Patent number: 11286523
    Abstract: Methods and compositions for digital profiling of nucleic acid sequences present in a sample are provided.
    Type: Grant
    Filed: January 28, 2020
    Date of Patent: March 29, 2022
    Assignee: President and Fellows of Harvard College
    Inventors: Xiaoliang Sunney Xie, Katsuyuki Shiroguchi, Peter A. Sims, Tony Z. Jia
  • Single Cell Nucleic Acid Detection and Analysis
    Publication number: 20210381045
    Abstract: Methods and compositions for digital profiling of nucleic acid sequences present in a sample are provided.
    Type: Application
    Filed: August 24, 2021
    Publication date: December 9, 2021
    Inventors: Xiaoliang Sunney Xie, Katsuyuki Shiroguchi, Peter A. Sims, Tony Z. Jia
  • Single Cell Nucleic Acid Detection and Analysis
    Publication number: 20210324469
    Abstract: Methods and compositions for digital profiling of nucleic acid sequences present in a sample are provided.
    Type: Application
    Filed: June 30, 2021
    Publication date: October 21, 2021
    Inventors: Xiaoliang Sunney Xie, Katsuyuki Shiroguchi, Peter A. Sims, Tony Z. Jia
  • Methods of Whole Genome Digital Amplification
    Publication number: 20210285038
    Abstract: The present disclosure provides a method for genomic DNA amplification, such as whole genome amplification, including using a transposase system to make fragments of the genomic DNA including primer binding sites, isolating in oil each fragment within its own aqueous microdroplet along with PCR amplification reagents, amplifying each fragment within its own aqueous microdroplet, demulsifying the microdroplets to obtain the amplicons and sequencing the amplicons.
    Type: Application
    Filed: August 31, 2016
    Publication date: September 16, 2021
    Applicant: President and Fellows of Harvard College
    Inventors: Xiaoliang Sunney Xie, Dong Xing, Chi-Han Chang
  • Single Cell Nucleic Acid Detection and Analysis
    Publication number: 20210277466
    Abstract: Methods and compositions for digital profiling of nucleic acid sequences present in a sample are provided.
    Type: Application
    Filed: May 14, 2021
    Publication date: September 9, 2021
    Inventors: Xiaoliang Sunney Xie, Katsuyuki Shiroguchi, Peter A. Sims, Tony Z. Jia