Abstract: Disclosed is a data fabric service system that can be implemented in a distributed computer network, such as a data intake and query system. The data index and query system can receive a search query and define a search scheme for applying the search query on distributed data storage systems including internal data storage and external data storage. The data index and query system may provide a portion of the search scheme to a search service of the data fabric service system, which can cause worker nodes of the data fabric service system to perform various functions—including applying the search query to the external data storage based on the portion of the search scheme in order to obtain search results.

Abstract: A glass rear cover includes a light-transmitting region. The light-transmitting region at least partially overlaps with a camera assembly in a thickness direction of the glass rear cover. The light-transmitting region allows light out of the glass rear cover to pass through the light-transmitting region to enter the camera assembly. The glass rear cover includes a first predetermined region and a second predetermined region. The first predetermined region is configured close to the light-transmitting region, and a strength of the first predetermined region is less than a strength of the second predetermined region. Therefore, when the glass rear cover is stressed, an extension direction of the crack on the glass rear cover is turned at the first predetermined region without reaching the light-transmitting region, avoiding the impact on image capturing of the camera assembly.

Abstract: The present invention provides a method of treating or preventing an inflammatory neurological disease in a subject, the method comprising administering to the subject a protein comprising an extracellular domain of CD39. The present invention also relates to binding proteins comprising an extracellular domain of CD39.

Abstract: Disclosed is a data fabric service system that can be implemented in a distributed computer network, such as a data intake and query system. The data index and query system can receive a search query and define a search scheme for applying the search query on distributed data storage systems including internal data storage and external data storage. The data index and query system may provide a portion of the search scheme to a search service of the data fabric service system, which can cause worker nodes of the data fabric service system to perform various functions—including applying the search query to the external data storage based on the portion of the search scheme in order to obtain search results.

Abstract: A suspended moxibustion device including a mounting base, a suspended moxibustion head, a motor, a link lever and a crank. The mounting base includes a first and second mounting positions. The suspended moxibustion head includes a suspended moxibustion body with a mounting piece for mounting a moxa stick and is rotatably connected to the first mounting position. The motor is connected to one end of the suspended moxibustion head away from the suspended moxibustion body, and an output shaft of the motor is parallel to a rotating axis of the suspended moxibustion head. One end of the link lever away from the motor is rotatably connected to the second mounting position. The crank is perpendicular to the output shaft, one end of the crank is connected with the output shaft, and another end of the crank is rotationally connected to one end of the link lever close to the motor.

Abstract: The present disclosure discloses an active camera relocation method having robustness to illumination includes the following steps: extracting effective plane region image sets of scenes in a current observation image T and a reference observation image R; establishing a matching relationship in the effective plane region image sets T and R; obtaining a camera relative pose Pi guided by each group of matched planes; obtaining information for guiding the motion of a camera by fusing all camera relative poses Pi; determining whether a relocation process is completed by motion steps.

Abstract: The disclosed implementations include a method performed by a data intake and query system. The method includes receiving a search query at a search head, the search query including a branching operation between sets of data, generating a first subquery and a second subquery corresponding to the sets of data for execution by a search node, generating instructions for an intermediary node to combine partial results of the first subquery and the second subquery and instructions to concurrently communicate the subqueries to a search node, and executing the query by providing the instructions for the intermediary node to the intermediary node and the subqueries to the search node, the intermediary node receiving sets of partial search results for the subqueries, performing at least a portion of the branching operation on the partial results, and communicating the combined results to another intermediary node or the search head.

Abstract: The present disclosure discloses a fluorine-containing resin composition, including the following as raw materials, in parts by weight: a alkali-soluble resin (A) containing a compound (I), a photoinitiator, a sensitizer, a reactive diluent, a solvent and an assistant; the structural formula of the monomer of the compound (I) is shown as follows: wherein R is selected from the group consisting of —CH?CH2, —C(CH3)?CH2, acryloyl and methacryloyl; R1, R1?, R2, and R2? are each independently selected from the group consisting of hydrogen, hydroxyl, C1-C4 alkyl and C1-C4 alkoxy; R3 is selected from the group consisting of hydrogen and C1-C6 alkyl; the A ring is selected from the group consisting of cyclohexyl and phenyl; and the B ring is selected from the group consisting of phenyl, naphthyl and anthryl.

Abstract: The disclosed embodiments include a method performed by a data intake and query system. The method includes receiving a search query by a search head, defining a search process for applying the search query to indexers, delegating a first portion of the search process to indexers and a second portion of the search process to intermediary node(s) communicatively coupled to the search head and the indexers. The first portion can define a search scope for obtaining partial search results of the indexers and the second portion can define operations for combining the partial search results by the intermediary node(s) to produce a combination of the partial search results. The search head then receives the combination of the partial search results, and outputs final search results for the search query, where the final search results are based on the combination of the partial search results.

