Abstract: Disclosed are a polyethylene glycol conjugate drug, and a preparation method therefor and the use thereof. Specifically, the present invention relates to a polyethylene glycol conjugate drug represented by formula A or a pharmaceutically acceptable salt thereof, a method for preparing the polyethylene glycol conjugate drug or the pharmaceutically acceptable salt thereof, an intermediate for preparing the polyethylene glycol conjugate drug or the pharmaceutically acceptable salt thereof, a pharmaceutical composition comprising the polyethylene glycol conjugate drug or the pharmaceutically acceptable salt thereof, and the use of the polyethylene glycol conjugate drug or the pharmaceutically acceptable salt thereof in the preparation of a drug.

Abstract: An “outboard pontoon” semisubmersible floating platform for the use of offshore applications has a hull configuration including vertical deck support columns and a horizontally disposed pontoon structure. The vertical columns support the deck structure at upper ends and adjoin pontoon at their lower ends. Under the premise of ensuring platform stability, structural feasibility, and structural cost efficiency, the pontoon is horizontally extrapolated as far as possible radially outward from platform center in the horizontal plan while the elevation of the bottom of columns ranges anywhere from the pontoon bottom to the top surface of the pontoon. The vertical columns are adjoined to the pontoon from its inner periphery and the central vertical axis of each column resides a distance inward from the closest point of the center line of the pontoon. This arrangement makes part of pontoon become the “outboard pontoon” which is the important concept introduced by this invention.

Abstract: Described herein are systems, methods, and instrumentalities associated with segmenting and/or determining the shape of an anatomical structure. An artificial neural network (ANN) is used to perform these tasks based on a statistical shape model of the anatomical structure. The ANN is trained by evaluating and backpropagating multiple losses associated with shape estimation and segmentation mask generation. The model obtained using these techniques may be used for different clinical purposes including, for example, motion estimation and motion tracking.

Abstract: A data source simulation platform includes: a transmitting side and a receiving side. The transmitting side includes a parameter initializing module, a parameter calculation module, and a subframe data module. The receiving side includes a system function configuration module, a downlink initial synchronization module, an error control module, a time-frequency estimation module, and a data parsing module. The parameter initializing module is configured to construct simulation parameters, configure a subframe structure, and simulate a raw data block to be transmitted from a protocol data unit packet of a media access control layer to a physical layer. The parameter calculation module is configured to calculate set simulation parameters. The subframe data module is configured to provide independent data for an air-interface monitoring device, the data being in a modular design and independently corresponding to each submodule.

Abstract: A wearable robotic device for the rehabilitation training of a limb with moisture and pressure management functions. Such wearable robotic device comprises a motor rotation system and a bracing system, wherein the motor rotation system comprises a motor and a motor control system; and the bracing system comprises a framework of structural members that is attachable to and detachable from the limb, one or more textile bracing cushions and one or more fastening belts attached to each of the textile bracing cushions such that the fastening belts and the textile bracing cushions in combination are capable of attaching the wearable robotic device onto the limb.

Abstract: A head-mountable EEG electrode-containing device is provided based on radially adjustable electrodes to fit the wearer's unique head size and shape. The head-mountable device with an electrode array positioned therein includes multiple head-mountable device sections that are interconnected by mechanical fasteners to facilitate sizing and positioning of the head-mountable device. An array of resilient sleeves is positioned within each head-mountable device section. Each resilient sleeve houses an individual electrode and is deformable for self-orienting. The deformation of the sleeve is such that a central axis passing through the individual electrode housed within the resilient sleeve is maintained in a position approximately normal to a plane tangential to a scalp portion positioned beneath that electrode.

Abstract: A head-mountable EEG electrode-containing device is provided based on radially adjustable electrodes to fit the wearer's unique head size and shape. The head-mountable device with an electrode array positioned therein includes multiple head-mountable device sections that are interconnected by mechanical fasteners to facilitate sizing and positioning of the head-mountable device. An array of resilient sleeves is positioned within each head-mountable device section. Each resilient sleeve houses an individual electrode and is deformable for self-orienting. The deformation of the sleeve is such that a central axis passing through the individual electrode housed within the resilient sleeve is maintained in a position approximately normal to a plane tangential to a scalp portion positioned beneath that electrode.

Abstract: This invention relates to the fields of microbiology and antibiotics. Particularly, it relates to a new mutant strain, a method of its mutation breeding, to a monocomponent Gentamicin C.sub.1a produced by this strain which is used as mother nucleus of semisynthetic antibiotic 1-N-ethylgentamicin C.sub.1a, and to compositions composed of semisynthetic 1-N-ethylgentamicin derivatives as active component and pharmaceutically acceptable accitives and their manufacturing methods.