Abstract: Gait, the walking pattern of individuals, is one of the important biometrics modalities. Most of the existing gait recognition methods take silhouettes or articulated body models as gait features. These methods suffer from degraded recognition performance when handling confounding variables, such as clothing, carrying and viewing angle. To remedy this issue, this disclosure proposes to explicitly disentangle appearance, canonical and pose features from RGB imagery. A long short-term memory integrates pose features over time as a dynamic gait feature while canonical features are averaged as a static gait feature. Both of them are utilized as classification features.

Abstract: The present invention belongs to the field of pharmaceutical manufacturing technology. The present invention provides a pharmaceutical composition of a conjugate and a preparation method thereof. The pharmaceutical composition is preferably administered by injection. The docetaxel conjugate has a structural formula as shown in the following formula: (I).

Abstract: The present disclosure provides compounds and pharmaceutically acceptable salts thereof, and methods of using the same. The compounds and methods have a range of utilities as therapeutics, diagnostics, and research tools. In particular, the subject compositions and methods are useful for reducing signaling output of oncogenic proteins.

Abstract: A low-heat-loss operation method of a line-focusing heat collection system and the line-focusing heat collection system are provided. The method includes the following steps. Solar energy is utilized to preheat a collector tube in an empty tube state, so that the collector tube is in a preheating mode. After a set preheating temperature is reached, a heat transfer working medium is injected into the collector tube. In the injection process of the heat transfer working medium, an injection section of the collector tube is converted into a focusing mode from a preheating mode. After heat collection is finished, the circulation of the heat transfer working medium is stopped, and the focusing mode of the collector tube is kept. In the drainage process of the heat transfer working medium, an emptying section of the collector tube is converted into a light heat-tracing mode from a focusing mode.

Abstract: The present invention discloses a same-cavity integrated vertical high-speed multistage superfine pulverizing device and method for walnut shells. The same-cavity integrated vertical high-speed multistage superfine pulverizing device for walnut shells includes a double-channel sliding type feeding device and a same-cavity integrated vertical pulverizing device. The same-cavity integrated vertical pulverizing device includes a material lifting disc and a same-cavity integrated vertical pulverizing barrel. A first-stage coarse crushing region, a second-stage fine crushing region, a third-stage pneumatic impact micro pulverizing region and a fourth-stage airflow mill superfine pulverizing region are disposed in the same-cavity integrated vertical pulverizing barrel.

Abstract: Embodiments of the present disclosure provide an etching method with a metal hard mask. The method is performed on a wafer surface and includes sequentially forming a metal hard mask layer and at least one functional film layer on a wafer surface in a direction away from the wafer surface. The method includes performing a plurality of etching processes on the at least one functional layer and the metal hard mask layer sequentially in a direction close to the wafer surface. An etching gas adopted by at least one etching process includes a hydrogen element and a fluorine element. A ratio of a content of the hydrogen element in the etching gas to a content of the fluorine element in the etching gas is smaller than a predetermined threshold to reduce generation of a byproduct of hydrogen fluorine.

Abstract: The present disclosure provides compounds and pharmaceutically acceptable salts thereof, and methods of using the same. The compounds and methods have a range of utilities as therapeutics, diagnostics, and research tools. In particular, the subject compositions and methods are useful for reducing signaling output of oncogenic proteins.

Abstract: The present disclosure provides a multi-factor quantitative analysis method for deformation of a neighborhood tunnel. The method includes the following steps: analyzing monitoring data generated at a tunnel site; simulating collapse occurring at a shallow buried section of a tunnel; determining the degree of influence of each factor on the tunnel and a stratum; and determining quantitative influence of each factor on tunnel deformation. The present disclosure can not only provide an accurate theoretical basis for the construction of the shallow buried section of the small-distance tunnel, but also guarantee safety and cost saving during tunnel construction.

Abstract: An automobile hub fixture includes a fixture body and a positioning apparatus. The fixture body includes a fixed platform and a plurality of clamping claws arranged at intervals in a circumferential direction of the fixed platform. The clamping claws are configured to clamp an outer rim of a hub. The plurality of clamping claws are connected to a driving member by using a linkage, and the driving member drives the clamping claws to radially move along the fixed platform. The positioning apparatus includes a movable platform slidably connected to the clamping claws. A positioning module configured to position an inner rim or the outer rim of the hub is mounted to the movable platform. The machining device includes a fixture, a machine tool, and a minimal quantity lubrication apparatus. The production line includes a machining device, a loading system, a loading and unloading manipulator, and a catching table.

Abstract: Various embodiments disclose a method for operating a printer apparatus that includes a print head. The method includes causing a media hub to retract a media in a retract direction along a media path. Further, the method includes causing a first media sensor to generate a first signal during retraction of the media. Furthermore, the method includes monitoring the first signal to detect at least one of a leading edge or a trailing edge of a label of the plurality of labels. Upon detecting the at least one of the leading edge or the trailing edge of the label, causing the media hub to retract the media by at least a predetermined distance, wherein the predetermined distance is a distance between the print head and the first media sensor.

