Abstract: Provided in the present disclosure is a compound of formula (I), or an N-oxide, solvate, pharmaceutically acceptable salt or stereoisomer thereof, which is an extrahepatic targeted cationic lipid compound with high efficiency and low toxicity. Further provided are a composition containing the aforementioned compound, and the use thereof in the delivery of a therapeutic or prophylactic agent.

Abstract: An optical computing topology structure configured to implement large-scale adjustment of a topology structure for different application scenarios. The optical computing topology structure includes a first physical medium, a spatial light modulator, and a second physical medium. The first physical medium, the spatial light modulator, and the second physical medium are sequentially connected. The first physical medium is configured to mix an input optical field, to implement a fully connected topology of the input optical field, to obtain a to-be-modulated optical field. The spatial light modulator is configured to modulate an optical field parameter of the to-be-modulated optical field to obtain a to-be-output optical field. The second physical medium is configured to mix the to-be-output optical field, to implement a fully connected topology of the to-be-output optical field, to obtain an output optical field.

Abstract: This application provides a dynamic scene processing method and apparatus, and a neural network model training method and apparatus, and relates to the field of artificial intelligence. The method includes: obtaining time domain spectral data X(?, x, y) of a dynamic scene, where ? indicates a frequency domain dimension of the dynamic scene along a time direction, and x and y indicate spatial dimensions of the dynamic scene; and using the time domain spectral data as an input of a neural network model, to obtain a processing result of the dynamic scene. In this application, precision of the processing result of the dynamic scene can be improved.

Abstract: An optical computing device includes a control system, a light field modulation system, an optical computing system, and a light field detection system. The control system converts input data into complex amplitude-light field mapping information that is information representing an amplitude and/or a phase. The light field modulation system represents the input data based on an optical signal that is output based on the complex amplitude-light field mapping information obtained in the conversion procedure. A first computing result is generated based on the optical signal that represents the input data with high precision to complete optical computing.

Abstract: An optical computing device and a computing method are provided for an optical Ising machine with high operation efficiency. The optical computing device includes a first spin array, an optical feedback network, and a second spin array, where the optical feedback network is separately connected to the first spin array and the second spin array. The first spin array may receive a first group of signals including N optical pulses or N electrical signals, and generate a first group of spin signals including N spin signals. The optical feedback network may receive the first group of spin signals, and generate, based on the first group of spin signals and specified first data, a first group of feedback signals including N feedback signals. The first spin array and the second spin array may process a plurality of signals in parallel, to improve computation efficiency of the optical computing device.

Abstract: This application provides an optical chip. The optical chip includes an optical substrate, and a first functional layer, a first space layer, and a second functional layer that are sequentially disposed on the optical substrate. A second optical structure is formed at the second functional layer. The second optical structure includes a second inter-layer coupling structure and a second intra-layer transmission structure, and the second intra-layer transmission structure is located in a first area of the second functional layer. A first optical structure located in a second area is formed at the first functional layer. The first optical structure includes a first inter-layer coupling structure and a first intra-layer transmission structure, and a projection of the second area in a normal direction of a plane of the optical substrate does not overlap with a projection of the first area in the normal direction of the plane of the optical substrate.

Abstract: The present disclosure provides a method for separating a neural crest derived cell from peripheral blood. In the present disclosure, a mononuclear cell is separated from the peripheral blood and then directly cultured, thereby maximizing use of a neural crest stem cell with a differentiation potential to avoid loss of the neural crest stem cell. In the method of the present disclosure, a sample to be separated is derived from the peripheral blood. The method shows less trauma and low cost. Most importantly, compared to extracting the neural crest derived cell from tissues, the neural crest derived cell extracted from the peripheral blood can be used clinically as a type of biomarker.

Abstract: An optical computing apparatus includes a light source array, a modulator array, and a wavelength router. The light source array is configured to send a plurality of groups of optical signals based on first data to be computed. The modulator array includes a plurality of modulators. The modulator array is configured to receive the groups of optical signals, modulate the groups to provide modulated second data, and output a plurality of intermediate optical signals based on the modulated second data. The wavelength router is configured to receive the plurality of intermediate optical signals from the modulator array, and output, based on wavelengths of the intermediate optical signals, the intermediate optical signals as a plurality of second optical signals to a plurality of output ports to indicate a computing result of the first data and the second data.

