Abstract: A confocal laser fundus angiographic device, comprises: an objective lens, a scanning lens, a scanning galvanometer, a mirror, a filtering module, an imaging detection assembly and an excitation light source. The illumination light emitted by the excitation light source enters the fundus passing through the scanning galvanometer, the scanning lens and the objective lens. Fluorescent substances in fundus vessels are excited by the illumination light and emit light with a specific wavelength. The light with a specific wavelength enters the imaging detection assembly by passing through the objective lens, the scanning lens, the scanning galvanometer, the mirror and the filtering module. The filtering module comprises a base, a motor mounted on the base, a rotary block mounted on the motor and at least one filter mounted on the rotary block. The base is provided with a light-through hole.

Abstract: Described are compounds which bind to aspartic proteases to inhibit their activity. They are useful in the treatment or amelioration of diseases associated with aspartic protease activity. Also described are methods of use of the compounds described herein in ameliorating or treating aspartic protease related disorders in a subject in need thereof.

Abstract: Disclosed are compounds according to Formula I: wherein the variables are defined herein. Such compounds are can bind aspartic proteases to inhibit their activity. They are useful in the treatment or amelioration of diseases associated with aspartic protease activity. Also described herein are methods of antagonizing aspartic protease inhibitors in a subject in need thereof comprising administering to the subject a therapeutically effective amount of a compound according to Formula I.