Patents by Inventor Xiaorui Yao

Xiaorui Yao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NRIP1 regulation of apolipoprotein A1
    Patent number: 8257921
    Abstract: The present invention provides, in part, methods for identifying inhibitors of NRIP1 and methods of using such inhibitors. Methods of treating NRIP1-mediated disorders using NRIP1 inhibitor are also provided.
    Type: Grant
    Filed: December 22, 2009
    Date of Patent: September 4, 2012
    Assignee: Schering Corporation
    Inventors: Xiaorui Yao, Scott W. Altmann, Liji Zhu
  • NPC1L1 orthologues
    Patent number: 8212016
    Abstract: The present invention provides, in part, NPC1L1 from various species. Methods of using the NPC1L1 polypeptides and polynucleotide set forth herein, e.g., in screening assays, are also set forth.
    Type: Grant
    Filed: February 14, 2011
    Date of Patent: July 3, 2012
    Assignee: Schering Corporation
    Inventors: Scott W. Altmann, Xiaorui Yao, Kim Anne O'Neill, Brian E. Hawes
  • NPC1L1 ORTHOLOGUES
    Publication number: 20120084871
    Abstract: The present invention provides, in part, NPC1L1 from various species. Methods of using the NPC1L1 polypeptides and polynucleotide set forth herein, e.g., in screening assays, are also set forth.
    Type: Application
    Filed: February 14, 2011
    Publication date: April 5, 2012
    Applicant: Schering Corporation
    Inventors: Scott Altmann, Xiaorui Yao, Kim Anne O'Neill, Brian E. Hawes
  • NPC1L1 orthologues
    Patent number: 7910698
    Abstract: The present invention provides, in part, NPC1L1 from various species. Methods of using the NPC1L1 polypeptides and polynucleotide set forth herein, e.g., in screening assays, are also set forth.
    Type: Grant
    Filed: February 22, 2007
    Date of Patent: March 22, 2011
    Assignee: Schering Corporation
    Inventors: Scott Altmann, Xiaorui Yao, Kim Ann O'Neill, Brian E. Hawes
  • Use of azetidinone compounds
    Patent number: 7723020
    Abstract: The use of azetidinone compounds that are inhibitors of cholesterol absorption as tools for discovering and characterizing proteins involved in trafficking or absorption of cholesterol and/or cholesteryl esters in biological systems is presented. These compounds can serve as tools for competitive binding assays to discover and characterize other chemical agents useful as cholesterol absorption inhibitors. New compounds of the present invention are also highly efficacious inhibitors of cholesterol absorption.
    Type: Grant
    Filed: October 25, 2006
    Date of Patent: May 25, 2010
    Assignee: Schering Corporation
    Inventors: Scott W. Altmann, Duane A. Burnett, Harry R. Davis, Jr., Michael P. Graziano, Maureen Laverty, Xiaorui Yao
  • NPC1L1 orthologues
    Publication number: 20090098128
    Abstract: The present invention provides, in part, NPC1L1 from various species. Methods of using the NPC1L1 polypeptides and polynucleotide set forth herein, e.g., in screening assays, are also set forth.
    Type: Application
    Filed: February 22, 2007
    Publication date: April 16, 2009
    Inventors: Scott W. Altmann, Xiaorui Yao, Kim Ann O'Neill, Brian E. Hawes
  • Use of azetidinone compounds
    Publication number: 20070105141
    Abstract: The use of azetidinone compounds that are inhibitors of cholesterol absorption as tools for discovering and characterizing proteins involved in trafficking or absorption of cholesterol and/or cholesteryl esters in biological systems is presented These compounds can serve as tools for competitive binding assays to discover and characterize other chemical agents useful as cholesterol absorption inhibitors. New compounds of the present invention are also highly efficacious inhibitors of cholesterol absorption.
    Type: Application
    Filed: October 25, 2006
    Publication date: May 10, 2007
    Applicant: Schering Corporation
    Inventors: Scott Altmann, Duane Burnett, Harry Davis, Michael Graziano, Maureen Laverty, Xiaorui Yao
  • Use of azetidinone compounds
    Patent number: 7144696
    Abstract: The use of azetidinone compounds that are inhibitors of cholesterol absorption as tools for discovering and characterizing proteins involved in trafficking or absorption of cholesterol and/or cholesteryl esters in biological systems is presented. These compounds can serve as tools for competitive binding assays to discover and characterize other chemical agents useful as cholesterol absorption inhibitors. New compounds of the present invention are also highly efficacious inhibitors of cholesterol absorption.
