Patents by Inventor Xiaonan Ma

Xiaonan Ma has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240078672
    Abstract: Systems and methods for analyzing pathologies utilizing quantitative imaging are presented herein. Advantageously, the systems and methods of the present disclosure utilize a hierarchical analytics framework that identifies and quantify biological properties/analytes from imaging data and then identifies and characterizes one or more pathologies based on the quantified biological properties/analytes. This hierarchical approach of using imaging to examine underlying biology as an intermediary to assessing pathology provides many analytic and processing advantages over systems and methods that are configured to directly determine and characterize pathology from underlying imaging data.
    Type: Application
    Filed: November 8, 2023
    Publication date: March 7, 2024
    Applicant: ELUCID BIOIMAGING INC.
    Inventors: Andrew J. BUCKLER, Kjell JOHNSON, Xiaonan MA, Keith A. MOULTON, David S. PAIK
  • Publication number: 20240078671
    Abstract: Systems and methods for analyzing pathologies utilizing quantitative imaging are presented herein. Advantageously, the systems and methods of the present disclosure utilize a hierarchical analytics framework that identifies and quantify biological properties/analytes from imaging data and then identifies and characterizes one or more pathologies based on the quantified biological properties/analytes. This hierarchical approach of using imaging to examine underlying biology as an intermediary to assessing pathology provides many analytic and processing advantages over systems and methods that are configured to directly determine and characterize pathology from underlying imaging data.
    Type: Application
    Filed: November 8, 2023
    Publication date: March 7, 2024
    Applicant: ELUCID BIOIMAGING INC.
    Inventors: Andrew J. BUCKLER, Kjell JOHNSON, Xiaonan MA, Keith A. MOULTON, David S. PAIK
  • Publication number: 20240078673
    Abstract: Systems and methods for analyzing pathologies utilizing quantitative imaging are presented herein. Advantageously, the systems and methods of the present disclosure utilize a hierarchical analytics framework that identifies and quantify biological properties/analytes from imaging data and then identifies and characterizes one or more pathologies based on the quantified biological properties/analytes. This hierarchical approach of using imaging to examine underlying biology as an intermediary to assessing pathology provides many analytic and processing advantages over systems and methods that are configured to directly determine and characterize pathology from underlying imaging data.
    Type: Application
    Filed: November 8, 2023
    Publication date: March 7, 2024
    Applicant: ELUCID BIOIMAGING INC.
    Inventors: Andrew J. BUCKLER, Kjell JOHNSON, Xiaonan MA, Keith A. MOULTON, David S. PAIK
  • Publication number: 20230326166
    Abstract: Systems and methods for analyzing pathologies utilizing quantitative imaging are presented herein. Advantageously, the systems and methods of the present disclosure utilize a hierarchical analytics framework that identifies and quantify biological properties/analytes from imaging data and then identifies and characterizes one or more pathologies based on the quantified biological properties/analytes. This hierarchical approach of using imaging to examine underlying biology as an intermediary to assessing pathology provides many analytic and processing advantages over systems and methods that are configured to directly determine and characterize pathology from underlying imaging data.
    Type: Application
    Filed: April 26, 2023
    Publication date: October 12, 2023
    Applicant: ELUCID BIOIMAGING INC.
    Inventors: Andrew J. BUCKLER, Kjell JOHNSON, Xiaonan MA, Keith A. MOULTON, David S. PAIK
  • Publication number: 20230237759
    Abstract: Systems and methods for analyzing pathologies utilizing quantitative imaging are presented herein. Advantageously, the systems and methods of the present disclosure utilize a hierarchical analytics framework that identifies and quantify biological properties/analytes from imaging data and then identifies and characterizes one or more pathologies based on the quantified biological properties/analytes. This hierarchical approach of using imaging to examine underlying biology as an intermediary to assessing pathology provides many analytic and processing advantages over systems and methods that are configured to directly determine and characterize pathology from underlying imaging data.
    Type: Application
    Filed: February 8, 2023
    Publication date: July 27, 2023
    Applicant: ELUCID BIOIMAGING INC.
