Patents by Inventor Xiaolin Wu

Xiaolin Wu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10336931
    Abstract: The present invention relates to the well drilling field in petrochemical industry, in particular to use of dual-cation fluorocarbon surfactant as amphiphobic wettability reversal agent in drilling fluid. The dual-cation fluorocarbon surfactant is a dual-cation fluorocarbon surfactant of which the cation part is represented by the following formula (1). The dual-cation fluorocarbon surfactant of the present invention can serve as wettability reversal agent when it is used for oil-gas drilling to enable rock amphiphobic, and is an amphiphobic wettability reversal agent which can cause rock surface to be non-hydrophilic and non-lipophilic. Using of dual-cation fluorocarbon surfactant, especially when drilling highly hydrous mud shale, can avoid permeation of water and oil into the rock effectively and thereby a capillary phenomenon can be prevented, and an effect of stabilizing the well wall and protecting the reservoir is attained.
    Type: Grant
    Filed: January 18, 2018
    Date of Patent: July 2, 2019
    Assignee: CHINA UNIVERSITY OF PETROLEUM (BEIJING)
    Inventors: Guancheng Jiang, Deli Gao, Guangchang Ma, Jinsheng Sun, Xi Wang, Xiaolin Pu, Xianzhu Wu, Xiaoxiao Ni, Xianmin Zhang, Le Wang, Yinbo He, Fan Liu, Lili Yang, Tengfei Dong
  • Publication number: 20190197786
    Abstract: A method to efficiently update and manage outputs of real time or offline 3D reconstruction and scanning in a mobile device having limited resource and connection to the Internet is provided. The method makes available to a wide variety of mobile XR applications fresh, accurate and comprehensive 3D reconstruction data, in either single user applications or multi-user applications sharing and updating the same 3D reconstruction data. The method includes a block-based 3D data representation that allows local update and maintains neighbor consistency at the same time, and a multi-layer caching mechanism that retrieves, prefetches, and stores 3D data efficiently for XR applications.
    Type: Application
    Filed: December 21, 2018
    Publication date: June 27, 2019
    Applicant: Magic Leap, Inc.
    Inventors: David Geoffrey Molyneaux, Frank Thomas Steinbrücker, Zhongle Wu, Xiaolin Wei, Jianyuan Min, Yifu Zhang
  • Publication number: 20190197777
    Abstract: A method to culling parts of a 3D reconstruction volume is provided. The method makes available to a wide variety of mobile XR applications fresh, accurate and comprehensive 3D reconstruction data with low usage of computational resources and storage spaces. The method includes culling parts of the 3D reconstruction volume against a depth image. The depth image has a plurality of pixels, each of which represents a distance to a surface in a scene. In some embodiments, the method includes culling parts of the 3D reconstruction volume against a frustum. The frustum is derived from a field of view of an image sensor, from which image data to create the 3D reconstruction is obtained.
    Type: Application
    Filed: December 21, 2018
    Publication date: June 27, 2019
    Applicant: Magic Leap, Inc.
    Inventors: Frank Thomas Steinbrücker, David Geoffrey Molyneaux, Zhongle Wu, Xiaolin Wei, Jianyuan Min, Yifu Zhang
  • Publication number: 20190197774
    Abstract: A method of operating a computing system to generate a model of an environment represented by a mesh is provided. The method allows to update 3D meshes to client applications in real time with low latency to support on the fly environment changes. The method provides 3D meshes adaptive to different levels of simplification requested by various client applications. The method provides local update, for example, updating the mesh parts that are changed since last update. The method also provides 3D meshes with planarized surfaces to support robust physics simulations. The method includes segmenting a 3D mesh into mesh blocks. The method also includes performing a multi-stage simplification on selected mesh blocks. The multi-stage simplification includes a pre-simplification operation, a planarization operation, and a post-simplification operation.
    Type: Application
    Filed: December 21, 2018
    Publication date: June 27, 2019
    Applicant: Magic Leap, Inc.