    Type: Grant
    Filed: May 6, 2005
    Date of Patent: December 5, 2006
    Assignee: Schering Corporation
    Inventors: Scott W. Altmann, Duane A. Burnett, Harry R. Davis, Jr., Michael P. Graziano, Maureen Laverty, Xiaorui Yao
  • Use of azetidinone compounds
    Publication number: 20050208568
    Abstract: The use of azetidinone compounds that are inhibitors of cholesterol absorption as tools for discovering and characterizing proteins involved in trafficking or absorption of cholesterol and/or cholesteryl esters in biological systems is presented. These compounds can serve as tools for competitive binding assays to discover and characterize other chemical agents useful as cholesterol absorption inhibitors. New compounds of the present invention are also highly efficacious inhibitors of cholesterol absorption.
    Type: Application
    Filed: May 6, 2005
    Publication date: September 22, 2005
    Inventors: Scott Altmann, Duane Burnett, Harry Davis, Michael Graziano, Maureen Laverty, Xiaorui Yao
  • Use of azetidinone compounds
    Patent number: 6933107
    Abstract: The use of azetidinone compounds that are inhibitors of cholesterol absorption as tools for discovering and characterizing proteins involved in trafficking or absorption of cholesterol and/or cholesteryl esters in biological systems is presented. These compounds can serve as tools for competitive binding assays to discover and characterize other chemical agents useful as cholesterol absorption inhibitors. New compounds of the present invention are also highly efficacious inhibitors of cholesterol absorption.
    Type: Grant
    Filed: May 15, 2003
    Date of Patent: August 23, 2005
    Assignee: Schering Corporation
    Inventors: Scott W. Altmann, Duane A. Burnett, Harry R. Davis, Jr., Michael P. Graziano, Maureen Laverty, Xiaorui Yao
  • Use of azetidinone compounds
    Publication number: 20030215869
    Abstract: The use of azetidinone compounds that are inhibitors of cholesterol absorption as tools for discovering and characterizing proteins involved in trafficking or absorption of cholesterol and/or cholesteryl esters in biological systems is presented. These compounds can serve as tools for competitive binding assays to discover and characterize other chemical agents useful as cholesterol absorption inhibitors. New compounds of the present invention are also highly efficacious inhibitors of cholesterol absorption.
    Type: Application
    Filed: May 15, 2003
    Publication date: November 20, 2003
    Inventors: Scott W. Altmann, Duane A. Burnett, Harry R. Davis, Michael P. Graziano, Maureen Laverty, Xiaorui Yao
  • Use of azetidinone compounds
    Patent number: 6632933
    Abstract: The use of azetidinone compounds that are inhibitors of cholesterol absorption as tools for discovering and characterizing proteins involved in trafficking or absorption of cholesterol and/or cholesteryl esters in biological systems is presented. These compounds can serve as tools for competitive binding assays to discover and characterize other chemical agents useful as cholesterol absorption inhibitors. New compounds of the present invention are also highly efficacious inhibitors of cholesterol absorption.
    Type: Grant
    Filed: July 30, 2001
    Date of Patent: October 14, 2003
    Assignee: Schering Corporation
    Inventors: Scott W. Altmann, Duane A. Burnett, Harry R. Davis, Jr., Michael P. Graziano, Maureen Laverty, Xiaorui Yao
  • Use of azetidinone compounds
    Patent number: 6593078
    Abstract: The use of azetidinone compounds that are inhibitors of cholesterol absorption as tools for discovering and characterizing proteins involved in trafficking or absorption of cholesterol and/or cholesteryl esters in biological systems is presented. These compounds can serve as tools for competitive binding assays to discover and characterize other chemical agents useful as cholesterol absorption inhibitors. New compounds of the present invention are also highly efficacious inhibitors of cholesterol absorption.
    Type: Grant
    Filed: April 12, 2000
    Date of Patent: July 15, 2003
    Assignee: Schering Corporation
    Inventors: Scott W. Altmann, Duane A. Burnett, Harry R. Davis, Jr., Michael P. Graziano, Maureen Laverty, Xiaorui Yao
  • Use of azetidinone compounds
    Publication number: 20020009714
    Abstract: The use of azetidinone compounds that are inhibitors of cholesterol absorption as tools for discovering and characterizing proteins involved in trafficking or absorption of cholesterol and/or cholesteryl esters in biological systems is presented. These compounds can serve as tools for competitive binding assays to discover and characterize other chemical agents useful as cholesterol absorption inhibitors. New compounds of the present invention are also highly efficacious inhibitors of cholesterol absorption.
    Type: Application
    Filed: July 30, 2001
    Publication date: January 24, 2002
    Inventors: Scott W. Altmann, Duane A. Burnett, Harry R. Davis, Michael P. Graziano, Maureen Laverty, Xiaorui Yao