    Inventors: Andrew J. BUCKLER, Kjell JOHNSON, Xiaonan MA, Keith A. MOULTON, Mark A. BUCKLER, Vladimir VALTCHINOV, David S. PAIK
  • Patent number: 11676359
    Abstract: Systems and methods for analyzing pathologies utilizing quantitative imaging are presented herein. Advantageously, the systems and methods of the present disclosure utilize a hierarchical analytics framework that identifies and quantify biological properties/analytes from imaging data and then identifies and characterizes one or more pathologies based on the quantified biological properties/analytes. This hierarchical approach of using imaging to examine underlying biology as an intermediary to assessing pathology provides many analytic and processing advantages over systems and methods that are configured to directly determine and characterize pathology from underlying imaging data.
    Type: Grant
    Filed: May 24, 2021
    Date of Patent: June 13, 2023
    Assignee: ELUCID BIOIMAGING INC.
    Inventors: Andrew J. Buckler, Kjell Johnson, Xiaonan Ma, Keith A. Moulton, Mark A. Buckler, Vladimir Valtchinov, David S. Paik
  • Publication number: 20230086427
    Abstract: This application relates to a client-server architecture that enables file sharing between an instructor and a class. The files are stored in a storage service accessible via a network, and a separate copy of each file can be shared with each student in the class. In order to facilitate the sharing of multiple copies of the file, a share pool is created in a partition of the storage service allocated to the instructor. The share pool includes a number of stub files that are placeholders for clones of the shared file. A share handler service receives a request to share a file with a class, requests a number of stub files from the share pool, and utilizes the number of stub files to generate clones of the shared file in the partition of the storage service. Students are then granted access to the clones in the partition.
    Type: Application
    Filed: September 29, 2022
    Publication date: March 23, 2023
    Inventors: James F. LOCKWOOD, Van HONG, Xiaonan MA, Sugam JAIN, Pavel V. DUDRENOV, Ori HERRNSTADT
  • Patent number: 11607179
    Abstract: Systems and methods for analyzing pathologies utilizing quantitative imaging are presented herein. Advantageously, the systems and methods of the present disclosure utilize a hierarchical analytics framework that identifies and quantify biological properties/analytes from imaging data and then identifies and characterizes one or more pathologies based on the quantified biological properties/analytes. This hierarchical approach of using imaging to examine underlying biology as an intermediary to assessing pathology provides many analytic and processing advantages over systems and methods that are configured to directly determine and characterize pathology from underlying imaging data.
    Type: Grant
    Filed: May 24, 2021
    Date of Patent: March 21, 2023
    Assignee: ELUCID BIOIMAGING INC.
    Inventors: Andrew J. Buckler, Kjell Johnson, Xiaonan Ma, Keith A. Moulton, Mark A. Buckler, Vladimir Valtchinov, David S. Paik
  • Patent number: 11461279
    Abstract: This application relates to a client-server architecture that enables file sharing between an instructor and a class. The files are stored in a storage service accessible via a network, and a separate copy of each file can be shared with each student in the class. In order to facilitate the sharing of multiple copies of the file, a share pool is created in a partition of the storage service allocated to the instructor. The share pool includes a number of stub files that are placeholders for clones of the shared file. A share handler service receives a request to share a file with a class, requests a number of stub files from the share pool, and utilizes the number of stub files to generate clones of the shared file in the partition of the storage service. Students are then granted access to the clones in the partition.
    Type: Grant
    Filed: September 28, 2018
    Date of Patent: October 4, 2022
    Assignee: Apple Inc.
    Inventors: James F. Lockwood, Van Hong, Xiaonan Ma, Sugam Jain, Pavel V. Dudrenov, Ori Herrnstadt
  • Patent number: 11257584
    Abstract: Advanced reporting systems based on ontology development for quantitative imaging biomarkers, information modeling to integrate heterogeneous data types relevant to quantitative medical analysis, and a knowledge representation framework for their statistical validation.
    Type: Grant
    Filed: August 13, 2018
    Date of Patent: February 22, 2022
    Assignee: ELUCID BIOIMAGING INC.
    Inventors: Mary E. Buckler, Xiaonan Ma, Lawrence Martell, Andrew J. Buckler
  • Publication number: 20210390689
    Abstract: Systems and methods for analyzing pathologies utilizing quantitative imaging are presented herein. Advantageously, the systems and methods of the present disclosure utilize a hierarchical analytics framework that identifies and quantify biological properties/analytes from imaging data and then identifies and characterizes one or more pathologies based on the quantified biological properties/analytes. This hierarchical approach of using imaging to examine underlying biology as an intermediary to assessing pathology provides many analytic and processing advantages over systems and methods that are configured to directly determine and characterize pathology from underlying imaging data.
