Abstract: Disclosed are a compound as an inhibitor of complement factor D, and a pharmaceutical composition thereof and the use thereof. Specifically disclosed are a compound as represented by formula (I), a tautomer thereof, a stereoisomer thereof and a prodrug thereof, or a pharmaceutically acceptable salt of any one of the above-mentioned compounds, or a solvate of any one of the above-mentioned compounds. The compound has a good inhibitory activity on complement factor D, and has an excellent pharmacokinetic and pharmacodynamic activity.

Abstract: A quick tripping device of a circuit breaker having a contact system that includes a moving contact mechanism and a static contact, wherein the moving contact mechanism includes a contact support and a moving contact, and a contact spring having, two ends connected with the moving contact and the contact support respectively. The quick tripping device further includes a first transmission structure in driving fit with the contact spring and rotatable rotates along with the contact spring. When a short-circuiting current flows through the contact system, the moving contact is repelled by an electric repulsive force between the moving contact and the static contact, so that the moving contact rotates relative to the contact support. The moving contact drives the first transmission structure to rotate through the contact spring, and the first transmission structure drives an operating mechanism to trip.