Abstract: Systems and methods are disclosed for mapping search nodes to a search head in a data intake and query system based on a tenant identifier in order to execute a query received by the data intake and query system. The mapping may allow same or similar search nodes to be used to execute queries that are associated with a particular tenant identifier, in order to take advantage of caching and local data stored with those search nodes. In some cases, search nodes can be mapped based on the tenant identifier using a hashing algorithm, such as a consistent hashing algorithm.

Abstract: The present disclosure provides methods of reducing, minimizing, or inhibiting the formation of double-stranded ribonucleic acid (dsRNA) during the preparation of ribonucleic acid (RNA), such as messenger ribonucleic acid (mRNA), by adding at least one chaotropic agent to a starting reaction mixture. The present disclosure provides methods of reducing, minimizing, or inhibiting intramolecular base-pairing within a ribonucleic acid (RNA) transcript and/or intermolecular base-pairing between an RNA transcript and deoxyribonucleic acid (DNA) or another RNA during the preparation of ribonucleic acid (RNA), by adding at least one chaotropic agent to a starting reaction mixture.

Abstract: Provided are systems and methods for concurrent summarization of indexed data. In some embodiments, two or more summary processes can be executed concurrently (e.g., in parallel) by an indexer to generate summaries for respective subsets of indexed data (e.g., partitions or buckets of indexed data) managed by the indexer.

Abstract: The present invention falls within the field of medical chemistry and relates to a class of compounds as SHP2 inhibitors and the use thereof. Specifically, the present invention provides a compound represented by formula (I), or an isomer, a pharmaceutically acceptable salt, a solvate, a crystal or a prodrug thereof, a preparation method therefor, a pharmaceutical composition comprising the compounds, and the use of the compounds or the composition for treating a disease mediated by SHP2.

Abstract: The present disclosure belongs to the technical field of smart homes, and particularly relates to a detergent recommendation method and equipment. The detergent recommendation method of the present disclosure includes: obtaining usage numbers respectively corresponding to various types of washing programs used by a user where the various types of washing programs respectively correspond to different types of detergents, selecting N types of washing programs with a maximum usage number from various types of washing programs according to the usage numbers, and pushing a prompt information of detergents respectively corresponding to the N types of the washing programs to the user, and can preferentially recommend the detergent suitable for the washing program with higher operating frequency to the user based on the usage number of the user using different washing programs.

Abstract: Disclosed is a data fabric service system that can be implemented in a distributed computer network, such as a data intake and query system. The data index and query system can receive a search query and define a search scheme for applying the search query on distributed data storage systems including internal data storage and external data storage. The data index and query system may provide a portion of the search scheme to a search service of the data fabric service system, which can cause worker nodes of the data fabric service system to perform various functions—including applying the search query to the external data storage based on the portion of the search scheme in order to obtain search results.

Abstract: Systems and methods are disclosed for mapping search nodes to a search head in a data intake and query system based on a tenant identifier in order to execute a query received by the data intake and query system. The mapping may allow same or similar search nodes to be used to execute queries that are associated with a particular tenant identifier, in order to take advantage of caching and local data stored with those search nodes. In some cases, search nodes can be mapped based on the tenant identifier using a hashing algorithm, such as a consistent hashing algorithm.

Abstract: The present disclosure provides a method for identifying a human growth hormone proteoform (hGHP) pattern biomarker. The method includes: collecting an hGH-secreting pituitary adenoma tissue sample and a normal pituitary tissue sample, and extracting tissue proteins, separately; conducting two-dimensional gel electrophoresis (2DGE), western blotting, and Coomassie brilliant blue (CBB) staining, and scanning visualized polyvinylidene fluoride (PVDF) membranes and 2D gels to obtain digital images; subjecting a corresponding protein in 2D gel spot to protein digestion with trypsin and purification, and conducting mass spectrometry identification and bioinformatics analysis to identify a GHP biomarker profile; and in combination with bioinformatics, using quantitative phosphoproteomics, quantitative ubiquitinomics, and quantitative acetylomics to identify post-translational modifications (PTMs) and splicing variations in GHP.

Abstract: An ester polymer has a structure represented by the following formula (I): T represents the backbone of the ester polymer; the group B is each independently selected from O or S; the group R each independently represents C1-10 hydrocarbylene group; the group A is each independently selected from O, S or NR?; the group R? each independently represents C1-10 hydrocarbylene group; the group Nb is each independently selected from H or —R??—B?H, wherein at least one of the two Nb on the same nitrogen atom is —R??—B?H; the group R? is each independently selected from H or C1-10 hydrocarbyl group; the group R?? each independently represents C1-10 hydrocarbylene group; the group B? is each independently selected from O or S; each y independently represents an integer between 1 and 6; and m is an integer between 1 and 10.