Abstract: A denoising optimization method for an AC traction motor by chamfering a stator tooth shoulder includes taking an angular vertex of the stator tooth shoulder as an end point, obtaining two points equidistantly along two sides of a stator tooth shoulder angle from the end point; and using the two points as tangent points D1 and D2 of the inscribed arc; making the inscribed arc of the tooth shoulder angle through the two tangent points D1 and D2, cutting off the tooth shoulder angle along the inscribed arc, and adjusting an oblique height HS1 of a stator tooth pole shoe. The invention obtains optimal values of a chamfering size and oblique height of a stator tooth slot pole shoe by adjusting the oblique height of the stator tooth pole shoe and adopting a particle swarm optimization algorithm.

Abstract: Disclosed herein is a method for the prevention, delay of progression or treatment of indolent or aggressive B-cell lymphomas in an individual in need thereof, comprising administering a Btk inhibitor (in particularly (S)-7-(1-actyloylpiperidin-4-yl)-2-(4-phenoxyphenyl)-4,5,6,7-tetrahydropyrazolo-[1,5-a]pyrimidine-3-carboxamide or a pharmaceutically acceptable salt thereof) in combination with an anti-PD-1 antibody. The potent and selective BTK inhibitor in combination with the anti-PD-1 antibody have a manageable toxicity profile in patients with indolent and aggressive lymphomas.

Abstract: A module structure and a display device are disclosed. The module structure includes a backlight sheet, a display screen, and a glass cover which are stacked, and further includes a light guide plate, LED lights, and a flexible circuit board disposed between the display screen and the glass cover, the LED lights are located on a side of the light guide plate facing away from a display area, and the LED lights are electrically connected to the flexible circuit board.

Abstract: In some embodiments, the present disclosure pertains to a method for capturing alkenes that includes: associating the alkenes with metal-organic frameworks, where the metal-organic frameworks includes one or more metals and one or more ligands coordinated with the one or more metals, and where the metal-organic frameworks are conductive; and oxidizing the metal-organic frameworks, where the oxidizing results in a capturing of the alkenes by the metal-organic frameworks. Additional embodiments of the present disclosure pertain to a system for capturing alkenes that includes: metal-organic frameworks, where the metal-organic frameworks include one or more metals and one or more ligands coordinated with the one or more metals, and where the metal-organic frameworks are conductive; and an alkene feed source associated with the metal-organic frameworks, where the alkene feed source is configured to deliver an alkene feed to the system.

Abstract: A scroll assembly includes an orbiting scroll and a cross ring. The orbiting scroll is configured to have a bottom plate. A plurality of bayonets and two positioning slots are provided on the outer peripheral surface of the bottom plate. The bayonets are adapted to be clamped by a chuck of a turning tool. The cross ring is configured to have an annular body and two positioning pins. An annular groove adapted for being formed by turning is provided on the lower surface of the bottom plate of the orbiting scroll, and a chamfer is formed on the edge of the annular groove formed by the intersection of the circumferential vertical surface of the positioning groove and the lower surface of the bottom plate.

Abstract: Provided are an antibody targeting Claudin 18.2, an antibody-drug conjugate, and use thereof in treatment of cancer. Also provided are a nucleotide encoding the Claudin 18.2 antibody, a polynucleotide combination, an expression vector, an expression vector combination, a pharmaceutical composition comprising the Caudill 18.2 antibody and the antibody-drug conjugate, and an application thereof in preparation of a medication for treatment or prevention of cancer.

Abstract: The present disclosure relates to a battery cell to alleviate the problem of impurities falling into an electrode assembly. Wherein, the battery cell includes: an electrode assembly including a tab and a cell body, wherein the tab is connected to the cell body; a cover plate assembly including an electrode terminal and a cover plate, wherein the electrode terminal is disposed on the cover plate; a connecting sheet connected between the tab and the electrode terminal, the connecting sheet includes a first connecting portion and a second connecting portion, wherein the first connecting portion is connected to the tab, and the second connecting portion is connected to the electrode terminal; an insulating pallet disposed between the cell body and the connecting sheet; and an insulation member disposed between the insulating pallet and the second connecting portion.

