Abstract: Provided are a preparation of semicarbazide-sensitive amine oxidase inhibitor and the use thereof. In particular, disclosed are a compound as shown in formula I, or a stereoisomer or racemate or pharmaceutically acceptable salt thereof. Also disclosed is that the above-mentioned compound can inhibit semicarbazide-sensitive amine oxidase.

Abstract: Provided are a JAK kinase inhibitor, preparation and use thereof. In particular, provided is a compound of Formula I, wherein each group is as described in the specification. The compound has an excellent JAK inhibitory activity, and therefore can be used to prepare pharmaceutical compositions for the treatment of cancer and other diseases related to JAK activity.

Abstract: Provided are a multi-modulation-format compatible space laser communication method and system based on direct modulation, which solve the problems that an existing coherent laser communication system is poor in compatibility and expandability and complex in structure.

Abstract: The present invention provides an image recognition method, an electronic device and a computer-readable storage medium. The method includes: segmenting an original image into a plurality of unit images having the same predetermined size; inputting the unit images into a pre-built neural network model to carry out processing, so as to correspondingly add a detection frame to a marker in each unit image to form a pre-detection unit image; stitching a plurality of pre-detection unit images into a pre-output image according to segmentation positions of each unit image in the original image; determining whether the markers selected in two adjacent detection frames in the pre-output image are the same marker; outputting the image with the detection frames until all the detection frames confirmed to have the same markers are all merged. The present invention can effectively recognize types and positions of the markers in the image.

Abstract: An optical antenna includes a coarse tracking liquid crystal, a coarse tracking liquid crystal controller, a beam shrinking system, a fine tracking liquid crystal, a fine tracking liquid crystal controller, a beam splitter, a first coupling system, a single-mode optical fiber, a second coupling system, a detector and a data analysis and instruction system. The antenna can be configured to receive a laser beam from a communication target and transmit the laser beam to the communication target. The optical antenna realizes the acquisition, tracking and pointing of the space laser beam by cascade connection of two stages of liquid crystal devices. At the same time, the optical antenna has the advantages of fast beam pointing and short response time by utilizing the deflection of the Bi-stable dual-frequency liquid crystals to realize change of high-precision beam pointing.

Abstract: A lightweight scalable multi-user optical antenna includes a coarse tracking liquid crystal, an optical filter, a beam shrinking system, a fine tracking liquid crystal and a beam splitter which are arranged in sequence and are located on a same central axis; further includes a data analysis and instruction system, a coarse tracking liquid crystal controller, a fine tracking liquid crystal controller, j single-mode optical fibers, and an imaging system and a dichroic coupling system which are respectively arranged in two emergent light paths of the beam splitter; and can be used to receive and transmit the laser beams of j communication targets. When the number of users increases, only sub regions of the coarse tracking liquid crystal and the fine tracking liquid crystal need to be added, and no additional components need to be added, and the lightweight scalable multi-user optical antenna has strong scalability.

Abstract: An automatic identification method and an identification system for a gastrointestinal marker are provided. The automatic identification method comprises the following steps: determining a suspected gastrointestinal marker region in an image; removing an overlapping suspected gastrointestinal marker region; and determining whether the suspected gastrointestinal marker region is part of the gastrointestinal marker. In the method, by means of processing and analyzing an image, positions of a gastrointestinal marker in the image can be automatically detected.

Abstract: The present invention relates to a codrug that cleaved in the gut, preparation therefor, and a use thereof. Specifically, provided is a codrug compound in formula I. Also provided are a method of using the present compound for the treatment of gastrointestinal tract autoimmune diseases, inflammatory diseases, and cancers, as well as a method and an intermediate for preparing the present compound.

Abstract: The present invention provides preparation of a semicarbazide-sensitive amine oxidase inhibitor and use thereof. In particular, disclosed in the present invention are a compound as represented by formula I, or a stereoisomer or a racemate or a pharmaceutically acceptable salt of the compound. Also disclosed in the present invention is that the compound can inhibit semicarbazide-sensitive amine oxidase.

Abstract: Provided are a preparation of semicarbazide-sensitive amine oxidase inhibitor and the use thereof. In particular, disclosed are a compound as shown in formula I, or a stereoisomer or racemate or pharmaceutically acceptable salt thereof. Also disclosed is that the above-mentioned compound can inhibit semicarbazide-sensitive amine oxidase.

Abstract: Provided are a JAK kinase inhibitor, preparation and use thereof. In particular, provided is a compound of Formula I, wherein each group is as described in the specification. The compound has an excellent JAK inhibitory activity, and therefore can be used to prepare pharmaceutical compositions for the treatment of cancer and other diseases related to JAK activity.

