Abstract: The present disclosure provides Low Temperature NOx-Absorber (LT-NA) catalyst compositions, catalyst articles, and an emission treatment system for treating an exhaust gas, each including the LT-NA catalyst compositions. Further provided are methods for reducing a NOx level in an exhaust gas stream using the LT-NA catalyst articles. In particular, the LT-NA catalyst compositions include a first zeolite, a first palladium component, and a plurality of platinum nanoparticles. The LT-NA catalyst compositions exhibit enhanced regeneration efficiency with respect to NOx adsorption capacity, even after hydrothermal aging.

Abstract: The present disclosure provides a robot, a control method for robot and a storage medium, the robot includes a memory, a processor and a computer program stored on the memory and running on the processor, and when the processor executes the computer program to obtain, material information of a working surface and determine, a target running speed of the robot according to the material information, and control the robot to run at the target running speed. The robot provided by the present disclosure controls the operating speed according to the material information of the working surface, and the robot can clean at different speeds for different materials when cleaning. If the detected material of the working surface is a material that is not easy to clean, you can set the speed to a low speed mode accordingly.

Abstract: In an aspect, the disclosure provides for compounds (II), compositions, and methods of administering the compounds and compositions to a patient in need thereof. In another aspect, the disclosure relates to compounds and compositions for treating cancer, for example, lymphoid leukemia. The disclosure further provides for compounds which inhibit two phosphoinositide 3-kinase (PI3K) isoforms, y and ?, pharmaceutical compositions comprising said compounds, and methods of using said compounds and pharmaceutical compositions for treatment, amelioration, and/or prevention of non-Hodgkin lymphoma.

Abstract: The present invention discloses a fully-assembled staircase system and an assembly method. The fully-assembled staircase system includes a stair slab, stair steps, stair stringers, landing slabs, steel connectors, and a stair handrail, where a main body of the stair slab is an inclined flat plate structure, lap joints are disposed at an upper end and a lower end of the stair slab LTB, an outer edge of an upper surface of the lap joint is provided with first grooves, one side of the landing slab PB is provided with second grooves, the stair stringer is an inverted T-shaped structure, a top surface of a web of the stair stringer is provided with third grooves, two flanges of the stair stringer are respectively fixedly lapped with the stair slab and the landing slab, the first groove, the third groove, and the second groove after the lapping jointly form a steel-connector groove.

Abstract: The present disclosure is directed to a Low Temperature NOx-Absorber (LT-NA) catalyst composition which exhibits NOx adsorption in a broad temperature and space velocity range, and shifts NOx desorption to a desired temperature range. In particular, the LT-NA composition includes a large pore zeolite containing a palladium component and a small or medium pore zeolite containing a palladium component. Further provided is a catalyst article including the LT-NA catalyst composition, an emission treatment system for treating an exhaust gas including the catalyst article, and methods for reducing a NOx level in an exhaust gas stream using the catalyst article.

Abstract: The present disclosure provides conjugate compositions comprising non-hydrolyzable, non-cleavable, stable linkers, a targeting moiety, and a therapeutic or chemotherapeutic agent. More specifically the present disclosure provides for compositions comprising non-hydrolyzable, non-cleavable, stable linkers, a somatostatin receptor (SSTR) targeting moiety, such as lanreotide, and a chemotherapeutic agent targeting microtubules, such as mertansine. Methods of using the compositions to treat cancer and other diseases are also provided.

Abstract: A substituted dihydropyrazole compound as shown in formula I, which compound has a selective inhibitory effect on RIPK1, and a pharmaceutically acceptable salt, a stereoisomer, a solvate or a prodrug thereof, wherein the definition of each group in the formula is detailed in the description. In addition is a pharmaceutical composition containing the compound, and the use thereof in the preparation of a drug for treating RIPK1-related diseases or conditions.

Abstract: The present disclosure is directed to Low Temperature NOx-Absorber (LT-NA) catalyst compositions, catalyst articles, and an emission treatment system for treating an exhaust gas, each including the LT-NA catalyst compositions. Further provided are methods for reducing a NOx level in an exhaust gas stream using the catalyst article. In particular, the LT-NA compositions include a zeolite containing a first metal component including palladium and a second metal component which is an alkaline earth metal component, an oxide of an alkaline earth metal component, a rare earth metal component, an oxide of a rare earth metal component, or a combination thereof. The LT-NA compositions exhibit increased low temperature NOx adsorption capacity and enhanced hydrothermal stability.

Abstract: Various embodiments relate to a compound (represented by Formula I) or a pharmaceutically acceptable salt or tautomer thereof. The compound may selectively inhibit a Forkhead Box O1 (FOXO1) transcription factor. Various embodiments relate to methods comprising administering to a mammal having a disease or disorder associated with impaired pancreatic endocrine function, a therapeutically effective amount of the compound or a pharmaceutically acceptable salt or tautomer thereof. Various embodiments relate to methods for producing enteroendocrine cells that make and secrete insulin in a mammal, comprising administering to the mammal an effective amount of the compound or a pharmaceutically acceptable salt or tautomer thereof.

Abstract: A substituted heterocyclic amide compound having a selective inhibitory effect on RIPK1, and a pharmaceutically acceptable salt, a stereoisomer, a solvate or a prodrug thereof, and a pharmaceutical composition containing the compound, and the use of same in the preparation of a drug for treating a RIPK1-related diseases or conditions.

Abstract: An appliance, a method and system for controlling the same, a server, an appliance controlling apparatus are provided. The method for controlling an appliance includes: receiving a parameter acquiring request transmitted by the appliance or an appliance controlling apparatus, the parameter acquiring request including an identifier of the appliance; acquiring a recommended parameter configuration list corresponding to the identifier of the appliance according to the parameter acquiring request; and transmitting the recommended parameter configuration list to the appliance or the appliance controlling apparatus enables the appliance to run according to the recommended parameter configuration list or enable the appliance controlling apparatus to control running of the appliance according to the recommended parameter configuration list.

