Patents by Inventor Xiaoning Wu

Xiaoning Wu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220251670
    Abstract: Methods for the rapid detection of the presence or absence of Epstein Barr Virus (EBV) in a biological or non-biological sample are described. The methods can include performing an amplifying step, a hybridizing step, and a detecting step. Furthermore, primers and probes targeting EBV, and kits are provided that are designed for the detection of target regions of EBV. Also described are kits, reaction mixtures, and oligonucleotides (e.g., primer and probe) for the amplification and detection of EBV. Also described are primers and probes that detect different regions of EBV, and can be employed in a dual target assay for simultaneously detecting two different and non-overlapping target regions of EBV.
    Type: Application
    Filed: July 24, 2020
    Publication date: August 11, 2022
    Inventors: Aaron T. Hamilton, Marintha Heil, Debra Liggett, Jingtao Sun, Ling Wang, Xiaoning Wu
  • Patent number: 10889869
    Abstract: Methods for the rapid detection of the presence or absence of Herpes simplex virus 1 and 2 (HSV-1 and HSV-2) in a biological or non-biological sample are described. The methods can include performing an amplifying step, a hybridizing step, and a detecting step. Furthermore, primers, probes targeting the genes for HSV-1 viral DNA polymerase B (HSV-1 Pol) and HSV-1 thymidine kinase C (HSV-1 TK), and also target the genes for HSV-2 thymidine kinase C (HSV-2 TK) and HSV-2 glycoprotein B (HSV-2 gB), along with kits are provided that are designed for the detection of HSV-1 and/or HSV-2.
    Type: Grant
    Filed: April 23, 2018
    Date of Patent: January 12, 2021
    Assignee: Roche Molecular Systems, Inc.
    Inventors: Xiaoning Wu, Karen Young
  • Patent number: 10689718
    Abstract: A method of simultaneously amplifying genotypes 1, 2, 3 and/or 4 of HEV is disclosed comprising amplifying the genotypes 1, 2, 3 and/or 4 of HEV with one single none-degenerate forward primer partially overlapping the 5?UTR region of HEV and at least one reverse primer. Also disclosed are related methods comprising a probe, and kits for the detection of genotypes 1, 2, 3 and/or 4 of HEV.
    Type: Grant
    Filed: June 2, 2017
    Date of Patent: June 23, 2020
    Assignee: Roche Molecular Systems, Inc.
    Inventors: Hermann Leying, Thomas W. Myers, Nicolas Newton, Eberhard Russmann, Joseph San Filippo, Nancy Schoenbrunner, Heike Wilts, Xiaoning Wu, Karen K. Y. Young, Dirk Zimmermann
  • Patent number: 10272643
    Abstract: A multi-layer synthetic graphite conductor. The multi-layer synthetic graphite conductor can include: a set of synthetic graphite sheets; and a perimeter wall for protecting the synthetic graphite sheets.
    Type: Grant
    Filed: October 26, 2015
    Date of Patent: April 30, 2019
    Assignee: Jones Tech (USA), Inc.
    Inventor: Xiaoning Wu
  • Patent number: 10262916
    Abstract: Disclosed is a foldable graphite heat spreader for reducing the internal temperature of an electronic device. The foldable graphite heat spreader includes a multi-layer graphite lamination having a top surface, a bottom surface and a corrugated surface along the bending areas of the electronic device. The multi-layer graphite lamination spreads heat on the hot spots or takes heat away the components of the electronic device. The top surface includes a first top end and a second top end. The bottom surface includes a first bottom end and a second bottom end. The corrugated surface includes a top corrugated surface and a bottom corrugated surface and have spring characteristic to expand when bending, to contract back its original shape when no bending. The foldable graphite heat spreader includes a protective plastic film for providing protection to the top surface and the top corrugated surface of the multi-layer graphite lamination from dropping particles of graphite.
    Type: Grant
    Filed: December 20, 2016
    Date of Patent: April 16, 2019
    Assignee: JONES TECH INC.
    Inventor: Xiaoning Wu
  • Patent number: 10125402
    Abstract: Methods for the measuring cell-free nucleic acids and/or virus particles from dried blood spots are described. The methods can include the steps of rehydrating a dried blood sample, optionally fixing cells present in the rehydrated dried blood sample, eluting cell-free virus particles from the rehydrated dried blood sample, separating the cell-free viruses from any cell debris that may be present in the rehydrated dried blood sample by way of a filter, and measuring cell-free virus particles by a viral particle quantification technique.