Abstract: The disclosure relates to a multi-modulation-format compatible high-speed laser signal generation system and method. The disclosure can greatly improve modulation format compatibility of a laser communication system and saves system upgrading costs and resource costs. The system mainly includes a control instruction unit, a serial-parallel changeover switch unit, a precoding switch unit, a power control unit, an IQ modulator, a narrow line width laser, and a bias point control unit, wherein the control instruction unit is respectively connected to the serial-parallel changeover switch unit, the precoding switch unit, the power control unit, and the bias point control unit; the serial-parallel changeover switch unit, the precoding switch unit, the power control unit, and the IQ modulator are electrically connected in sequence; the narrow line width laser is connected to an optical input end of the IQ modulator; and the bias point control unit is connected to the IQ modulator.

Abstract: A phase-lock-free system includes a control instruction unit, a low-noise high-gain optical amplifier, an optical switch, a filter, an optical delay interferometer I, an optical delay interferometer Q, a first balanced detector, a second balanced detector, an anti-coding switch unit, a parallel-serial conversion unit, and a data processing unit. The control instruction unit is connected to the optical switch, the anti-coding switch unit, and the parallel-serial conversion unit, respectively; the low-noise high-gain optical amplifier is connected to the optical switch; the optical switch is connected to the first balanced detector and the second balanced detector by means of the filter, the optical delay interferometer I, and the optical delay interferometer Q, respectively. This system improves the compatibility of a communication system at a relay node in an existing laser communication network.

Abstract: A phase-lock-free system includes a control instruction unit, a low-noise high-gain optical amplifier, an optical switch, a filter, an optical delay interferometer I, an optical delay interferometer Q, a first balanced detector, a second balanced detector, an anti-coding switch unit, a parallel-serial conversion unit, and a data processing unit. The control instruction unit is connected to the optical switch, the anti-coding switch unit, and the parallel-serial conversion unit, respectively; the low-noise high-gain optical amplifier is connected to the optical switch; the optical switch is connected to the first balanced detector and the second balanced detector by means of the filter, the optical delay interferometer I, and the optical delay interferometer Q, respectively. This system improves the compatibility of a communication system at a relay node in an existing laser communication network.

Abstract: The disclosure relates to a multi-modulation-format compatible high-speed laser signal generation system and method. The disclosure can greatly improve modulation format compatibility of a laser communication system and saves system upgrading costs and resource costs. The system mainly includes a control instruction unit, a serial-parallel changeover switch unit, a precoding switch unit, a power control unit, an IQ modulator, a narrow line width laser, and a bias point control unit, wherein the control instruction unit is respectively connected to the serial-parallel changeover switch unit, the precoding switch unit, the power control unit, and the bias point control unit; the serial-parallel changeover switch unit, the precoding switch unit, the power control unit, and the IQ modulator are electrically connected in sequence; the narrow line width laser is connected to an optical input end of the IQ modulator; and the bias point control unit is connected to the IQ modulator.

Abstract: Disclosed herein is a vaccine comprising an antigen and IL-17. Also disclosed herein is a method for increasing an immune response in a subject. The method may comprise administering the vaccine to the subject in need thereof.

Abstract: Disclosed herein is a immunotherapeutic composition comprising IL-17. Also disclosed herein is a method of increasing an immune response in a subject in need thereof. The method may include administering the immunotherapeutic composition to the subject. The increased immune response may protect against an influenza virus. Further disclosed herein is a method of diagnosing influenza viral infection.

Abstract: The present invention relates to an adaptive and all-optical method for data packet rate multiplication compatible with multiple data rates and/or multiple communication protocols. By performing a real-time pulse width compression on an original electronic or optical packet from an end user or a network interface device, the method generates an optical packet having an identical rate with the original packet while the duration of each pulse being significantly reduced. Then, by eliminating any redundant idle time due to the pulse width compression, the method also shortens data period and thus makes the rate of packet multiplied. The present invention addresses the technical problem of limited data rate in EO/OE conversion as known in the prior art and solves fundamentally the interconnection and communication between networks or systems of different data rates and/or protocols.

Abstract: The present invention relates to an adaptive and all-optical method for data packet rate multiplication compatible with multiple data rates and/or multiple communication protocols. By performing a real-time pulse width compression on an original electronic or optical packet from an end user or a network interface device, the method generates an optical packet having an identical rate with the original packet while the duration of each pulse being significantly reduced. Then, by eliminating any redundant idle time due to the pulse width compression, the method also shortens data period and thus makes the rate of packet multiplied. The present invention addresses the technical problem of limited data rate in EO/OE conversion as known in the prior art and solves fundamentally the interconnection and communication between networks or systems of different data rates and/or protocols.