    Inventors: David Geoffrey Molyneaux, Frank Thomas Steinbrücker, Zhongle Wu, Xiaolin Wei, Jianyuan Min, Yifu Zhang
  • Publication number: 20190197765
    Abstract: An augmented reality/mixed reality system that provides a more immersive user experience. That experience is provided with increased speed of update for occlusion data by using depth sensor data augmented with lower-level reconstruction data. When operating in real-time dynamic environments, changes in the physical world can be reflected quickly in the occlusion data. Occlusion rendering using live depth data augmented with lower-level 3D reconstruction data, such as a raycast point cloud, can greatly reduce the latency for visual occlusion processing. Generating occlusion data in this way may provide faster operation of an XR system using less computing resources and enabling the system to be packaged in a battery operated wearable device.
    Type: Application
    Filed: December 21, 2018
    Publication date: June 27, 2019
    Applicant: Magic Leap, Inc.
    Inventors: David Geoffrey Molyneaux, Frank Thomas Steinbrücker, Zhongle Wu, Xiaolin Wei, Jianyuan Min, Yifu Zhang
  • Publication number: 20190185502
    Abstract: There are provided compounds of Formula (A) and pharmaceutically acceptable salts and esters thereof, and pharmaceutical compositions thereof, used for the prevention or treatment in a mammal of joint and bone disorders such as arthritis and osteoporosis.
    Type: Application
    Filed: December 17, 2018
    Publication date: June 20, 2019
    Inventors: Jiasheng LU, Jiamin GU, Xiang JI, Daiqiang HU, Xiuchun ZHANG, Xinyong LV, Jinchao AI, Dongdong WU, Xianqi KONG, Lin WANG, Dongqing ZHU, Xiaolin HE
  • Patent number: 10307396
    Abstract: A pharmaceutical composition. The pharmaceutical composition is prepared from the following raw materials in parts by weight: 8.75-60 parts of silybin, 15-65 parts of phospholipid, 25-200 parts of a Pu'er tea extract, 6.25-40 parts of vitamin E, and 8.3-60 parts of L-carnitine. The composition can be used for treating non-alcoholic fatty liver diseases.
    Type: Grant
    Filed: March 22, 2016
    Date of Patent: June 4, 2019
    Assignee: Tasly Pharmaceutical Group Co., Ltd.
    Inventors: He Sun, Xijun Yan, Naifeng Wu, Kaijing Yan, Yonghong Zhu, Shunnan Zhang, Xiaolin Bai, Xiaohui Ma, Yi He, Ting Li, Lei Li
  • Patent number: 10307395
    Abstract: A pharmaceutical composition for treating non-alcoholic fatty liver diseases. The pharmaceutical composition is prepared from 8.75-60 parts by weight of silybin, 15-65 parts by weight of phospholipid, 25-150 parts by weight of a Pu'er tea extract, and 10.425-60 parts by weight of L-carnitine.
    Type: Grant
    Filed: March 22, 2016
    Date of Patent: June 4, 2019
    Assignee: Tasly Pharmaceutical Group Co., Ltd.
    Inventors: He Sun, Xijun Yan, Naifeng Wu, Kaijing Yan, Yonghong Zhu, Shunnan Zhang, Xiaolin Bai, Xiaohui Ma, Yi He, Ting Li, Lei Li
  • Publication number: 20190150896
    Abstract: The present invention provides a method and a system for medical imaging and information display. According to an aspect of the present invention, there is proposed a method of medical imaging and information display, comprising: acquiring imaging data of each point of a plurality of points in an imaging plane or imaging volume of a subject in each mode of a plurality of different imaging modes of a medical imaging apparatus; deriving, for said each point, a value by applying the imaging data of the point in said each mode and the imaging data of at least one other point of said plurality of points adjacent to the point in said each mode to a predetermined model, wherein the predetermined model is selected in accordance with a clinical medical application related to the subject; constructing an image based on all the derived values; and displaying the constructed image to a user.