    Type: Grant
    Filed: October 20, 2014
    Date of Patent: November 13, 2018
    Assignee: ROCHE MOLECULAR SYSTEMS, INC.
    Inventors: Paul Baum, Megan M. Crask, Xiaoning Wu
  • Publication number: 20180259271
    Abstract: Providing a thermal interface structure can include: forming a thermal interface material for thermally coupling a heat-generating structure to a heat-dissipating structure such that the thermal interface material capable of enduring a repeated shearing force caused by sliding the heat-generating structure against the heat-dissipating structure; and forming an adhesive material for holding the thermal interface material in place on the heat-dissipating structure.
    Type: Application
    Filed: March 10, 2017
    Publication date: September 13, 2018
    Inventor: Xiaoning Wu
  • Publication number: 20180245168
    Abstract: Methods for the rapid detection of the presence or absence of Herpes simplex virus 1 and 2 (HSV-1 and HSV-2) in a biological or non-biological sample are described. The methods can include performing an amplifying step, a hybridizing step, and a detecting step. Furthermore, primers, probes targeting the genes for HSV-1 viral DNA polymerase B (HSV-1 Pol) and HSV-1 thymidine kinase C (HSV-1 TK), and also target the genes for HSV-2 thymidine kinase C (HSV-2 TK) and HSV-2 glycoprotein B (HSV-2 gB), along with kits are provided that are designed for the detection of HSV-1 and/or HSV-2.
    Type: Application
    Filed: April 23, 2018
    Publication date: August 30, 2018
    Inventors: Xiaoning Wu, Karen Young
  • Publication number: 20180199460
    Abstract: Disclosed is a graphite-over-foam structure for increasing heat conductivity between the heat spreader and the heat source. The graphite-over-foam structure includes a first foam core unit, a first graphite layer, a second foam core unit, a second graphite layer and a first bonding adhesive. The first foam core unit is configured to fill the air gap between the heat spreader and the heat source. The first graphite layer is wrapped around the first foam to do heat-conducting function between the heat source and the heat spreader. The second foam core unit is positioned next to the first foam core unit to fill the air gap between the heat spreader and the heat source. The second graphite layer is wrapped around the second foam core unit and bonded with the first graphite layer to create a first cross-section to expand the heat conducting paths.
    Type: Application
    Filed: January 7, 2017
    Publication date: July 12, 2018
    Applicant: JONES TECH INC.
    Inventor: XIAONING WU
  • Publication number: 20180177074
    Abstract: Disclosed is a foldable graphite heat spreader for reducing the internal temperature of an electronic device. The foldable graphite heat spreader includes a multi-layer graphite lamination having a top surface, a bottom surface and a corrugated surface along the bending areas of the electronic device. The multi-layer graphite lamination spreads heat on the hot spots or takes heat away the components of the electronic device. The top surface includes a first top end and a second top end. The bottom surface includes a first bottom end and a second bottom end. The corrugated surface includes a top corrugated surface and a bottom corrugated surface and have spring characteristic to expand when bending, to contract back its original shape when no bending. The foldable graphite heat spreader includes a protective plastic film for providing protection to the top surface and the top corrugated surface of the multi-layer graphite lamination from dropping particles of graphite.
    Type: Application
    Filed: December 20, 2016
    Publication date: June 21, 2018
    Applicant: JONES TECH INC.
    Inventor: XIAONING WU
  • Patent number: 9982313
    Abstract: Methods for the rapid detection of the presence or absence of Herpes simplex virus 1 and 2 (HSV-1 and HSV-2) in a biological or non-biological sample are described. The methods can include performing an amplifying step, a hybridizing step, and a detecting step. Furthermore, primers, probes targeting the genes for HSV-1 viral DNA polymerase B (HSV-1 Pol) and HSV-1 thymidine kinase C (HSV-1 TK), and also target the genes for HSV-2 thymidine kinase C (HSV-2 TK) and HSV-2 glycoprotein B (HSV-2 gB), along with kits are provided that are designed for the detection of HSV-1 and/or HSV-2.
    Type: Grant
    Filed: August 17, 2012
    Date of Patent: May 29, 2018
    Assignee: Roche Molecular Systems, Inc.
    Inventors: Xiaoning Wu, Karen Young
  • Publication number: 20180084682
    Abstract: Shielding an electronic circuit can include: forming an absorbing material around a perimeter of the electronic circuit such that the absorbing material provides a shielding wall that isolates the electronic circuit from electromagnetic interference; forming a conductive top cover over the absorbing material and the electronic circuit such that the conductive top cover provides a reflection loss for electromagnetic interference; and forming a grounding pad for electrically grounding the conductive top cover.
