Patents by Inventor Xiaomei Jin
Xiaomei Jin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10093923Abstract: Provided herein are compositions, methods and kits for modulating expression of target genes, particularly heat shock protein 47 (hsp47). The compositions, methods and kits may include nucleic acid molecules (for example, short interfering nucleic acid (siNA), short interfering RNA (siRNA), double-stranded RNA (dsRNA), micro-RNA (miRNA) or short hairpin RNA (shRNA)) that modulate a gene encoding hsp47, for example, the gene encoding human hsp47. The composition and methods disclosed herein may also be used in treating conditions and disorders associated with hsp47 such as liver fibrosis, pulmonary fibrosis, peritoneal fibrosis and kidney fibrosis.Type: GrantFiled: October 27, 2015Date of Patent: October 9, 2018Assignee: NITTO DENKO CORPORATIONInventors: Xiaomei Jin, Lei Yu, Hirokazu Takahashi, Yasunobu Tanaka, Yoshiro Niitsu, Elena Feinstein, Sharon Avkin-Nachum, Hagar Kalinski, Igor Mett, Shai Erlich, Elizabeth C Squiers, Ning Chen
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Publication number: 20160108399Abstract: Provided herein are compositions, methods and kits for modulating expression of target genes, particularly heat shock protein 47 (hsp47). The compositions, methods and kits may include nucleic acid molecules (for example, short interfering nucleic acid (siNA), short interfering RNA (siRNA), double-stranded RNA (dsRNA), micro-RNA (miRNA) or short hairpin RNA (shRNA)) that modulate a gene encoding hsp47, for example, the gene encoding human hsp47. The composition and methods disclosed herein may also be used in treating conditions and disorders associated with hsp47 such as liver fibrosis, pulmonary fibrosis, peritoneal fibrosis and kidney fibrosis.Type: ApplicationFiled: October 27, 2015Publication date: April 21, 2016Applicant: NITTO DENKO CORPORATIONInventors: Xiaomei JIN, Lei YU, Hirokazu TAKAHASHI, Yasunobu TANAKA, Yoshiro NIITSU, Elena FEINSTEIN, Sharon AVKIN-NACHUM, Hagar KALINSKI, Igor METT, Shai ERLICH, Elizabeth C. SQUIERS, Ning CHEN
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Patent number: 9206424Abstract: Provided herein are compositions, methods and kits for modulating expression of target genes, particularly heat shock protein 47 (hsp47). The compositions, methods and kits may include nucleic acid molecules (for example, short interfering nucleic acid (siNA), short interfering RNA (siRNA), double-stranded RNA (dsRNA), micro-RNA (miRNA) or short hairpin RNA (shRNA)) that modulate a gene encoding hsp47, for example, the gene encoding human hsp47. The composition and methods disclosed herein may also be used in treating conditions and disorders associated with hsp47 such as liver fibrosis, pulmonary fibrosis, peritoneal fibrosis and kidney fibrosis.Type: GrantFiled: March 18, 2014Date of Patent: December 8, 2015Assignee: NITTO DENKO CORPORATIONInventors: Xiaomei Jin, Lei Yu, Hirokazu Takahashi, Yasunobu Tanaka, Yoshiro Niitsu, Elena Feinstein, Sharon Avkin-Nachum, Hagar Kalinski, Igor Mett, Shai Erlich, Elizabeth C Squiers, Ning Chen
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Publication number: 20140235695Abstract: Provided herein are compositions, methods and kits for modulating expression of target genes, particularly heat shock protein 47 (hsp47). The compositions, methods and kits may include nucleic acid molecules (for example, short interfering nucleic acid (siNA), short interfering RNA (siRNA), double-stranded RNA (dsRNA), micro-RNA (miRNA) or short hairpin RNA (shRNA)) that modulate a gene encoding hsp47, for example, the gene encoding human hsp47. The composition and methods disclosed herein may also be used in treating conditions and disorders associated with hsp47 such as liver fibrosis, pulmonary fibrosis, peritoneal fibrosis and kidney fibrosis.Type: ApplicationFiled: March 18, 2014Publication date: August 21, 2014Inventors: Xiaomei JIN, Lei YU, Hirokazu TAKAHASHI, Yasunobu TANAKA, Yoshiro NIITSU, Elena FEINSTEIN, Sharon AVKIN-NACHUM, Hagar KALINSKI, Igor METT, Shai ERLICH, Elizabeth C SQUIERS, Ning CHEN
