Abstract: Provided are a method for processing an OFDM signal, a system for transmitting an OFDM signal, and a device, which effectively reduce a peak to average power ratio of the OFDM signal.

Abstract: The present disclosure relates to the technical field of computer, and in particular, an information interaction method, device, electronic apparatus and storage medium. According to an embodiment of the present disclosure, there is provided an information interaction method, including: displaying a virtual reality space, the virtual reality space including a video image display space and a target message display space; displaying a video image in the video image display space; determining a target message and displaying the target message in the target message display space; wherein the target message display space is located in front of the video image display space in a first direction, the first direction being a direction toward which the video image faces.

Abstract: The present invention discloses a maleic anhydride modified voltage stabilizer, a preparation method, and use thereof, which belongs to the technical field of high voltage and insulation. The present invention discloses a maleic anhydride modified voltage stabilizer represented by Formula 1 and a preparation method thereof. (1) Maleic anhydride and 2,4-dihydroxybenzophenone are dissolved in tetrahydrofuran to obtain a mixture. (2) In a protective gas atmosphere, the mixture obtained in step (1) is added with a catalyst and stirred, centrifuged with added water, and an obtained precipitate is dried, thereby achieving the maleic anhydride modified voltage stabilizer. The present invention also provides the use of the maleic anhydride modified voltage stabilizer in a cross-linked polyethylene high voltage AC cable insulating material.

Abstract: Embodiments of the present disclosure relate to methods and kits for sequencing by synthesis utilizing biorthogonal chemical reactions between unlabeled nucleotides and post incorporation labeling reagents.

Abstract: Provided herein are methods of determining loss of heterozygosity in human leukocyte antigen in liquid biopsies and applications thereof in cancer treatment.

Abstract: The present disclosure relates to a virtual reality-based control method and apparatus, and an electronic device, and relates to the technical field of virtual reality. The method comprises: first monitoring image information captured by a camera for a user; identifying movement information of a target object in the image information; then, according to the movement information of the target object, displaying at least one interactive component model in a virtual reality space, and executing an interaction function event that is pre-bound to an interactive component model selected by the user. By means of applying the technical solution in the present disclosure, the technical problem that user control is easily influenced due to the buttons of an entity device being easily damaged can be effectively solved. A stronger technological sense can be brought to users, thereby enhancing the VR usage experience of users.

Abstract: Embodiments of the present disclosure relate to nucleotide molecules with a 3? AOM blocking group. Also provided herein are methods to prepare such nucleotide molecules, and the uses of fully functionalized nucleotides containing the 3?-OH blocking group for sequencing applications.

Abstract: The present invention relates to the technical field of medicinal chemistry, and particularly to a method for preparing a 3-tetrazolylmethyl-1,3,5-triazin-2,4-dione compound inhibiting coronavirus 3CL protease activity and use thereof. Specifically, a compound of Formula I, or a pharmaceutically acceptable salt, or an optical isomer, or an isotope-substituted form thereof is provided. The compound effectively inhibits the SARS-CoV-2 3CLpro activity, and is useful in the preparation of a SARS-CoV-2 3CLpro inhibitor to block the replication and transcription of SARS-CoV-2 viruses in patients. The compound prepared in the present invention has high in-vitro safety, and very good prospect of application in the preparation of SARS-CoV-2 3CLpro inhibitors and anti-SARS-CoV-2 drugs.

Abstract: A method for evaluating a degassing effect of a cross-linked polyethylene cable, includes: acquiring a cable sample to be detected; heating the cable sample to be detected; under a darkroom condition, acquiring at least one light spot image of said transparent cable sample under irradiation of a monochromatic laser light source; extracting light intensity data of the at least one light spot image in a preset light spot image range; normalizing the light intensity data, and obtaining the maximum value and an average value of normalized light intensity coefficients of said transparent cable sample in a preset thickness range of the insulating layer; calculating a degassing uniformity coefficient according to the maximum value and the average value; and obtaining an evaluation result of the degassing effect of the cross-linked polyethylene cable according to the maximum value, the average value, and the degassing uniformity coefficient.