    Type: Application
    Filed: May 24, 2021
    Publication date: December 16, 2021
    Applicant: ELUCID BIOIMAGING INC
    Inventors: Andrew J. BUCKLER, Kjell JOHNSON, Xiaonan MA, Keith A. MOULTON, Mark A. BUCKLER, Vladimir VALTCHINOV, David S. PAIK
  • Publication number: 20210282719
    Abstract: Systems and methods for analyzing pathologies utilizing quantitative imaging are presented herein. Advantageously, the systems and methods of the present disclosure utilize a hierarchical analytics framework that identifies and quantify biological properties/analytes from imaging data and then identifies and characterizes one or more pathologies based on the quantified biological properties/analytes. This hierarchical approach of using imaging to examine underlying biology as an intermediary to assessing pathology provides many analytic and processing advantages over systems and methods that are configured to directly determine and characterize pathology from underlying imaging data.
    Type: Application
    Filed: May 24, 2021
    Publication date: September 16, 2021
    Applicant: ELUCID BIOIMAGING INC.
    Inventors: Andrew J. BUCKLER, Kjell JOHNSON, Xiaonan MA, Keith A. MOULTON, Mark A. BUCKLER, Vladimir VALTCHINOV, David S. PAIK
  • Patent number: 11120312
    Abstract: Systems and methods for analyzing pathologies utilizing quantitative imaging are presented herein. Advantageously, the systems and methods of the present disclosure utilize a hierarchical analytics framework that identifies and quantify biological properties/analytes from imaging data and then identifies and characterizes one or more pathologies based on the quantified biological properties/analytes. This hierarchical approach of using imaging to examine underlying biology as an intermediary to assessing pathology provides many analytic and processing advantages over systems and methods that are configured to directly determine and characterize pathology from underlying imaging data.
    Type: Grant
    Filed: November 28, 2018
    Date of Patent: September 14, 2021
    Assignee: ELUCID BIOIMAGING INC.
    Inventors: Andrew J. Buckler, Kjell Johnson, Xiaonan Ma, Keith A. Moulton, Mark A. Buckler, Vladimir Valtchinov, David S. Paik
  • Patent number: 11113812
    Abstract: Systems and methods for analyzing pathologies utilizing quantitative imaging are presented herein. Advantageously, the systems and methods of the present disclosure utilize a hierarchical analytics framework that identifies and quantify biological properties/analytes from imaging data and then identifies and characterizes one or more pathologies based on the quantified biological properties/analytes. This hierarchical approach of using imaging to examine underlying biology as an intermediary to assessing pathology provides many analytic and processing advantages over systems and methods that are configured to directly determine and characterize pathology from underlying imaging data.
    Type: Grant
    Filed: November 28, 2018
    Date of Patent: September 7, 2021
    Assignee: ELUCID BIOIMAGING INC.
    Inventors: Andrew J. Buckler, Kjell Johnson, Xiaonan Ma, Keith A. Moulton, Mark A. Buckler, Vladimir Valtchinov, David S. Paik
  • Patent number: 11094058
    Abstract: Systems and methods for analyzing pathologies utilizing quantitative imaging are presented herein. Advantageously, the systems and methods of the present disclosure utilize a hierarchical analytics framework that identifies and quantify biological properties/analytes from imaging data and then identifies and characterizes one or more pathologies based on the quantified biological properties/analytes. This hierarchical approach of using imaging to examine underlying biology as an intermediary to assessing pathology provides many analytic and processing advantages over systems and methods that are configured to directly determine and characterize pathology from underlying imaging data.
    Type: Grant
    Filed: November 28, 2018
    Date of Patent: August 17, 2021
    Assignee: ELUCID BIOIMAGING INC.
    Inventors: Andrew J. Buckler, Kjell Johnson, Xiaonan Ma, Keith A. Moulton, Mark A. Buckler, Vladimir Valtchinov, David S. Paik
  • Patent number: 11087459
    Abstract: Systems and methods for analyzing pathologies utilizing quantitative imaging are presented herein. Advantageously, the systems and methods of the present disclosure utilize a hierarchical analytics framework that identifies and quantify biological properties/analytes from imaging data and then identifies and characterizes one or more pathologies based on the quantified biological properties/analytes. This hierarchical approach of using imaging to examine underlying biology as an intermediary to assessing pathology provides many analytic and processing advantages over systems and methods that are configured to directly determine and characterize pathology from underlying imaging data.