Abstract: A three-stage tubular T-shaped degassing device with microbubble axial flow and spiral flow fields is provided, which is applied to quick degassing of a gas-liquid two-phase flow. The three-stage tubular T-shaped degassing device adopts a quick degassing technology combining a microbubble uniform mixed rotational axial flow field and a spiral runner conical spiral flow field with layered jet collision reversing depth degassing. A microbubble uniform mixer is configured to adjust gas-liquid two-phase flow containing big bubbles into microbubble uniform mixed axial flow. A microbubble cyclone is configured to adjust the microbubble uniform mixed axial flow into multiple strands of rotational axial flows containing microbubbles. A rotational axial flow degasser implements the horizontal type microbubble uniform mixed multiple strands rotational axial flow degassing operation to remove most microbubbles to form axial flow gas and axial flow liquid.

Abstract: The three-stage axial flow degassing device adopts an efficient degassing technology including a vertical high speed swirling field, a horizontal rapid axial flow field and a vertical reversing scrubbing field formed by a combination of vertical tubes; the first-stage degasser performs the first-stage segmental vertical high speed swirling degassing operation, removes the gas phase carried by the gas-containing fluid, and forms a primary gas and a primary fluid; the microporous uniform mixer breaks bubbles of the primary fluid and forms a gas-liquid uniform mixed flow; the second-stage degasser performs the second-stage horizontal vane wheel swirling generating rapid axial flow degassing operation, removes the gas phase carried by the gas-liquid uniform mixed flow, and forms a secondary gas and a secondary fluid; the third-stage degasser performs the third-stage vertical reversing deep degassing operation, removes liquid phase carried by the secondary gas, and forms a tertiary gas and a tertiary fluid.

Abstract: It relates to a pharmaceutical combination comprising a KRAS G12C inhibitor, in particular 1-{6-[(4M)-4-(5-Chloro-6-methyl-1H-indazol-4-yl)-5-methyl-3-(1-methyl-1H-indazol-5-yl)-1H-pyrazol-1-yl]-2-azaspiro [3.3] heptan-2-yl} prop-2-en-1-one (Compound A) and one or more therapeutically active agents selected from a SHP2 inhibitor (e.g. TNO155) and a PD-1 inhibitor, pharmaceutical compositions comprising the same; and methods of using such combinations and compositions in the treatment or prevention of a cancer or a tumor, in particular wherein the cancer or tumor is KRAS G12C mutated.

Abstract: A hybrid driving system and a hybrid electric vehicle. The hybrid driving system includes an engine, an input element (20), an output element (23), a box body (24), a first motor (13), a second motor (14), a first planet row, a second planet row, a third planet row, a first clutch (15) and a first brake (16). According to the hybrid driving system of the present disclosure, a basic three-planet-row planet gear configuration is provided through the planet row mechanical structure and the reasonable layout of multiple operating elements (the clutches and the brakes), which can realize at least two E-CVT working modes to obtain higher transmission efficiency.

Abstract: The present application discloses a current collector, and manufacturing method and equipment thereof, and a current collector preform, wherein the current collector may include a porous foam metal part and solid metal part(s); the porous foam metal part may be uncompressed, and the porous foam metal part may include a first edge and a second edge oppositely distributed in a first direction, the first direction may be perpendicular to the thickness direction of the current collector; the first edge and/or the second edge may be connected with the solid metal part(s).

Abstract: A semiconductor device includes a first stack of alternating first word line layers and first insulating layers over a semiconductor layer. A first channel structure extends from the semiconductor layer and through a first array region of the first stack. A second stack of alternating second word line layers and second insulating layers are over the first stack. A second channel structure extends from the first channel structure and through a second array region of the second stack. A thickness of a particular first insulating layer, which is positioned closest to the second stack relative to other first insulating layers, is a sum of at least two times an average thickness of the other first insulating layers and at least one time an average thickness of the first word line layers in the first array region.

Abstract: A semiconductor device includes a first stack of alternating first word line layers and first insulating layers over a semiconductor layer. The first stack includes a first array region and a first staircase region adjacent to the first array region. The semiconductor device includes a second stack of alternating second word line layers and second insulating layers, where the second stack includes a second array region over the first array region and a second staircase region adjacent to the second array region and over the first staircase region. The first stack further includes a first transition layer over the first word line layers. The first transition layer includes a first dielectric portion in the first array region that surrounds the first channel structure and a first conductive portion. The first transition layer is disposed between two adjacent first insulating layers of the first insulating layers.

Abstract: The embodiments described herein involve electrochemical cells that have a heating element integrated into the electrochemical cell. In some aspects, an electrochemical cell comprises an anode current collector, an anode material disposed on the anode current collector, a cathode current collector, a cathode material disposed on a first side of the cathode current collector, a separator disposed between the anode material and the cathode material, and a heating element disposed on a second side of the cathode current collector, the second side opposite the first side. The heating element may include an electrically conductive material and a conductive material and disposed in an insulative material.

Abstract: Systems and methods for personalized dose and fractionation for radiation therapy are described herein. An example method can include predicting a patient-specific radiosensitivity parameter alpha (?) value for a tumor, where the patient-specific radiosensitivity parameter alpha (?) value is predicted based on a first set of signature genes. The method can also include predicting a patient-specific radiosensitivity parameter beta (?) value for the tumor, where the patient-specific radiosensitivity parameter beta (?) value is predicted based on a second set of signature genes. The method can further include calculating a patient-specific dose and fractionation using a radiation cytotoxicity score (RCS) function and the patient-specific radiosensitivity parameters alpha (?) and beta (?) values. RCS is predictive of clinical outcome.