Abstract: A computer implemented method for self-learning of a control system. The method includes creating an initial knowledge base. The method learns first principles using the knowledge base. The method creates initial control commands derived from the knowledge base. The method generates constraints for the control commands. The method performs constrained reinforcement learning by executing the control commands with the constraints and observing feedback to improve the control commands. The method enriches the knowledge base based on the feedback.

Abstract: A computer-implemented method of answering questions comprises: receiving, by one or more processors, a query; based on the query, generating, by the one or more processors, a matrix; based on the matrix, modifying, by the one or more processors, a dynamic memory; based on the matrix, determining, by the one or more processors, a first response from the dynamic memory; based on the matrix, determining, by the one or more processors, a second response from a database; based on the first response and the second response, determining, by the one or more processors, a third response; and in response to the query, providing, by the one or more processors, the third response.

Abstract: An embodiment of the application provides a method for representing internet of vehicles (IOV) knowledge based on a simplicial complex (SC). The method includes: representing k?-dimensional knowledge in a k-dimensional continuous space by using a k-dimensional SC with k?-dimensional function values; and representing a safe boundary of the IOV knowledge by using a boundary of the SC, where the IOV knowledge includes a steering wheel angle of an ego-vehicle, a road curvature, a speed of the ego-vehicle, and an inter-parameter relationship compliant with an objective law of vehicle dynamics, where the steering wheel angle of the ego-vehicle, the road curvature, and the speed of the ego-vehicle are obtained by using a sensor on the ego-vehicle.

Abstract: Methods, apparatus, and systems are provided for integrated driver expression recognition and vehicle interior environment classification to detect driver condition for safety. A method includes obtaining an image of a driver of a vehicle and an image of an interior environment of the vehicle. Using a machine learning method, the images are processed to classify a condition of the driver and of the interior environment of the vehicle. The machine learning method includes general convolutional neural network (CNN) and CNN with adaptive filters. The adaptive filters are determined based on influence of filters. The classification results are combined and compared with predetermined thresholds to determine if a decision can be made based on existing information. Additional information is requested by self-motivated learning if a decision cannot be made, and safety is determined based on the combined classification results. A warning is provided to the driver based on the safety determination.

Abstract: Various embodiments include systems and methods structured to provide recognition of an object in an image using a learning module trained using decomposition of the object into components in a number of training images. The training can be based on an overall objectness score of the object, an objectness score of each component of the object, a pose of the object, and a pose of each component of the object for each training image input. Additional systems and methods can be implemented in a variety of applications.

Abstract: Methods, apparatus, and systems are provided for integrated driver expression recognition and vehicle interior environment classification to detect driver condition for safety. A method includes obtaining an image of a driver of a vehicle and an image of an interior environment of the vehicle. Using a machine learning method, the images are processed to classify a condition of the driver and of the interior environment of the vehicle. The machine learning method includes general convolutional neural network (CNN) and CNN with adaptive filters. The adaptive filters are determined based on influence of filters. The classification results are combined and compared with predetermined thresholds to determine if a decision can be made based on existing information. Additional information is requested by self-motivated learning if a decision cannot be made, and safety is determined based on the combined classification results. A warning is provided to the driver based on the safety determination.

Abstract: Various embodiments include systems and methods structured to provide recognition of an object in an image using a learning module trained using decomposition of the object into components in a number of training images. The training can be based on an overall objectness score of the object, an objectness score of each component of the object, a pose of the object, and a pose of each component of the object for each training image input. Additional systems and methods can be implemented in a variety of applications.

Abstract: A computer-implemented method of answering questions comprises: receiving, by one or more processors, a query; based on the query, generating, by the one or more processors, a matrix; based on the matrix, modifying, by the one or more processors, a dynamic memory; based on the matrix, determining, by the one or more processors, a first response from the dynamic memory; based on the matrix, determining, by the one or more processors, a second response from a database; based on the first response and the second response, determining, by the one or more processors, a third response; and in response to the query, providing, by the one or more processors, the third response.

