Abstract: The present disclosure provides a method for methylation analysis of genomic fragments.

Abstract: Provided are a device, a system and a method for acquiring a force information based on a bionic structure, including: a force information acquisition layer and a magnetic field signal acquisition chip; wherein a permanent magnet is embedded in the force information acquisition layer; wherein the force information acquisition layer has an elastic structure configured to generate a deformation corresponding to a first force information of a force after being subjected to the force, so that the permanent magnet moves with the deformation to generate a magnetic field signal corresponding to the force information; wherein the magnetic field signal acquisition chip is arranged in parallel with the force information acquisition layer, and is configured to acquire the magnetic field signal and convert the magnetic field signal into an electrical signal.

Abstract: A vascular interventional instrument control device capable of operating double guide wires or balloons, includes a main finger assembly, a first sub-finger assembly, a second sub-finger assembly, a driving assembly and a clamping assembly, wherein the main finger assembly, the sub-finger assembly, the driving assembly and the clamping assembly are separately installed to the body structural member and separately connected to the controller through a communication link, one of the operated double guide wires or balloons is clamped by the main finger assembly and the first sub-finger assembly, and the other is clamped by the main finger assembly and the second sub-finger assembly; and the operated double guide wires or double balloons can be separately moved axially or rotated about its own axial direction.

Abstract: A vascular interventional instrument control device capable of operating double guide wires or balloons, includes a main finger assembly, a first sub-finger assembly, a second sub-finger assembly, a driving assembly and a clamping assembly, wherein the main finger assembly, the sub-finger assembly, the driving assembly and the clamping assembly are separately installed to the body structural member and separately connected to the controller through a communication link, one of the operated double guide wires or balloons is clamped by the main finger assembly and the first sub-finger assembly, and the other is clamped by the main finger assembly and the second sub-finger assembly; and the operated double guide wires or double balloons can be separately moved axially or rotated about its own axial direction.

Abstract: The application presents a multi-posture lower limb rehabilitation robot, which includes a robot base and a training bed. The training bed comprises two sets of leg mechanisms, a seat, a seat width adjustment mechanism, a mechanism for adjusting the gravity center of human body, a back cushion, a weight support system and a mechanism for adjusting the back cushion angle. The robot base comprises a mechanism for adjusting the bed angle. The mechanisms for adjusting the angles of bed and back cushion can be used together to provide paralysis patients with multiple training modes of lying, sitting, and standing postures. Each leg mechanism comprises hip, knee, and ankle joints, which are driven by electric motors; angle and force sensors are installed on each joint, and can be used to identify patients' motion intention to provide patients with active and assistant training.

Abstract: The present invention discloses an upper limb rehabilitation robot system comprising a computer (8) and a rehabilitation robot (7), wherein the computer (8) is used for performing information interaction (11) with the rehabilitation robot (7), recording training information, sending control command to the rehabilitation robot (7), showing the virtual training environment, providing rehabilitation training visual feedback (14), and showing the control interface and rehabilitation training information; wherein the rehabilitation robot (7), acting as a system actuator, is connected to the computer (8) for receiving the control command from the computer (8) to complete the motion control and terminal force output, and sending sensor data to the computer (8) at the same time.

Abstract: A catheter or guide wire manipulating device with two-point-clamping for vascular intervention is provided, comprising a thumb component (3), a forefinger component (4), a driving component (1) and a catheter/guide wire support component (2); the thumb component (3) comprises a pair of rollers (9, 10) configured to advance or retreat the catheter/guide wire; the thumb component (3) is configured to drive the catheter/guide wire to rotate clockwise or counterclockwise through a combination motion of the components; the forefinger component (4) is configured to implement the rotation and the advancement of the catheter/guide wire by moving manually away from the thumb component (3), and returning by a pull force of a spring (27) after being released; the driving component (2) is configured to drive the thumb component (3) and the forefinger component (4); the catheter/guide wire support component comprises a Y adapter fixation configured to install a Y adapter and an entry support configured to support and guid

Abstract: The application presents a multi-posture lower limb rehabilitation robot, which includes a robot base and a training bed. The training bed comprises two sets of leg mechanisms, a seat, a seat width adjustment mechanism, a mechanism for adjusting the gravity center of human body, a back cushion, a weight support system and a mechanism for adjusting the back cushion angle. The robot base comprises a mechanism for adjusting the bed angle. The mechanisms for adjusting the angles of bed and back cushion can be used together to provide paralysis patients with multiple training modes of lying, sitting, and standing postures. Each leg mechanism comprises hip, knee, and ankle joints, which are driven by electric motors; angle and force sensors are installed on each joint, and can be used to identify patients' motion intention to provide patients with active and assistant training.

Abstract: A catheter or guide wire manipulating device for vascular intervention is provided, comprising a thumb component (3), a forefinger component (4), a driving component (1) and a catheter/guide wire support component (2); the thumb component comprises a roller (7) configured to advance or retreat the catheter/guide wire; the thumb component (3) is configured to drive the catheter/guide wire to rotate clockwise or counterclockwise through a combination motion of the components; the forefinger component (4) is configured to cooperate with the thumb component (3) to implement the rotation and the advancement of the catheter/guide wire by moving manually away from the thumb component, and returning by a pull force of a spring (23) after being released; the driving component (1) is configured to drive the thumb component (3) and the forefinger component (4); the catheter/guide wire support component (2) comprises a Y adapter fixation configured to install a Y adapter and an entry support configured to support and gui

Abstract: The present invention discloses an upper limb rehabilitation robot system comprising a computer (8) and a rehabilitation robot (7), wherein the computer (8) is used for performing information interaction (11) with the rehabilitation robot (7), recording training information, sending control command to the rehabilitation robot (7), showing the virtual training environment, providing rehabilitation training visual feedback (14), and showing the control interface and rehabilitation training information; wherein the rehabilitation robot (7), acting as a system actuator, is connected to the computer (8) for receiving the control command from the computer (8) to complete the motion control and terminal force output, and sending sensor data to the computer (8) at the same time.