    Type: Application
    Filed: January 25, 2019
    Publication date: May 23, 2019
    Inventors: Yinhui Deng, Xiaomin Li, Xiaolin Gu, Vijay Thakur Shamdasani, Ying Wu
  • Publication number: 20190153529
    Abstract: Some embodiments of the present application relate to novel modified nucleotide linkers for increasing the efficiency of nucleotide incorporation in Sequencing by Synthesis applications. Methods of preparing these modified nucleotide linkers are also provided herewith.
    Type: Application
    Filed: January 25, 2019
    Publication date: May 23, 2019
    Inventors: Xiaolin Wu, Xiaohai Liu
  • Patent number: 10287629
    Abstract: The present disclosure provides methods and systems for detecting multiple different nucleotides in a sample. In particular, the disclosure provides for detection of multiple different nucleotides in a sample utilizing fewer detection moieties than the number of nucleotides being detected and/or fewer imaging events than the number of nucleotides being detected.
    Type: Grant
    Filed: July 12, 2016
    Date of Patent: May 14, 2019
    Assignee: Illumina, Inc.
    Inventors: Robert C. Kain, Xiaohai Liu, Wenyi Feng, Bernard Hirschbein, Helmy A. Eltoukhy, Xiaolin Wu, Geoffrey Paul Smith, Jonathan Mark Boutell, Thomas Joseph, Randall Smith, Min-Jui Richard Shen, Carolyn Tregidgo, Kay Klausing
  • Patent number: 10239909
    Abstract: The present disclosure relates to new compounds and their use as fluorescent labels. The compounds may be used as fluorescent labels for nucleotides in nucleic acid sequencing applications. The labels are advantageous due to their long Stokes shifts.
    Type: Grant
    Filed: May 23, 2016
    Date of Patent: March 26, 2019
    Assignee: Illumina Cambridge Limited
    Inventors: Nikolai Romanov, Xiaolin Wu
  • Patent number: 10190157
    Abstract: Some embodiments of the present application relate to novel modified nucleotide linkers for increasing the efficiency of nucleotide incorporation in Sequencing by Synthesis applications. Methods of preparing these modified nucleotide linkers are also provided herewith.
    Type: Grant
    Filed: August 7, 2015
    Date of Patent: January 29, 2019
    Assignee: Illumina Cambridge Limited
    Inventors: Xiaolin Wu, Xiaohai Liu
  • Publication number: 20180353926
    Abstract: The invention relates to methods of generating templates for a nucleic acid sequencing reaction which comprise: providing at least one double-stranded nucleic acid molecule, wherein both strands of the double-stranded nucleic acid molecule are attached to a solid support at the 5? end, cleaving one or both strands of the double-stranded nucleic acid molecule, and subjecting the cleaved strand(s) to denaturing conditions to remove the portion of the cleaved strand(s) not attached to the solid support, thereby generating a partially or substantially single-stranded template for a nucleic acid sequencing reaction.
    Type: Application
    Filed: June 18, 2018
    Publication date: December 13, 2018
    Applicant: Illumina Cambridge Limited
    Inventors: Xiaohai Liu, John Milton, Geoffrey Paul Smith, Colin Lloyd Barnes, Isabelle Rasolonjatovo, Roberto Rigatti, Xiaolin Wu, Tobias William Barr Ost, Graham John Worsley, David James Earnshaw, Gerardo Turcatti, Anthony Romieu
  • Patent number: 10138514
    Abstract: Some embodiments described herein relate to modified nucleotide and nucleoside molecules with novel 3?-hydroxy protecting groups. Also provided herein are methods to prepare such modified nucleotide and nucleoside molecules and sequencing by synthesis processes using such modified nucleotide and nucleoside molecules.
    Type: Grant
    Filed: February 28, 2017
    Date of Patent: November 27, 2018
    Assignee: Illumina Cambridge Limited
    Inventors: Xiaohai Liu, Xiaolin Wu, Geoffrey Paul Smith
  • Patent number: 9999866
    Abstract: The invention relates to methods of generating templates for a nucleic acid sequencing reaction which comprise: providing at least one double-stranded nucleic acid molecule, wherein both strands of the double-stranded nucleic acid molecule are attached to a solid support at the 5? end, cleaving one or both strands of the double-stranded nucleic acid molecule, and subjecting the cleaved strand(s) to denaturing conditions to remove the portion of the cleaved strand(s) not attached to the solid support, thereby generating a partially or substantially single-stranded template for a nucleic acid sequencing reaction.