Abstract: An information interaction method, an electronic device, and a storage medium are provided. The method includes: displaying a virtual reality space, the virtual reality space including a video image display space for displaying a video image; determining a target message in response to a message sending operation; determining a message movement start point of the target message based on the message sending operation; and moving the target message in the virtual reality space based on the message movement start point.

Abstract: Embodiments of the present disclosure relate to cyclooctatetraene containing dyes and their uses as fluorescent labels. Also provided are composition containing cyclooctatetraene. The dyes and compositions may be used in various biological applications, such as nucleic acid sequencing.

Abstract: Embodiments of the present disclosure relate to methods of preparation of templates for polynucleotide sequencing. In particular, the disclosure relates to linearization of clustered polynucleotides in preparation for sequencing by cleavage of one or more first strands of double-stranded polynucleotides immobilized on a solid support by a transition metal complex, for example, a palladium complex or a nickel complex. Further disclosure relate to linearization of clustered polynucleotides by cleaving one or more second strands of double double-stranded polynucleotides immobilized on a solid support comprising azobenzene linker by Na2S2O4. Nucleotides and oligonucleotides comprising a 3? phosphate moiety blocking group, and methods of removing the same using a fluoride reagent are also disclosed.

Abstract: Embodiments of the present application relates to methods and compositions for increasing fluorescent dye signal intensity during sequencing by synthesis. In particular, the compositions and methods described herein involve the use aqueous scan mixtures including one or more water-soluble macrocycles that can form host-guest complexes with the dyes.

Abstract: Automated methods conducted in a sequencing flowcell, and kits for reusing a flowcell, are provided herein. In some examples, an automated method conducted in a sequencing flowcell may include, at a surface of the sequencing flowcell coupled to a first moiety, using a reagent to decouple a first complex from the first moiety. In some examples, the first complex may include a second moiety which couples to the first moiety and a polynucleotide coupled to the second moiety. In some examples, the method may further include using a nuclease to polynucleotides in the sequencing flowcell. The method may include, after using the reagent and after using the nuclease, coupling a second complex to the first moiety. The second complex may include a third moiety which couples with the first moiety and an oligonucleotide coupled to the third moiety.

Abstract: Described herein are heterocyclic azide-containing monomer units, copolymers comprising such heterocyclic azide-containing monomer units, substrate-bound copolymers, and oligonucleotide-bound copolymers, methods for making such copolymers and reacting them with a substrate and/or oligonucleotide, and methods of using such copolymers for immobilization of oligonucleotides to a substrate, for example for use in DNA sequencing or other diagnostic applications.

Abstract: Embodiments of the present disclosure relate to methods of preparation of templates for polynucleotide sequencing. In particular, the disclosure relates to linearization of clustered polynucleotides in preparation for sequencing by cleavage of one or more first strands of double-stranded polynucleotides immobilized on a solid support by a transition metal complex, for example, a palladium complex or a nickel complex. Further disclosure relate to linearization of clustered polynucleotides by cleaving one or more second strands of double double-stranded polynucleotides immobilized on a solid support comprising azobenzene linker by Na2S2O4. Nucleotides and oligonucleotides comprising a 3? phosphate moiety blocking group, and methods of removing the same using a fluoride reagent are also disclosed.

Abstract: Embodiments of the present disclosure relates to various bisulfite-free chemical methods for detecting methylation of cytosine in the DNA sample. These methods convert methylated and hydroxymethylated cytosine in the nucleic acid sequence to a modified or pseudo thymine or a uracil moiety which then can be detected in sequencing.

Abstract: The present application relates to substituted coumarin derivatives and their uses as fluorescent labels. These compounds may be used as fluorescent labels for nucleotides in nucleic acid sequencing applications.

Abstract: Disclosed herein include methods, compositions, reaction mixtures, kits and systems for identification of methylated cytosines in nucleic acids using a bisulfite-free, one-step chemoenzymatic modification of methylated cytosines.

Abstract: Embodiments of the present disclosure relate to nucleotides with 3? allyl blocking groups. Also provided herein are methods of sequencing using nucleotides with 3? allyl blocking groups described herein, and sequencing kits.