Abstract: The present disclosure relates to a battery cell to alleviate the problem of impurities falling into an electrode assembly. Wherein, the battery cell includes: an electrode assembly including a tab and a cell body, wherein the tab is connected to the cell body; a cover plate assembly including an electrode terminal and a cover plate, wherein the electrode terminal is disposed on the cover plate; a connecting sheet connected between the tab and the electrode terminal, the connecting sheet includes a first connecting portion and a second connecting portion, wherein the first connecting portion is connected to the tab, and the second connecting portion is connected to the electrode terminal; an insulating pallet disposed between the cell body and the connecting sheet; and an insulation member disposed between the insulating pallet and the second connecting portion.

Abstract: Provided are methods related to treating congenital adrenal hyperplasia in a subject in need thereof comprising administering to the subject a compound of Formula (I): [INSERT FORMULA] (I), or a pharmaceutically acceptable salt thereof.

Abstract: The present application concerns methods for treating an IL-6-mediated disorder such as rheumatoid arthritis (RA), juvenile idiopathic arthritis (JIA), systemic JIA (sJIA), polyarticular course JIA (pcJIA), systemic sclerosis, or giant cell arteritis (GCA), with subcutaneously administered antibody that binds interleukin-6 receptor (anti-IL-6R antibody). In particular, it relates to identification of a fixed dose of anti-IL-6R antibody, e.g. tocilizumab, which is safe and effective for subcutaneous administration in patients with IL-6-mediated disorders. In addition, formulations and devices useful for subcutaneous administration of an anti-IL-6R antibody are disclosed.

Abstract: The present disclosure relates to a battery cell to alleviate the problem of impurities falling into an electrode assembly. Wherein, the battery cell includes: an electrode assembly including a tab and a cell body, wherein the tab is connected to the cell body; a cover plate assembly including an electrode terminal and a cover plate, wherein the electrode terminal is disposed on the cover plate; a connecting sheet connected between the tab and the electrode terminal, the connecting sheet includes a first connecting portion and a second connecting portion, wherein the first connecting portion is connected to the tab, and the second connecting portion is connected to the electrode terminal; an insulating pallet disposed between the cell body and the connecting sheet; and an insulation member disposed between the insulating pallet and the second connecting portion.

Abstract: The present application concerns methods for treating an IL-6-mediated disorder such as rheumatoid arthritis (RA), juvenile idiopathic arthritis (JIA), systemic JIA (sJIA), polyarticular course JIA (pcJIA), systemic sclerosis, or giant cell arteritis (GCA), with subcutaneously administered antibody that binds interleukin-6 receptor (anti-IL-6R antibody). In particular, it relates to identification of a fixed dose of anti-IL-6R antibody, e.g. tocilizumab, which is safe and effective for subcutaneous administration in patients with IL-6-mediated disorders. In addition, formulations and devices useful for subcutaneous administration of an anti-IL-6R antibody are disclosed.

Abstract: A color matching method and a color matching device are provided, the color matching method includes: S1, determining a target color; S2, judging whether color data of a sample is obtained, if yes, proceeding to step S3, and if not, proceeding to step S5; S3, measuring the color data of the sample and displaying a color on a substrate, and proceeding to step S4; S4, judging whether the color displayed on the substrate is consistent with the target color, and if not, proceeding to step S6, and if yes, proceeding to step S7; S5, selecting a color and emitting light consistent with a chromaticity value of the selected color onto the substrate and proceeding to step S6; S6, adjusting the color displayed on the substrate until an adjusted color displayed on the substrate is consistent with the target color, and proceeding to S7; and S7, storing data.

Abstract: An end cover assembly for a battery cell includes an end cover provided with a through hole, a sealing member configured to seal the through hole and connected to the end cover to form a joint, and a barrier member provided at the through hole with a channel formed between at least part of the barrier member and a side wall of the through hole. The channel is configured to guide fluid in the battery cell to the joint.