Abstract: A computer-implemented method of controlling an autonomous system comprises: accessing, by one or more processors, sensor data that includes information regarding an area; disregarding, by the one or more processors, a portion of the sensor data that corresponds to objects outside of a region of interest; identifying, by the one or more processors, a plurality of objects from the sensor data; assigning, by the one or more processors, a priority to each of the plurality of objects; based on the priorities of the objects, selecting, by the one or more processors, a subset of the plurality of objects; generating, by the one or more processors, a representation of the selected objects; providing, by the one or more processors, the representation to a machine learning system as an input; and based on an output from the machine learning system resulting from the input, controlling the autonomous system.

Abstract: Disclosed are salts and crystalline forms of N-(4-(2-amino-3-chloropyridin-4-yloxy)-3-fluorophenyl)-4-ethoxy-1-(4-fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide and salts thereof. Also disclosed are at least one pharmaceutical composition comprising at least one crystalline form of N-(4-(2-amino-3-chloropyridin-4-yloxy)-3-fluorophenyl)-4-ethoxy-1-(4-fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide, at least one method of using at least one crystalline form of N-(4-(2-amino-3-chloropyridin-4-yloxy)-3-fluorophenyl)-4-ethoxy-1-(4-fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide to treat cancer and/or other proliferative diseases, and processes to prepare crystalline forms of N-(4-(2-amino-3-chloropyridin-4-yloxy)-3-fluorophenyl)-4-ethoxy-1-(4-fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide and salts thereof.

Abstract: The instant invention provides crystalline forms of 1-(3-chlorophenyl)-7-oxo-6-[4-(2-oxo-1 (2H)pyridinyl)phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide and its solvates thereof; processes for the production of such crystalline forms; pharmaceutical compositions comprising such crystalline forms; and methods of treating thromboembolic disorders with such crystalline forms or such pharmaceutical compositions.

Abstract: A laboratory sample plate for use in PXRD and other testing techniques includes a quartz body having substantially planar top and bottom surfaces that are parallel with each other. The quartz body includes a matrix of cylindrical apertures that are substantially perpendicular to the top and bottom surfaces. Each aperture has an upper opening at the top surface and a lower opening at the bottom surface of the plate body. A synthetic quartz bottom sheet is fused to the bottom surface of the quartz body. The quartz bottom sheet include respective portions that close the lower opening of each aperture in the quartz body, such that each aperture and respective portion of the bottom sheet together form a well for receiving a sample. Each aperture and respective portion of the bottom sheet are suitably dimensioned to perform a powder X-ray diffraction technique as well as microscopy and Raman spectroscopy on a sample contained in the well.

Abstract: A process is provided for preparing novel crystalline forms, namely selectively and consistently preparing the H2-1 dihydrate crystalline form, the H2-2 dihydrate crystalline form, the N-3 anhydrate crystalline form and the MTBE solvate crystalline form of the IKur compound (2S)-1-[[(7R)-7-(3,4-dichlorophenyl)-4,7-dihydro-5-methylpyrazolo[1,5]pyrimidine-6-yl]carbonyl]-2-(4-fluorophenyl)pyrrolidine. The process includes preparation of the H2-1 and H2-2 forms which are used in preparing the N-3 anhydrate form which is particularly stable and has suitable flow properties and desired particle size. Novel H2-1 dihydrate and H2-2 dihydrate forms, the N-3 anhydrate form and the MTBE solvate form of the above IKur compound, pharmaceutical compositions containing such novel forms and a method for preventing or treating arrhythmias including atrial fibrillation and IKur related conditions employing such novel forms are also provided.

Abstract: The instant invention provides crystalline forms of 1-(3-chlorophenyl)-7-oxo-6-[4-(2-oxo-1 (2H)pyridinyl)phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide and its solvates thereof; processes for the production of such crystalline forms; pharmaceutical compositions comprising such crystalline forms; and methods of treating thromboembolic disorders with such crystalline forms or such pharmaceutical compositions.