Patents by Inventor Xiaoning Jiang

Xiaoning Jiang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12635974
    Abstract: A method for using metastable perfluorocarbon nanodroplets for ultrasonic lysis of blood clots includes administering metastable perfluorocarbon nanodroplets into a blood vessel that includes or that leads to a blood vessel that includes a blood clot, the metastable perfluorocarbon nanodroplets each have a liquid core comprising a perfluorocarbon material that has a boiling point below 25° C. at atmospheric pressure and that remains stable in liquid form at 25° C. at atmospheric pressure. The method further includes applying ultrasound energy to the perfluorocarbon nanodroplets within or surrounding the blood clot, causing the perfluorocarbon nanodroplets to vaporize and convert to bubbles, which cavitate and lyse the blood clot.
    Type: Grant
    Filed: September 9, 2020
    Date of Patent: May 26, 2026
    Assignees: The Regents of the University of Michigan, North Carolina State University, The University of North Carolina at Chapel Hill
    Inventors: Paul Alexander Dayton, Jinwook Kim, Xiaoning Jiang, Zhen Xu
  • Publication number: 20260128018
    Abstract: A display device and a display method are provided. The display device includes: a memory for storing at least one pre-stored image; and a controller for: obtaining first and second target images according to at least one pre-stored image; and controlling a display module, according to a first control instruction, to display the second target image and hide a display of at least one first sub-region in a first region in a frame displayed after switching from the first target image to the second target image. A size of the first target image is different from that of the second target image, and/or a position of the first target image in a display picture is different from that of the second target image. The first region represents a region within an outer contour of the first target image and not overlapping with the second target image.
    Type: Application
    Filed: January 5, 2026
    Publication date: May 7, 2026
    Inventors: Wenyu LI, Jian ZHANG, Shou LI, Shuyan MA, Xiaoning JIANG, Jing ZHANG, Yingbo GAO, Zhanchang BU, Site CAI, Tianyang HAN
  • Publication number: 20260033848
    Abstract: A method for sonothrombolysis mediated with contrast agents includes administering at least one contrast agent into a blood vessel of a patient. The method further includes controlling application of ultrasound energy to the at least one contrast agent within the blood vessel, wherein controlling the application of the ultrasound energy includes driving an ultrasound transducer with a signal having a first frequency component and a second frequency component different from the first frequency component.
    Type: Application
    Filed: August 7, 2023
    Publication date: February 5, 2026
    Inventors: Xiaoning Jiang, Zhen Xu, Bohua Zhang, Huaiyu Wu, Jinwook Kim, Howuk Kim, Paul Alexander Dayton, Leela Goel
  • Patent number: 12518725
    Abstract: A display device and a display method the display device includes: a memory for storing at least one pre-stored image; and a controller for: obtaining first and second target images according to at least one pre-stored image; and controlling a display module, according to a first control instruction, to display the second target image and hide a display of at least one first sub-region in a first region in a frame displayed after switching from the first target image to the second target image. A size of the first target image is different from that of the second target image, and/or a position of the first target image in a display picture is different from that of the second target image. The first region represents a region within an outer contour of the first target image and not overlapping with the second target image.
    Type: Grant
    Filed: September 30, 2022
    Date of Patent: January 6, 2026
    Assignees: BEIJING BOE DISPLAY TECHNOLOGY CO., LTD., BOE Technology Group Co., Ltd.
    Inventors: Wenyu Li, Jian Zhang, Shou Li, Shuyan Ma, Xiaoning Jiang, Jing Zhang, Yingbo Gao, Zhanchang Bu, Site Cai, Tianyang Han
  • Publication number: 20250288307
    Abstract: The present invention relates to vortex ultrasound transducers and methods of therapeutic ultrasound treatment. A device for therapeutic ultrasound treatment includes a jacket for insertion within a blood vessel of a patient and an ultrasound transducer located within the jacket and comprising a plurality of active elements that are arranged such that, when activated, the ultrasound transducer is configured to generate ultrasound energy with a swirling movement that produces a mechanical shear stress over a target area within the blood vessel of the patient.