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Patent number: 8710209Abstract: Provided herein are compositions, methods and kits for modulating expression of target genes, particularly heat shock protein 47 (hsp47). The compositions, methods and kits may include nucleic acid molecules (for example, short interfering nucleic acid (siNA), short interfering RNA (siRNA), double-stranded RNA (dsRNA), micro-RNA (miRNA) or short hairpin RNA (shRNA)) that modulate a gene encoding hsp47, for example, the gene encoding human hsp47. The composition and methods disclosed herein may also be used in treating conditions and disorders associated with hsp47 such as liver fibrosis, pulmonary fibrosis, peritoneal fibrosis and kidney fibrosis.Type: GrantFiled: December 8, 2010Date of Patent: April 29, 2014Assignee: Nitto Denko CorporationInventors: Xiaomei Jin, Lei Yu, Hirokazu Takahashi, Yasunobu Tanaka, Yoshiro Niitsu, Elena Feinstein, Sharon Avkin-Nachum, Hagar Kalinski, Igor Mett, Shai Erlich, Elizabeth C. Squiers, Ning Chen
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Publication number: 20110178157Abstract: Provided herein are compositions, methods and kits for modulating expression of target genes, particularly heat shock protein 47 (hsp47). The compositions, methods and kits may include nucleic acid molecules (for example, short interfering nucleic acid (siNA), short interfering RNA (siRNA), double-stranded RNA (dsRNA), micro-RNA (miRNA) or short hairpin RNA (shRNA)) that modulate a gene encoding hsp47, for example, the gene encoding human hsp47. The composition and methods disclosed herein may also be used in treating conditions and disorders associated with hsp47 such as liver fibrosis, pulmonary fibrosis, peritoneal fibrosis and kidney fibrosis.Type: ApplicationFiled: December 8, 2010Publication date: July 21, 2011Inventors: Xiaomei Jin, Lei Yu, Hirokazu Takahashi, Yasunobu Tanaka, Yoshiro Niitsu, Elena Feinstein, Sharon Avkin-Nachum, Hagar Kalinski, Igor Mett, Shai Erlich, Elizabeth C. Squiers
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Patent number: 7163925Abstract: A variety of genetic constructs are disclosed that will find both in vitro and in vivo use in the area of tumor biology and cancer therapy. In particular, expression constructs are provided that contain a p16 encoding region and other regulatory elements necessary for the expression of a p16 transcript. One version of the expression construct is a replication-deficient adenoviral vector. Also provided are methods for the transformation of cell lines and the inhibition of cancer cell proliferation.Type: GrantFiled: May 19, 1998Date of Patent: January 16, 2007Assignee: Board of Regents, The University of Texas SystemInventors: Xiaomei Jin, Jack A. Roth
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Patent number: 6251871Abstract: A variety of genetic constructs are disclosed that will find both in vitro and in vivo use in the area of tumor biology and cancer therapy. In particular, expression constructs are provided that contain a p16 encoding region and other regulatory elements necessary for the expression of a p16 transcript. One version of the expression construct is a replication-deficient adenoviral vector. Also provided are methods for the transformation of cell lines and the inhibition of cancer cell proliferation.Type: GrantFiled: August 13, 1997Date of Patent: June 26, 2001Assignee: Board of Regents, The University of Texas SystemInventors: Xiaomei Jin, Jack A. Roth
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Patent number: 5691198Abstract: A variety of genetic constructs are disclosed that will find both in vitro and in vivo use in the area of tumor biology and cancer therapy. In particular, expression constructs are provided that contain a p16 encoding region and other regulatory elements necessary for the expression of a p16 transcript. One version of the expression construct is a replication-deficient adenoviral vector. Also provided are methods for the transformation of cell lines and the inhibition of cancer cell proliferation.Type: GrantFiled: July 17, 1995Date of Patent: November 25, 1997Assignee: Board of Regents, The University of Texas SystemInventors: Xiaomei Jin, Jack A. Roth