Abstract: This invention presents a solar light collecting and guiding system for stabilizing the output light intensity, wherein the system comprising an array of converging lenses and optical fibers for collecting light focused by converging lenses. The fibers and the lenses are in one-to-one correspondence wherein the input end of an optical fiber is located in the focus position of the corresponding converging lens, and the axis of the optical fiber overlaps with the principal axis of the corresponding converging lens. The system is equipped with a sunlight tracking positioning device for synchronized motion, wherein the device is applied to tracking the sun light ray vertical incident into the central converging lens. The system has the function of outputting stable light intensity, that is, it can effectively reduce the variation of the collecting efficiency caused by the positioning deviation between the incident angle of sunlight and the designed input angle.

Abstract: This invention presents a solar light collecting and guiding system for stabilizing the output light intensity, wherein the system comprising an array of converging lenses and optical fibers for collecting light focused by converging lenses. The fibers and the lenses are in one-to-one correspondence wherein the input end of an optical fiber is located in the focus position of the corresponding converging lens, and the axis of the optical fiber overlaps with the principal axis of the corresponding converging lens. The system is equipped with a sunlight tracking positioning device for synchronized motion, wherein the device is applied to tracking the sun light ray vertical incident into the central converging lens. The system has the function of outputting stable light intensity, that is, it can effectively reduce the variation of the collecting efficiency caused by the positioning deviation between the incident angle of sunlight and the designed input angle.

Abstract: A solar tracking sensor includes lens and four fibers respectively representing four directions installed in a lens barrel to serve as a fine-positioning daylighting module, and four groups of fibers installed on the side of the lens barrel to serve as a coarse-positioning daylighting module. A circuit board and four photocells are installed at the bottom of a cassette. Each photocell is connected to fine positioning fibers located in the same direction as the photocell, and is connected to coarse positioning fibers located in a direction diagonal to the direction of the photocell. By using a daylighting method of combining fine-positioning daylighting and coarse-positioning daylighting, the number of the photocells is reduced, the design of the circuit board is simplified, and costs are reduced; moreover, because the coarse-positioning daylighting module can collect sunlight in a wide-angle range, the tracking angle range of the sensor is enlarged.

Abstract: A dorsal aortic injection method of chicken embryos for improving transgenic efficiency, comprising the following steps: injecting adeno-associated virus particles into the dorsal aorta of each 2.5-day-old chicken embryo outside eggshell, individually transferring the injected chicken embryos into their recipient eggshells (coming from double yolk eggs), and proceeding to hatch. The disclosure realizes the outside-eggshell injection of the chicken embryo dorsal aorta through the modified dorsal aortic injection method, improves the accuracy of injection, and also realizes the direct observation of the development process of the chicken embryos.

Abstract: The present disclosure is directed to a Low Temperature NOx-Absorber (LT-NA) catalyst composition which exhibits NOx adsorption in a broad temperature and space velocity range, and shifts NOx desorption to a desired temperature range. In particular, the LT-NA composition includes a large pore zeolite containing a palladium component and a small or medium pore zeolite containing a palladium component. Further provided is a catalyst article including the LT-NA catalyst composition, an emission treatment system for treating an exhaust gas including the catalyst article, and methods for reducing a NOx level in an exhaust gas stream using the catalyst article.

Abstract: The present invention relates to diesel oxidation catalyst compositions and catalyst articles, wherein the compositions and articles include a plurality of platinum group nanoparticles substantially in fully reduced form, wherein the nanoparticles have an average particle size of about 1 to about 10 nm and at least about 90% of the nanoparticles have a particle size of +/? about 2 nm of the average particle size. Such compositions can further include a refractory metal oxide material, wherein the nanoparticles and refractory metal oxide material can be combined within the same coating on a substrate or can be applied sequentially on a substrate. The nanoparticles can advantageously be substantially free of halides, alkali metals, alkaline earth metals, sulfur compounds, and boron compounds. Methods of preparing and using such compositions and catalyst articles (e.g., for the treatment of diesel exhaust gas streams) are also provided herein.

Abstract: The invention relates to new compounds that reduce c-Myc expression and useful for cancer treatment, particularly hematological cancers such as aggressive B- and T-cell lymphomas. The new compounds may be combined with adjunct c-Myc inhibor agents such as a PI3K inhibitor, CK-1 inhibitor, Akt-inhibitor, proteasome inhibitor and/or mTor inhibitor. The c-Myc reducing agent may be provided as a lead-in treatment to reduce or initiate reduction of c-Myc prior to administration of the adjunct cancer therapeutic agent. Treatment with a c-Myc reducing agent modulates the disease state of the c-Myc overexpressing cancer making it less malignant and more susceptible to adjunctive cancer therapies.

Abstract: This invention relates to antimicrobial gallium compounds, and to monomers containing gallium complex moieties that can be used in oral care products and dental materials, and which can reduce or eliminate dental caries and bacterial or fungal infections associated with medical and dental devices.

Abstract: An onsite steel rail laser processing engineering vehicle, including a laser processing power engineering vehicle and a laser processing cart, the laser processing power engineering vehicle is connected to the laser processing cart; the onsite steel rail laser processing engineering vehicle further comprises a transport mechanism disposed on the laser processing power engineering vehicle; through movement and rotation, the transport mechanism transports the laser processing cart into the laser processing power engineering vehicle or transports the laser processing cart out from the laser processing power engineering vehicle and places it on rails.