    Type: Application
    Filed: April 21, 2023
    Publication date: September 18, 2025
    Inventors: Xiaoning Jiang, Chengzhi Shi, Howuk Kim, Bohua Zhang, Huaiyu Wu
  • Patent number: 12367843
    Abstract: The present disclosure provides a standby control signal generation circuit, including: an amplification sub-circuit connected with an input terminal of the standby control signal generation circuit and configured to receive a video signal and amplify the video signal; an XOR sub-circuit connected with the amplification sub-circuit and configured to perform an XOR operation on the amplified video signal and a ground signal; and an adjustment sub-circuit connected with the XOR sub-circuit and configured to perform a proportional adjustment on an amplitude of an output signal of the XOR sub-circuit to generate a standby control signal. The present disclosure further provides a display driving device, a display driving method and a display apparatus.
    Type: Grant
    Filed: August 30, 2022
    Date of Patent: July 22, 2025
    Assignees: Beijing BOE Display Technology Co., Ltd., BOE TECHNOLOGY GROUP CO., LTD.
    Inventors: Jing Zhang, Jian Zhang, Yingbo Gao, Hongsheng Gu, Xiaoning Jiang, Wenyu Li, Xingliang Li, Liuyun Lv, Shuyan Ma, Yuanpei Zhao
  • Publication number: 20250228576
    Abstract: A device for therapeutic ablative treatment of residual plaque on, in, and/or surrounding a stent within a blood vessel of a subject includes a jacket configured for insertion within a stent within a blood vessel of a subject. The device further includes an ultrasound transducer located within the jacket and having at least one active element oriented to deliver ultrasound energy in a radial and/or axial direction of the jacket from within the stent to ablate the residual plaque.
    Type: Application
    Filed: March 21, 2023
    Publication date: July 17, 2025
    Inventors: Xiaoning Jiang, Howuk Kim, Xuming Dai
  • Publication number: 20250205467
    Abstract: A novel localized, mechanical HIFU (LM-HIFU) transcatheter device that can ablate cancer cells and disrupt the stromal barrier in tumors, enhancing the efficacy of therapeutics and increasing immune cell infiltration. A miniaturized dual-lumen catheter device is configured to deliver M-HIFU to a tumor that does not have the anatomic limitations of conventional HIFU, and enables access to a primary or metastatic tumor regardless of the location.
    Type: Application
    Filed: March 28, 2023
    Publication date: June 26, 2025
    Inventors: Herbert Kim Lyerly, Takuya Osada, Zachary C. Hartman, Pei Zhong, Kamran Mahmood, Xiaoning Jiang, Howuk Kim
  • Publication number: 20250114072
    Abstract: A wearable ultrasound device may include an array of ultrasound transducers, wherein each ultrasound transducer comprises: a matching layer on a top side, an active layer adjacent the matching layer, a first backing layer adjacent the active layer, a second backing layer adjacent the first backing layer; and an epoxy bonding material interspaced between each of the matching layer, the active layer, the first backing layer, and the second backing layer, wherein the array of ultrasound transducers is surrounded by a PDMS filling, whereby the active layer is configured to communicate a signal in response to mechanical deformation.
    Type: Application
    Filed: October 9, 2024
    Publication date: April 10, 2025
    Inventors: Nitin Sharma, Xiaoning Jiang, Xiangming Xue, Sunho Moon
  • Publication number: 20250095597
    Abstract: The present disclosure provides a standby control signal generation circuit, including: an amplification sub-circuit connected with an input terminal of the standby control signal generation circuit and configured to receive a video signal and amplify the video signal; an XOR sub-circuit connected with the amplification sub-circuit and configured to perform an XOR operation on the amplified video signal and a ground signal; and an adjustment sub-circuit connected with the XOR sub-circuit and configured to perform a proportional adjustment on an amplitude of an output signal of the XOR sub-circuit to generate a standby control signal. The present disclosure further provides a display driving device, a display driving method and a display apparatus.
    Type: Application
    Filed: August 30, 2022
    Publication date: March 20, 2025
    Inventors: Jing ZHANG, Jian ZHANG, Yingbo GAO, Hongsheng GU, Xiaoning JIANG, Wenyu LI, Xingliang LI, Liuyun LV, Shuyan MA, Yuanpei ZHAO
  • Publication number: 20250064469
    Abstract: A catheter-implemented transducer device for intravascular thrombolysis, is described herein. Such a transducer device includes a catheter defining a longitudinal axis and having opposed proximal and distal ends. At least one ultrasonic transducer arrangement is disposed about the distal end. The ultrasonic transducer arrangement is oriented with acoustic waves propagating parallel or perpendicular to the longitudinal axis. Optionally, the ultrasonic transducer arrangement is configured as a multi-layer stacked structure of ultrasonic transducer elements. Optionally, the ultrasonic transducer arrangement is a laser ultrasonic transducer arrangement. Optionally, the ultrasonic transducer arrangement is configured to operate in a lateral mode.