Abstract: A catheter or guide wire manipulating device with two-point-clamping for vascular intervention is provided, comprising a thumb component (3), a forefinger component (4), a driving component (1) and a catheter/guide wire support component (2); the thumb component (3) comprises a pair of rollers (9, 10) configured to advance or retreat the catheter/guide wire; the thumb component (3) is configured to drive the catheter/guide wire to rotate clockwise or counterclockwise through a combination motion of the components; the forefinger component (4) is configured to implement the rotation and the advancement of the catheter/guide wire by moving manually away from the thumb component (3), and returning by a pull force of a spring (27) after being released; the driving component (2) is configured to drive the thumb component (3) and the forefinger component (4); the catheter/guide wire support component comprises a Y adapter fixation configured to install a Y adapter and an entry support configured to support and guid

Abstract: A catheter or guide wire manipulating device for vascular intervention is provided, comprising a thumb component (3), a forefinger component (4), a driving component (1) and a catheter/guide wire support component (2); the thumb component comprises a roller (7) configured to advance or retreat the catheter/guide wire; the thumb component (3) is configured to drive the catheter/guide wire to rotate clockwise or counterclockwise through a combination motion of the components; the forefinger component (4) is configured to cooperate with the thumb component (3) to implement the rotation and the advancement of the catheter/guide wire by moving manually away from the thumb component, and returning by a pull force of a spring (23) after being released; the driving component (1) is configured to drive the thumb component (3) and the forefinger component (4); the catheter/guide wire support component (2) comprises a Y adapter fixation configured to install a Y adapter and an entry support configured to support and gui

Abstract: A microscopy or micro-spectroscopy system is disclosed that includes a first light source, a second light source, a modulator, an optical assembly and a processor. The first light source is for providing a first illumination field at a first optical frequency ?1 and the second light source is for providing a second illumination field at a second optical frequency ?2. The modulator is for modulating a property of the second illumination field at a modulation frequency f of at least 100 kHz to provide a modulated second illumination field. The optical assembly includes focusing optics and an optical detector system. The focusing optics is for directing and focusing the first illumination field and the modulated second illumination field through an objective lens toward the common focal volume along an excitation path.

Abstract: The invention provides a system and method for automatic real-time monitoring for the presence of a pathogen in water using coherent anti-stokes Raman scattering (CARS) microscopy. Water sample trapped in a trapping medium is provided to a CARS imager. CARS images are provided to a processor for automatic analyzing for the presence of image artifacts having pre-determined features characteristic to the pathogen. If a match is found, a CARS spectrum is taken and compared to a stored library of reference pathogen-specific spectra for pathogen identification. The system enables automatic pathogen detection in flowing water in real time.

Abstract: A system is disclosed for providing a first electromagnetic field and a second electromagnetic field to vibrational analysis equipment that is responsive to a difference between first and second frequencies of the first and second electromagnetic fields respectively. The system includes a non-linear crystal that may be pumped at a high repetition rate to provide a pulsed signal field at a signal field frequency and a pulsed idler field at an idler field frequency as output. The signal field provides the first electromagnetic field and the idler field provides the second electromagnetic field. The system also includes a tuning system for permitting the difference between the signal field frequency and the idler field frequency to be changed. The system also includes an output unit for providing the first and second electromagnetic fields to the vibrational analysis equipment.

Abstract: A system is disclosed for detecting a nonlinear coherent field induced in a sample. The system includes optics, a modulation system, and a detector system. The optics are for directing a first electromagnetic field at a first frequency ?1 and a second electromagnetic field at a second frequency ?2 toward a focal volume such that a difference frequency ?1??2 is resonant with a vibrational frequency of a sample in the focal volume. The modulation system is for modulating the difference frequency ?1??2 such that the difference frequency ?1??2 is tuned in and out of the vibrational frequency of the sample at a modulation frequency. The detector system is for detecting an optical field that is generated through non-linear interaction of ?1 and ?2 and the sample responsive to the modulation frequency.

Abstract: A system is disclosed for detecting a signal field from a sample volume. The system includes a source system and an optical fiber system. The source system provides a first electromagnetic field at a first frequency and a second electromagnetic field at a second frequency that is different from the first frequency. The optical fiber system includes at least one optical fiber for guiding the first and second electromagnetic fields to the sample volume to generate coherent radiation characteristic of molecular vibrations by non-linear interaction of the first and second fields with the sample volume. The optical fiber system also receives the signal field resulting from the coherent radiation, and guides the signal field to a detector.

Abstract: A system is disclosed for detecting a non-linear coherent field induced in a sample volume. The system includes a first source for generating a first electromagnetic field at a first frequency, a second source for generating a second electromagnetic field at a second frequency, first optics for directing the first and second electromagnetic fields toward the sample volume, second optics for directing the first and second electromagnetic fields toward a local oscillator volume, and an interferometer. The interferometer is for interfering a first scattering field that is generated by the interaction of the first and second electromagnetic fields in the sample volume, with a second scattering field that is generated by the interaction of the first and second electromagnetic fields in the local oscillator volume.