Abstract: An artificial blood vessel and a method for preparing the same are disclosed. The method includes: weaving warp yarns and weft yarns to form interlaced first and second weaves, both weaves extend along a weft direction and alternate to obtain a composite fabric; and successively corrugating and thermal-setting the composite fabric to obtain the artificial blood vessel. In the composite structure of the artificial blood vessel with the alternating the first and second weaves formed by the warp and weft yarns, a softness degree of the first weave is lower than that of the second weave. As a result, combining stiffness of the first weave with softness of the second weave, this composite structure ensures both low permeability and increased softness of the fabric. Therefore, it is improved to a certain extent over the conventional woven artificial blood vessels and is easier to handle and suture.