    Type: Grant
    Filed: November 28, 2018
    Date of Patent: August 10, 2021
    Assignee: ELUCID BIOIMAGING INC.
    Inventors: Andrew J. Buckler, Kjell Johnson, Xiaonan Ma, Keith A. Moulton, Mark A. Buckler, Vladimir Valtchinov, David S. Paik
  • Patent number: 11087460
    Abstract: Systems and methods for analyzing pathologies utilizing quantitative imaging are presented herein. Advantageously, the systems and methods of the present disclosure utilize a hierarchical analytics framework that identifies and quantify biological properties/analytes from imaging data and then identifies and characterizes one or more pathologies based on the quantified biological properties/analytes. This hierarchical approach of using imaging to examine underlying biology as an intermediary to assessing pathology provides many analytic and processing advantages over systems and methods that are configured to directly determine and characterize pathology from underlying imaging data.
    Type: Grant
    Filed: November 30, 2018
    Date of Patent: August 10, 2021
    Assignee: ELUCID BIOIMAGING INC.
    Inventors: Andrew J. Buckler, Kjell Johnson, Xiaonan Ma, Keith A. Moulton, Mark A. Buckler, Vladimir Valtchinov, David S. Paik
  • Patent number: 11071501
    Abstract: Systems and methods for analyzing pathologies utilizing quantitative imaging are presented herein. Advantageously, the systems and methods of the present disclosure utilize a hierarchical analytics framework that identifies and quantify biological properties/analytes from imaging data and then identifies and characterizes one or more pathologies based on the quantified biological properties/analytes. This hierarchical approach of using imaging to examine underlying biology as an intermediary to assessing pathology provides many analytic and processing advantages over systems and methods that are configured to directly determine and characterize pathology from underlying imaging data.
    Type: Grant
    Filed: November 28, 2018
    Date of Patent: July 27, 2021
    Assignee: ELUCID BIOIWAGING INC.
    Inventors: Andrew J. Buckler, Kjell Johnson, Xiaonan Ma, Keith A. Moulton, Mark A. Buckler, Vladimir Valtchinov, David S. Paik
  • Patent number: 10755810
    Abstract: Methods and systems are disclosed for structuring and using information pertinent to in vivo biomarkers, specifically quantitative imaging biomarkers, using semantic web technology for personalized medicine and discovery science. It supports the development and application of statistical evidence at a level of granularity and sophistication more closely tied to the complexity of the disease itself and its underlying biology, including technology linking multiple biological scales, than has previously been eedisclosed. It provides data and computational services to analyze quantitative imaging and non-imaging data, coupled with multi-scale modeling to elucidate pre-symptomatic and clinical disease processes. It may be used to assess technical or analytical performance for its own sake and/or to further annotate the quantitative analysis.
    Type: Grant
    Filed: August 15, 2016
    Date of Patent: August 25, 2020
    Assignee: ELUCID BIOIMAGING INC.
    Inventors: Andrew J. Buckler, Keith A. Moulton, Mary Buckler, Larry Martell, David S. Paik, Xiaonan Ma, Samantha St. Pierre
  • Patent number: 10740880
    Abstract: The present disclosure provides for improved image analysis via novel deblurring and segmentation techniques of image data. These techniques advantageously account for and incorporate segmentation of biological analytes into a deblurring process for an image. Thus, the deblurring of the image may advantageously be optimized for enabling identification and quantitative analysis of one or more biological analytes based on underlying biological models for those analytes. The techniques described herein provide for significant improvements in the image deblurring and segmentation process which reduces signal noise and improves the accuracy of the image. In particular, the system and methods described herein advantageously utilize unique optimization and tissue characteristics image models which are informed by the underlying biology being analyzed, (for example by a biological model for the analytes). This provides for targeted deblurring and segmentation which is optimized for the applied image analytics.
    Type: Grant
    Filed: January 18, 2018
    Date of Patent: August 11, 2020
    Assignee: ELUCID BIOIMAGING INC.
    Inventors: David S. Paik, Andrew J. Buckler, Kjell Johnson, Xiaonan Ma, Keith A. Moulton