Patents by Inventor Xiaonan GAO

Xiaonan GAO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250092387
    Abstract: A method and an apparatus for optimizing an mRNA sequence, an mRNA molecule, a pharmaceutical composition, and a use thereof are provided. The disclosure relates to the technical field of artificial intelligence, specifically to technical fields such as biological computing. The method for optimizing the mRNA sequence include: obtaining a first mRNA sequence for synthesizing a protein of interest, where the first mRNA sequence includes a 5? untranslated region sequence and a coding region sequence; and adjusting the 5? untranslated region sequence and the coding region sequence with the goal of maximizing a first score of the first mRNA sequence, so as to obtain an optimized second mRNA sequence for synthesizing the protein of interest, where the first score reflects at least one of the following indicators of the first mRNA sequence: translation initiation efficiency, codon adaptation index, and minimum free energy.
    Type: Application
    Filed: December 4, 2024
    Publication date: March 20, 2025
    Applicant: BEIJING BAIDU NETCOM SCIENCE TECHNOLOGY CO., LTD.
    Inventors: Yang LIU, Xiaomin FANG, Jie GAO, Xiaonan ZHANG, Jingzhou HE
  • Publication number: 20250095783
    Abstract: A method for obtaining an antibody sequence includes: obtaining first features of amino acids at different sequence positions according to an antigen multiple sequence alignment (MSA) sequence, an antibody MSA sequence, and a concatenated sequence of the antigen MSA sequence and the antibody MSA sequence; obtaining second feature of the amino acids at different 3D coordinates according to a graph constructed according to a reference antigen-antibody complex; fusing the first features of amino acids at different sequence positions with the second features of amino acids at 3D coordinates corresponding to the different sequence positions, and obtaining probability information of each of the amino acids at different positions in the antibody sequence according to fused features; and obtaining a target antibody sequence according to the amino acids and their probability information at different positions in the antibody sequence.
    Type: Application
    Filed: December 3, 2024
    Publication date: March 20, 2025
    Applicant: BEIJING BAIDU NETCOM SCIENCE TECHNOLOGY CO., LTD.
    Inventors: Jie GAO, Jing HU, Xiaomin FANG, Xiaonan ZHANG
  • Patent number: 12233482
    Abstract: An intelligent electromagnetic induction heating leveling system, comprising: a trolley type leveler, an unmanned aerial vehicle temperature measurement device, indoor positioning devices used for converting position information of a trolley of the trolley type leveler and the unmanned aerial vehicle temperature measurement device into position parameters, and a control system. The system can perform, according to preset data parameters, data transmission by means of a wireless local area network and the unmanned aerial vehicle temperature measurement device and control the unmanned aerial vehicle temperature measurement device to move to a specified position. The system intelligently controls the leveling temperature and leveling time of a leveling area, and thus may be suitable for leveling of weld joints having different sizes and depths, and achieve a good leveling effect. Also provided is an intelligent electromagnetic induction heating leveling method.
    Type: Grant
    Filed: November 24, 2022
    Date of Patent: February 25, 2025
    Assignee: JIANGSU UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventors: Jing Xu, Xiaonan Chang, Jiayang Gu, Yefan Wang, Bingwu Gao, Shengrong Li, Zixi He, Qiuyan Wang, Changwen Yang, Xinyang Sun
  • Publication number: 20250054572
    Abstract: A method for protein docking includes docking a first protein and a second protein according to at least two molecular docking methods to generate a complex conformation in each round of iteration; recognizing that an iteration end condition is not satisfied, continuing a next round of iteration until the iteration end condition is satisfied, and obtaining a final complex conformation.
    Type: Application
    Filed: October 29, 2024
    Publication date: February 13, 2025
    Applicant: BEIJING BAIDU NETCOM SCIENCE TECHNOLOGY CO., LTD.
    Inventors: Jie Gao, Jing Hu, Xiaomin Fang, Xiaonan Zhang
  • Patent number: 11081888
    Abstract: The present disclosure provides a method, an apparatus, and a medium for calculating capacities of a plurality of photovoltaic power stations. The method includes: receiving a plurality of historical weather data sets from the plurality of weather monitoring stations; determining a scene year based on the plurality of historical weather data sets; receiving an actual generating capacity of each photovoltaic power station predicted by a power system dispatch center; extracting weather data of each photovoltaic power station in the scene year from the corresponding historical weather data set; obtaining an available generating capacity of each photovoltaic power station in the scene year based on the weather data; and determining a capacity of each photovoltaic power station in the scene year according to the actual generating capacity and the available generating capacity of each photovoltaic power station.
    Type: Grant
    Filed: August 13, 2019
    Date of Patent: August 3, 2021
    Assignees: TSINGHUA UNIVERSITY, ECONOMIC AND TECHNOLOGICAL RESEARCH INSTITUTE, STATE GRID SHANDONG ELECTRIC POWER COMPANY
    Inventors: Jian Zhang, Xin Tian, Xueliang Li, Ning Zhang, Jian Wu, Long Zhao, Yan Wang, Zhijie Zheng, Hong Mou, Yuan Wang, Xiaoming Liu, Jie Zhang, Xiaonan Gao, Jianing Zhang, Dong Liu, Ying Mou, Shanjie Jia, Bo Li, Yi Zhu, Xiaohai Gao, Xin Wei, Jia Wei
  • Publication number: 20200059101
    Abstract: The present disclosure provides a method, an apparatus, and a medium for calculating capacities of a plurality of photovoltaic power stations. The method includes: receiving a plurality of historical weather data sets from the plurality of weather monitoring stations; determining a scene year based on the plurality of historical weather data sets; receiving an actual generating capacity of each photovoltaic power station predicted by a power system dispatch center; extracting weather data of each photovoltaic power station in the scene year from the corresponding historical weather data set; obtaining an available generating capacity of each photovoltaic power station in the scene year based on the weather data; and determining a capacity of each photovoltaic power station in the scene year according to the actual generating capacity and the available generating capacity of each photovoltaic power station.
    Type: Application
    Filed: August 13, 2019
    Publication date: February 20, 2020
    Inventors: Jian ZHANG, Xin TIAN, Xueliang LI, Ning ZHANG, Jian WU, Long ZHAO, Yan WANG, Zhijie ZHENG, Hong MOU, Yuan WANG, Xiaoming LIU, Jie ZHANG, Xiaonan GAO, Jianing ZHANG, Dong LIU, Ying MOU, Shanjie JIA, Bo LI, Yi ZHU, Xiaohai GAO, Xin WEI, Jia WEI