    Type: Application
    Filed: July 3, 2024
    Publication date: February 27, 2025
    Inventors: Xiaoning Jiang, Jinwook Kim, Jianguo Ma, Xuming Dai
  • Patent number: 12229506
    Abstract: A method and a system for filtering ill corpus are provided. The method includes following steps: acquiring a text corpus to be recognized, and preprocessing the text corpus to be recognized to obtain a basic text corpus; extracting entities in the basic text corpus, and performing matching search on the entities of the basic text corpus according to an ill-text knowledge graph to obtain a first recognition result; detecting and recognizing the basic text corpus according to a corpus recognition model to obtain a second recognition result; and filtering the text corpus to be recognized according to the first or/and the second recognition result, and updating the ill-text knowledge graph according to the second recognition result. With semantic network essence and strong correlation ability of knowledge graph technology, candidate ill entities can be obtained, thus facilitating filtering of obscure ill information in forms of pinyin, homophonic words and split words.
    Type: Grant
    Filed: December 16, 2022
    Date of Patent: February 18, 2025
    Assignee: Zhejiang Gongshang University
    Inventors: Xiaoning Jiang, Kai Liu, Yuhan Zhou, Hongmin Xie, Yukuan He, Weijie Liu, Jie Zhang, Zhen Liu
  • Publication number: 20250017608
    Abstract: A method for disrupting a blood clot with ultrasound and at least one cavitation enhancing agent includes administering at least one cavitation enhancing agent into a blood vessel of a subject. The method further includes monitoring the at least one cavitation enhancing agent to determine when at least a portion of the at least one cavitation enhancing agent has reached a blood clot. The method further includes controlling application of ultrasound energy to the at least one cavitation enhancing agent within the blood vessel of the subject such that, during a first time period, cavitation-enhancing ultrasound energy is not applied to the at least one cavitation enhancing agent within the blood vessel and, during a second time period after the first time period, cavitation enhancing ultrasound energy is applied to the at least one cavitation enhancing agent within the blood vessel.
    Type: Application
    Filed: December 1, 2022
    Publication date: January 16, 2025
    Inventors: Paul Alexander Dayton, Jinwook KIM, Xiaoning Jiang, Bohua Zhang, Huaiyu Wu, Zhen Xu
  • Patent number: 12199995
    Abstract: A system and method for authentication code generation based on adversarial machine learning are provided in this disclosure. The method includes a defensive authentication code generation system, an authentication code formation module, an authentication code scheduling module, an authentication-code adversarial processing center, an attack sample generation module, a verification and error reporting system, a division module, a grouping and distribution system, a category checking module, a data recording unit, a detection module and an integration terminal. In the system and method for authentication code generation based on adversarial machine learning according to the disclosure, attack scenes are simulated for continuous training for the authentication code, error-reporting data are recorded and optimized into the defensive authentication code generation system, so as to improve defense performance of the authentication code.
    Type: Grant
    Filed: December 22, 2022
    Date of Patent: January 14, 2025
    Assignee: Zhejiang Gongshang University
    Inventors: Xiaoning Jiang, Jianan Qi, Jian Fang, Yuhan Zhou, Hongmin Xie, Hanqi Liu, Zhenye Xu
  • Publication number: 20240374240
    Abstract: Ultrasound systems and methods of use are provided for rapidly heating a target area of a subject. The ultrasound system can include at least one imaging transducer array for imaging the target area, and at least two spaced-apart heating transducer arrays for heating the target area. The heating transducer arrays can be separated by the imaging transducer array on an ultrasound probe.
    Type: Application
    Filed: September 9, 2022
    Publication date: November 14, 2024
    Applicants: University of Pittsburgh - Of the Commonwealth System of Higher Education, North Carolina State University, Blatek Industries, Inc.
