Abstract: Provided are methods of using bromodomain-containing protein 9 inhibitor (I-BRD9) or a derivative thereof in preparation of anti-epileptic drugs. The I-BRD9 has significant effects on anticonvulsion, prolonging of convulsion latency, and reduction of seizure level, and can be used for preparing anti-epileptic drug preparations.

Abstract: Provided are methods of using bromodomain-containing protein 9 inhibitor (I-BRD9) or a derivative thereof in preparation of anti-epileptic drugs. The I-BRD9 has significant effects on anticonvulsion, prolonging of convulsion latency, and reduction of seizure level, and can be used for preparing anti-epileptic drug preparations.

Abstract: A novel passive control technique for laminar flow over air transportation vehicles and space reentry vehicles flying at high supersonic and hypersonic speeds is disclosed. The control of laminar flow can be achieved by applying an array of surface roughness elements in the region before the laminar-turbulent transition. For example, an array of two-dimensional rings, stripes, or closely packed three-dimensional isolated roughness elements may be used to stabilize the instability waves and delay transition. The roughness elements may have a height between 40% and 60% of the local boundary-layer thickness. The exact location, height, and spacing of surface roughness elements may be determined by a numerical simulation strategy based on the most unstable second mode, e.g. using known eN transition prediction method, experimental measurement, or any other suitable technique.

Abstract: A novel passive control technique for laminar flow over air transportation vehicles and space reentry vehicles flying at high supersonic and hypersonic speeds is disclosed. The control of laminar flow can be achieved by applying an array of surface roughness elements in the region before the laminar-turbulent transition. For example, an array of two-dimensional rings, stripes, or closely packed three-dimensional isolated roughness elements may be used to stabilize the instability waves and delay transition. The roughness elements may have a height between 40% and 60% of the local boundary-layer thickness. The exact location, height, and spacing of surface roughness elements may be determined by a numerical simulation strategy based on the most unstable second mode, e.g. using known eN transition prediction method, experimental measurement, or any other suitable technique.