    Type: Grant
    Filed: October 6, 2016
    Date of Patent: June 19, 2018
    Assignee: ILLUMINA CAMBRIDGE LIMITED
    Inventors: Xiaohai Liu, John Milton, Geoffrey Paul Smith, Colin Lloyd Barnes, Isabelle Rasolonjatovo, Roberto Rigatti, Xiaolin Wu, Tobias William Barr Ost, Graham John Worsley, David James Earnshaw, Gerardo Turcatti, Anthony Romieu
  • Publication number: 20180155810
    Abstract: An ultra-heavy steel plate with low cracking sensitivity and low yield ratio, the mass percentages of chemical components of the steel plate are C 0.05-0.09; Si 0.2-0.4; Mn 1.3-1.6; Al 0.02-0.04; Nb 0.03-0.08; V 0.03-0.08; Cr 0.1-0.5; Ni 0.1-0.5; Mo 0.1-0.3; Cu 0.2-0.5; Ti 0.01-0.02; P?0.015; S?0.003; N?0.007, the balance being Fe and inevitable impurities; the carbon equivalent is ?0.43, the cold cracking sensitivity coefficient Pcm is ?0.20. A low cracking sensitivity and low yield ratio steel plate with a thickness of 40-70 mm is manufactured by the process steps of KR molten iron pretreatment-converter smelting-LF refining-RH vacuum degassing-continuous casting-lid-covering slow cooling for the continuous casting slabs-casting slabs heating-controlled rolling-controlled cooling-hot straightening-air cooling and so on.
    Type: Application
    Filed: October 19, 2016
    Publication date: June 7, 2018
    Inventors: Xianjin SUN, Zhuzhong GAO, Jianguo HU, Jingtao LI, Pifeng MIAO, Xiaolin WU, Ailai SHI, Fu ZHAO, Feng XU, Shouyu FANG
  • Publication number: 20180111957
    Abstract: The present disclosure relates to new compounds and their use as fluorescent labels. The compounds may be used as fluorescent labels for nucleotides in nucleic acid sequencing applications. The labels are advantageous due to their long Stokes shifts.
    Type: Application
    Filed: May 23, 2016
    Publication date: April 26, 2018
    Inventors: Nikolai Romanov, Xiaolin Wu
  • Patent number: 9802147
    Abstract: A filter tube for high temperature gas-solid separation is provided that has a first cylinder and a second cylinder coaxially nested in the first cylinder with the first cylinder arranged so that an opening thereof faces upward, a first connection flange provided at a periphery of the opening of the first cylinder, and a circular through-hole provided at a bottom of the first cylinder. The second cylinder is nested in the first cylinder so that an opening of the second cylinder faces downward. The second cylinder has an end at an opening thereof that is hermetically connected to the circular through-hole of the first cylinder. The second cylinder has a bottom, and the bottom of the second cylinder and the opening of the first cylinder are at the same horizontal level. An annular gas passage is formed between the first cylinder and the second cylinder.
    Type: Grant
    Filed: January 18, 2013
    Date of Patent: October 31, 2017
    Assignee: CHINA UNIVERSITY OF PETROLEUM—BEIJING
    Inventors: Zhongli Ji, Xiaolin Wu, Honghai Chen, Liang Yang, Zhiyi Xiong
  • Publication number: 20170166961
    Abstract: Some embodiments described herein relate to modified nucleotide and nucleoside molecules with novel 3?-hydroxy protecting groups. Also provided herein are methods to prepare such modified nucleotide and nucleoside molecules and sequencing by synthesis processes using such modified nucleotide and nucleoside molecules.
    Type: Application
    Filed: February 28, 2017
    Publication date: June 15, 2017
    Inventors: Xiaohai Liu, Xiaolin Wu, Geoffrey Paul Smith