    Inventors: Kim Kang, Qiyang Chen, Zhiyu Sheng, Bohua Zhang, Howuk Kim, Huaiyu Wu, Xiaoning Jiang, Mengyue Chen, Xuecang Geng
  • Publication number: 20240153472
    Abstract: The present disclosure provides a display device and a display method. The display device includes: a memory for storing at least one pre-stored image; and a controller for: obtaining first and second target images according to the at least one pre-stored image; and controlling a display module, according to a first control instruction, to display the second target image and hide a display of at least one first sub-region in a first region in a frame displayed after switching from the first target image to the second target image. A size of the first target image is different from that of the second target image, and/or a position of the first target image in a display picture is different from that of the second target image. The first region represents a region within an outer contour of the first target image and not overlapping with the second target image.
    Type: Application
    Filed: September 30, 2022
    Publication date: May 9, 2024
    Inventors: Wenyu Li, Jian Zhang, Shou Li, Shuyan Ma, Xiaoning Jiang, Jing Zhang, Yingbo Gao, Zhanchang Bu, Site Cai, Tianyang Han
  • Publication number: 20240106841
    Abstract: A system and method for authentication code generation based on adversarial machine learning are provided in this disclosure. The method includes a defensive authentication code generation system, an authentication code formation module, an authentication code scheduling module, an authentication-code adversarial processing center, an attack sample generation module, a verification and error reporting system, a division module, a grouping and distribution system, a category checking module, a data recording unit, a detection module and an integration terminal. In the system and method for authentication code generation based on adversarial machine learning according to the disclosure, attack scenes are simulated for continuous training for the authentication code, error-reporting data are recorded and optimized into the defensive authentication code generation system, so as to improve defense performance of the authentication code.
    Type: Application
    Filed: December 22, 2022
    Publication date: March 28, 2024
    Inventors: Xiaoning Jiang, Jianan QI, Jian Fang, Yuhan Zhou, Hongmin Xie, Hanqi Liu, Zhenye Xu
  • Publication number: 20240037328
    Abstract: A method and a system for filtering ill corpus are provided. The method includes following steps: acquiring a text corpus to be recognized, and preprocessing the text corpus to be recognized to obtain a basic text corpus; extracting entities in the basic text corpus, and performing matching search on the entities of the basic text corpus according to an ill-text knowledge graph to obtain a first recognition result; detecting and recognizing the basic text corpus according to a corpus recognition model to obtain a second recognition result; and filtering the text corpus to be recognized according to the first or/and the second recognition result, and updating the ill-text knowledge graph according to the second recognition result. With semantic network essence and strong correlation ability of knowledge graph technology, candidate ill entities can be obtained, thus facilitating filtering of obscure ill information in forms of pinyin, homophonic words and split words.
    Type: Application
    Filed: December 16, 2022
    Publication date: February 1, 2024
    Applicant: Zhejiang Gongshang University
    Inventors: Xiaoning JIANG, Kai LIU, Yuhan ZHOU, Hongmin XIE, Yukuan HE, Weijie LIU, Jie ZHANG, Zhen LIU
  • Patent number: 11883679
    Abstract: The disclosure provides systems for ultrasound-induced thrombolysis with magnetic microbubbles under a rotational/alternating magnetic field, sonothrombolysis systems with magnetic microbubbles and optional nanodroplets for inducing thrombolysis under an acoustic field, and a rotational/alternating magnetic field, and methods of treating patients with blood clots using the sonothrombolysis systems of the present disclosure.
    Type: Grant
    Filed: October 12, 2020
    Date of Patent: January 30, 2024
    Assignee: North Carolina State University
    Inventors: Xiaoning Jiang, Bohua Zhang
  • Patent number: 11877517
    Abstract: Disclosed are various embodiments for a piezo-composite transducer that is flexible such that it may conform to regular or irregular shapes. A flexible piezo-composite transducer may include an active piezoelectric material, such as PZT-5H, and a passive polymer matrix formed of a flexible material, such as polydimethylsiloxane (PDMS). The flexible piezo-composite transducer may include a first side and a second side, where each of the first side and the second side include a first electrode and a second electrode deposited thereon, respectively. At least one of the first electrode and the second electrode may include a silver nanowire (AgNW) and PDMS electrode that is flexible.
    Type: Grant
    Filed: March 4, 2020
    Date of Patent: January 16, 2024
    Assignee: North Carolina State University
    Inventors: Xiaoning Jiang, Taeyang Kim, Yong Zhu