Abstract: The present application concerns methods for treating an IL-6-mediated disorder such as rheumatoid arthritis (RA), juvenile idiopathic arthritis (JIA), systemic JIA (sJIA), polyarticular course JIA (pcJIA), systemic sclerosis, or giant cell arteritis (GCA), with subcutaneously administered antibody that binds interleukin-6 receptor (anti-IL-6R antibody). In particular, it relates to identification of a fixed dose of anti-IL-6R antibody, e.g. tocilizumab, which is safe and effective for subcutaneous administration in patients with IL-6-mediated disorders. In addition, formulations and devices useful for subcutaneous administration of an anti-IL-6R antibody are disclosed.

Abstract: Described is a pressure relief mechanism, a battery cell, a battery, an electric apparatus, and a manufacturing method thereof. A pressure relief mechanism is provided on a housing plate of a battery cell and includes: a connecting portion, where the connecting portion is located at an outer peripheral region of the pressure relief mechanism and is configured to connect the housing plate; a first part, where an end of the first part is connected to the connecting portion, and another end protrudes obliquely toward an interior of the battery cell; a weak portion, where the weak portion is provided at the protruding end of the first part; and a second part, where an outer edge region of the second part is connected to the weak portion, and the outer edge region extends obliquely away from the interior of the battery cell.

Abstract: A method for preparing a butyronitrile rubber powder-based polyvinyl chloride (PVC) thermoplastic elastomer and a use of the butyronitrile rubber powder-based PVC thermoplastic elastomer in preparing automotive parts are provided. The method includes: activating a wasted nitrile butadiene rubber (NBR) powder; plasticizing one of NBR and chloroprene rubber (CR) to obtain a plasticized rubber; dispersing the activated NBR fine rubber powder with one of PVC and chlorinated polyethylene (CPE) in a kneader evenly to obtain a mixture; adding the mixture and pine tar into the plasticized rubber, then mixing evenly to obtain a mixed plastic; adding various compounding agents into the mixed plastic and dispersing evenly to perform cross-linking reaction, thereby obtaining the butyronitrile rubber powder-based PVC thermoplastic elastomer.

Abstract: In some embodiments, the present disclosure pertains to a method for capturing alkenes that includes: associating the alkenes with metal-organic frameworks, where the metal-organic frameworks includes one or more metals and one or more ligands coordinated with the one or more metals, and where the metal-organic frameworks are conductive; and oxidizing the metal-organic frameworks, where the oxidizing results in a capturing of the alkenes by the metal-organic frameworks. Additional embodiments of the present disclosure pertain to a system for capturing alkenes that includes: metal-organic frameworks, where the metal-organic frameworks include one or more metals and one or more ligands coordinated with the one or more metals, and where the metal-organic frameworks are conductive; and an alkene feed source associated with the metal-organic frameworks, where the alkene feed source is configured to deliver an alkene feed to the system.

Abstract: A scroll assembly includes an orbiting scroll and a cross ring. The orbiting scroll is configured to have a bottom plate. A plurality of bayonets and two positioning slots are provided on the outer peripheral surface of the bottom plate. The bayonets are adapted to be clamped by a chuck of a turning tool. The two positioning slots are arranged centrally symmetrically relative to the center of the orbiting scroll. Each of the positioning slots comprises two radial vertical surfaces, a circumferential vertical surface and an opening facing outwards in the radial direction. The cross ring is configured to have an annular body and two positioning pins.

Abstract: A method for driving display panel includes: for one of adjacent two frames of displayed images, when scanning odd-numbered row of sub-pixels, inputting data signals to the data lines coupled to the data selector in first order by a data selector; when scanning even-numbered row of sub-pixels, inputting data signals to the data lines coupled to the data selector in second order by the data selector; first and second orders each represents an order of inputting data signals to the data lines; first order is opposite to second order; for the other of the adjacent two frames of displayed images, when scanning odd-numbered row of sub-pixels, inputting data signals to the data lines coupled to the data selector in second order by the data selector; when scanning even-numbered row of sub-pixels, inputting data signals to the data lines coupled to the data selector in first order by the data selector.