Patents by Inventor Xiaoping LUO

Xiaoping LUO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240052026
    Abstract: Related to the field of bioformulations, disclosed is a stable antibody formulation, including an anti-IL-17 antibody, a buffer, a stabilizer, and a surfactant. The stabilizer is methionine or a combination of methionine and a sugar alcohol. The pH value of the antibody formulation is 5.4-6.6. The antibody formulation has improved stability at high temperature and room temperature, can be kept in a liquid form, and is convenient to use.
    Type: Application
    Filed: December 21, 2021
    Publication date: February 15, 2024
    Inventors: Yili YANG, Xiaoping LUO, Qingrui LI, Zixuan KOU, Yong WU, Cuihua LIU
  • Publication number: 20230414156
    Abstract: An electrophysiological mapping catheter device (10) includes a catheter, an adjusting handle device, electrodes, and a connector. The catheter includes an adjusting tube and a plurality of branch tubes. Two ends of each branch tube are respectively a connection end and a detection end. The detection ends are arranged in a staggered manner. The electrodes are respectively disposed on the detection ends, and the connection ends are connected to the adjusting tube. The adjusting tube is connected to the adjusting handle device. The adjusting handle device is capable of adjusting a bending angle of the adjusting tube. The connector is disposed on the adjusting handle device and is electrically connected to the electrodes. The connector is further configured to be connected with an electrophysiological system for transmitting electrical signals detected by the electrodes.
    Type: Application
    Filed: July 29, 2021
    Publication date: December 28, 2023
    Inventors: Xingpeng LIU, Jingzhong SONG, Mingfang ZHANG, Xiaoping LUO, Jun MAO
  • Publication number: 20100015669
    Abstract: Provided is a method for constructing microRNA adenovirus expression plasmids comprising severe hepatitis related genes of hfgl2 (Human Fibrinogen-like protein 2) prothrombinase, Fas and TNFR1 (tumor necrosis factor receptor 1), and the specificity and effectivity of microRNA interference plasmids are detected at cellular level so that a combined use of three microRNA adenovirus expression plasmids for the treatment of severe hepatitis can be achieved. According to the present invention, pAd/CMV/V5-DEST vectors and pcDNA expression plasmid of hfgl2, hFas and hTNFR1 are used to construct pAd-hfgl2, pAd-hFas and pAd-hTNFR1 by means of Gateway technology.
    Type: Application
    Filed: November 12, 2008
    Publication date: January 21, 2010
    Inventors: Qin NING, Xiaoping LUO, Dong XI, Sui GAO, Chuanlong ZHU, Jianwen GUO, Weiming YAN, Ming WANG
  • Publication number: 20080300147
    Abstract: The present invention provides a method for detecting a fibrotic disorder in a subject by: (a) providing a biological sample obtained from the subject (such as endometrium, peritoneal fluid, and/or smooth muscle cells); (b) analyzing the expression of at least one gene that is differentially expressed in the fibrotic disorder of interest; and (c) correlating the expression of the gene(s) with the presence or absence of the fibrotic disorder in the subject. The present invention also provides a method and compositions for modulating the expression of genes that are differentially expressed in fibrotic tissues, compared to normal tissues. Restoration of gene expression to levels associated with normal tissue is expected to ameliorate at least some of the symptoms of the fibrotic disorder. This method includes the step of contacting the tissue with an agent that modulates expression of one or more differentially expressed genes in the tissue.
    Type: Application
    Filed: March 28, 2005
    Publication date: December 4, 2008
    Inventors: Nasser Chegini, Xiaoping Luo, Li Ding, R. Stan Williams