    Type: Application
    Filed: September 20, 2016
    Publication date: March 22, 2018
    Inventor: Xiaoning Wu
  • Publication number: 20170268074
    Abstract: A method of simultaneously amplifying genotypes 1, 2, 3 and/or 4 of HEV is disclosed comprising amplifying the genotypes 1, 2, 3 and/or 4 of HEV with one single none-degenerate forward primer partially overlapping the 5?UTR region of HEV and at least one reverse primer. Also disclosed are related methods comprising a probe, and kits for the detection of genotypes 1, 2, 3 and/or 4 of HEV.
    Type: Application
    Filed: June 2, 2017
    Publication date: September 21, 2017
    Inventors: Hermann Leying, Thomas W. Myers, Nicolas Newton, Eberhard Russmann, Joseph San Filippo, Nancy Schoenbrunner, Heike Wilts, Xiaoning Wu, Karen K. Y. Young, Dirk Zimmermann
  • Patent number: 9702017
    Abstract: A method of simultaneously amplifying genotypes 1, 2, 3 and/or 4 of HEV is disclosed comprising amplifying the genotypes 1, 2, 3 and/or 4 of HEV with one single none-degenerate forward primer partially overlapping the 5?UTR region of HEV and at least one reverse primer. Also disclosed are related methods comprising a probe, and kits for the detection of genotypes 1, 2, 3 and/or 4 of HEV.
    Type: Grant
    Filed: April 17, 2013
    Date of Patent: July 11, 2017
    Inventors: Hermann Leying, Thomas W. Myers, Nicolas Newton, Eberhard Russmann, Joseph San Filippo, Nancy Schoenbrunner, Heike Wilts, Xiaoning Wu, Karen K. Y. Young, Dirk Zimmermann
  • Publication number: 20170114455
    Abstract: A thermally conductive composition having an electrically conductive filler with a ceramic coating selected to provide a relatively high dielectric breakdown voltage of the thermally conductive composition while maintaining a relatively high thermal conductivity of the thermally conductive composition.
    Type: Application
    Filed: October 26, 2015
    Publication date: April 27, 2017
    Inventor: Xiaoning Wu
  • Publication number: 20170113438
    Abstract: A multi-layer synthetic graphite conductor. The multi-layer synthetic graphite conductor can include: a set of synthetic graphite sheets; and a perimeter wall for protecting the synthetic graphite sheets.
    Type: Application
    Filed: October 26, 2015
    Publication date: April 27, 2017
    Inventor: Xiaoning Wu
  • Publication number: 20170089650
    Abstract: A heat transfer structure, including: a plurality of layers of graphite material each having a shape selected for providing a thermal path between a hotspot in an electronic device and a heat dissipating structure of the electronic device; and a set of intervening bonding layers for coupling together the layers of graphite material such that the heat transfer structure has a flexible body for avoiding mechanical stress on the hotspot when the heat transfer structure is coupled between the hotspot and the heat dissipating structure.
    Type: Application
    Filed: September 24, 2015
    Publication date: March 30, 2017
    Inventor: Xiaoning Wu
  • Publication number: 20170089648
    Abstract: An adhesive-thermal gasket, including: a body of thermally conductive material having a set of openings formed through the body; and an adhesive disposed into each opening for holding together a heat-generating component and a heat-dissipating structure as the body thermally couples the heat-generating component to the heat-dissipating structure.
    Type: Application
    Filed: September 24, 2015
    Publication date: March 30, 2017
    Inventor: Xiaoning Wu
  • Publication number: 20160343466
    Abstract: A multi-layer synthetic graphite conductor, including: forming a body of the synthetic graphite conductor comprising multiple layers of a synthetic graphite sheet; and forming at least one structure through the layers for maintaining a high thermal conductivity by enabling high thermal conduction between the layers.
    Type: Application
    Filed: May 20, 2015
    Publication date: November 24, 2016
    Inventor: Xiaoning Wu
  • Publication number: 20150232955
    Abstract: Methods for the measuring cell-free nucleic acids and/or virus particles from dried blood spots are described. The methods can include the steps of rehydrating a dried blood sample, optionally fixing cells present in the rehydrated dried blood sample, eluting cell-free virus particles from the rehydrated dried blood sample, separating the cell-free viruses from any cell debris that may be present in the rehydrated dried blood sample by way of a filter, and measuring cell-free virus particles by a viral particle quantification technique.
    Type: Application
    Filed: October 20, 2014
    Publication date: August 20, 2015
    Inventors: Paul Baum, Megan M. Crask, Xiaoning Wu