Abstract: An ultrasound responsive lipid nanoparticle carrying genes and a cell membrane is provided, which can simultaneously carry small molecule nucleic acids and a cell membrane, and can be used as a gene transfection carrier in vivo. Its surface is connected with small molecule nucleic acids based on the principle of charge adsorption, a component of a cell membrane is mixed in a surface lipid layer, PFP is encapsulated inside the nanoparticle, liquid gas phase transition occurs under ultrasonic irradiation, and blasting occurs under continuous ultrasonic irradiation, the blasting energy generated forms reversible acoustic holes on the surface of the cell membrane, and a drug released after blasting is driven by a blasting driving force to directly enter an interior of the cell through the acoustic holes, realizing an efficient release and transfection of nucleic acids in the cell.

Abstract: An ultrasound responsive lipid nanoparticle carrying genes and a cell membrane is provided, which can simultaneously carry small molecule nucleic acids and a cell membrane, and can be used as a gene transfection carrier in vivo. Its surface is connected with small molecule nucleic acids based on the principle of charge adsorption, a component of a cell membrane is mixed in a surface lipid layer, PFP is encapsulated inside the nanoparticle, liquid gas phase transition occurs under ultrasonic irradiation, and blasting occurs under continuous ultrasonic irradiation, the blasting energy generated forms reversible acoustic holes on the surface of the cell membrane, and a drug released after blasting is driven by a blasting driving force to directly enter an interior of the cell through the acoustic holes, realizing an efficient release and transfection of nucleic acids in the cell.

Abstract: A toaster includes a housing having a toasting chamber therein. An upper end of the toasting chamber has an inlet for feeding sliced bread. A lower end of the toasting chamber has an outlet for discharging the sliced bread. The outlet is provided with a door for opening and closing the outlet. The door is driven by a door opening structure. The door opening structure includes a door locking mechanism, a lift door opening mechanism, a magnetic suction mechanism, a power switch mechanism, and a PCB control board.

Abstract: A toaster includes a housing having a toasting chamber therein. An upper end of the toasting chamber has an inlet for feeding sliced bread. A lower end of the toasting chamber has an outlet for discharging the sliced bread. The outlet is provided with a door for opening and closing the outlet. The door is driven by a door opening structure. The door opening structure includes a door locking mechanism, a lift door opening mechanism, a magnetic suction mechanism, a power switch mechanism, and a PCB control board.