Patents by Inventor Xiaoping Tu

Xiaoping Tu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Human coagulation factor IX (FIX) fusion protein, preparation method therefor, and use thereof
    Patent number: 11472863
    Abstract: A hyperglycosylated recombinant human coagulation factor IX (FIX) fusion protein, a preparation method therefor, and use thereof. The fusion protein sequentially comprises, from N- to C-terminus, a human FIX, a flexible peptide linker, at least one human chorionic gonadotropin ? subunit carboxy-terminal peptide rigid unit, and a half-life extending moiety. The fusion protein has a biological activity similar to that of the recombinant FIX, an extended in vivo activity half-life, and reduced immunogenicity, so as to improve pharmacokinetics and pharmacodynamics.
    Type: Grant
    Filed: April 10, 2017
    Date of Patent: October 18, 2022
    Assignees: Ampsource Biopharma Shanghai Inc., Pharmab, Inc.
    Inventors: YongJuan Gao, Si Chen, Zirui Li, Xiaoping Tu, Bill Nai-chau Sun, Qiang Li
  • HUMAN COAGULATION FACTOR IX (FIX) FUSION PROTEIN, PREPARATION METHOD THEREFOR, AND USE THEREOF
    Publication number: 20200157185
    Abstract: A hyperglycosylated recombinant human coagulation factor IX (FIX) fusion protein, a preparation method therefor, and use thereof. The fusion protein sequentially comprises, from N- to C-terminus, a human FIX, a flexible peptide linker, at least one human chorionic gonadotropin ? subunit carboxy-terminal peptide rigid unit, and a half-life extending moiety. The fusion protein has a biological activity similar to that of the recombinant FIX, an extended in vivo activity half-life, and reduced immunogenicity, so as to improve pharmacokinetics and pharmacodynamics.
    Type: Application
    Filed: April 10, 2017
    Publication date: May 21, 2020
    Inventors: YongJuan Gao, Si Chen, Zirui Li, Xiaoping Tu, Bill Nai-chau Sun, Qiang Li
  • Service sending, receiving methods and devices
    Patent number: 9882645
    Abstract: Provided are service sending, receiving methods and devices.
    Type: Grant
    Filed: June 16, 2014
    Date of Patent: January 30, 2018
    Assignee: XI'AN ZHONGXING NEW SOFTWARE CO. LTD.
    Inventors: Fen Yan, Xiaoping Tu, Huilong Xia
  • Service Sending, Receiving Methods and Devices
    Publication number: 20160226589
    Abstract: Provided are service sending, receiving methods and devices.
    Type: Application
    Filed: June 16, 2014
    Publication date: August 4, 2016
    Applicant: ZTE CORPORATION
    Inventors: Fen YAN, Xiaoping TU, Huilong XIA
  • Method and apparatus for regulating service of optical synchronous digital hierarchy network
    Patent number: 8548324
    Abstract: The present invention discloses a method and an apparatus for adjusting a service of optical synchronous digital hierarchy network, and the method comprises: at first configuring the input time-slot space-division cross path to the time-division module after adjustment in space-division module and the time-division cross path of the time-division module after adjustment; and configuring the output time-slot space-division cross path from the time-division module after adjustment in space-division module; deleting the original cross path formed by the time-division module before adjustment.
    Type: Grant
    Filed: September 11, 2009
    Date of Patent: October 1, 2013
    Assignee: ZTE Corporation
    Inventors: Xiaoping Tu, Jun Lv
  • METHOD AND APPARATUS FOR REGULATING SERVICE OF OPTICAL SYNCHRONOUS DIGITAL HIERARCHY NETWORK
    Publication number: 20110249974
    Abstract: The present invention discloses a method and an apparatus for adjusting a service of optical synchronous digital hierarchy network, and the method comprises: at first configuring the input time-slot space-division cross path to the time-division module after adjustment in space-division module and the time-division cross path of the time-division module after adjustment; and configuring the output time-slot space-division cross path from the time-division module after adjustment in space-division module; deleting the original cross path formed by the time-division module before adjustment.
    Type: Application
    Filed: September 11, 2009
    Publication date: October 13, 2011
    Applicant: ZTE CORPORATION
    Inventors: Xiaoping Tu, Jun Lv