Abstract: A signal folding device receives an input signal, and performs frequency modulation on a plurality of first analog signals based on the input signal to obtain a plurality of modulated first analog signals, where a frequency difference between two adjacent first analog signals in the plurality of modulated first analog signals is the same. The signal folding device may filter the plurality of modulated first analog signals based on a specified bandwidth to obtain a second analog signal, and demodulate the second analog signal to obtain an output signal. The output signal is a folded signal of the input signal within a target amplitude, and the second analog signal is an analog signal within the bandwidth.

Abstract: An optical computing apparatus and system and a computing method are provided. The optical computing apparatus includes a linear operation module, a first delay module, and a coupler. The linear operation module can modulate, based on received electrical signals, optical signals input to the linear operation module; the first delay module may adjust a delay of optical signals output by the linear operation module; and after the first delay module adjusts the delay of the optical signals output by the linear operation module, the coupler may combine a plurality of groups of optical signals successively output by the linear operation module, to output one group of optical signals used to indicate a computing result that is obtained after a multiply-add operation is performed on one group of data and weights.

Abstract: An optical computing device including a parametric oscillator array, an interaction computing matrix, a first feedback module connected to two ends of the parametric oscillator array, and a second feedback module connected to the parametric oscillator array and the interaction computing array. The parametric oscillator array is configured to receive a first group of signals, and generate a first group of optical signals including a plurality of first optical signals. The interaction computing array is configured to receive the first group of optical signals, and perform matrix operation on the first group of optical signals. The first feedback module is configured to receive the first group of optical signals, and transmit the first group of optical signals to the parametric oscillator array. The second feedback module is configured to receive the second group of optical signals, and transmit the second group of optical signals to the parametric oscillator array.

Abstract: A gene alignment technology may be applied to a computer system including an optical computing chip. In a process of performing gene alignment, a first group of gene fragments may be first obtained from a gene database based on a to-be-tested gene sequence, where the first group of gene fragments includes a plurality of reference gene fragments that match some bases of the to-be-tested gene sequence. After the first group of gene fragments is obtained, the to-be-tested gene sequence and the plurality of reference gene fragments in the first group of gene fragments may be input into the optical computing chip to perform optical alignment.

Abstract: An optical computing device and a computing method are provided, to provide an optical Ising machine with high operation efficiency. The optical computing device includes a first spin array, an optical feedback network, and a second spin array, where the optical feedback network is separately connected to the first spin array and the second spin array. The first spin array may receive a first group of signals including N optical pulses or N electrical signals, and generate a first group of spin signals including N spin signals. The optical feedback network may receive the first group of spin signals, and generate, based on the first group of spin signals and specified first data, a first group of feedback signals including N feedback signals. The first spin array and the second spin array may process a plurality of signals in parallel, to improve computation efficiency of the optical computing device.

Abstract: An optical computing chip includes a light source array, a first concave mirror, and a modulator array. The light source array is located on an objective focal plane of the first concave mirror. The modulator array is located on an image focal plane of the first concave mirror. The light source array generates a first optical signal based on first data. The first concave mirror outputs a first reflected optical signal based on the first optical signal. The modulator array receives the first reflected optical signal, obtains first spectrum plane distribution data based on the first reflected optical signal, and modulates the first spectrum plane distribution data onto the modulator array.

Abstract: The present application relates to metal cutting, and more particularly to a cutting fluid and a preparation method and an application thereof, especially the application in the processing of niobium-tungsten alloy (NB521). The preparation method of the cutting fluid is simple and requires low production cost. In the mechanical processing of niobium-tungsten alloy (NB521), the cutting fluid has good cooling performance, lubricity, load-bearing capacity, friction reduction and vibration absorption, and long service life. It also can effectively avoid built-up edges, thereby improving the service life of cutting tools and the processibility of materials. Therefore, products of good quality are produced to improve the yield, especially in the deep hole machining, and thus the cutting fluid of the present application is suitable for a wide range of applications.

Abstract: A service control method and a service control apparatus, where the method includes obtaining, a current electricity grid electricity price and a quantity of to-be-executed services, determining an electricity price threshold according to the quantity of the to-be-executed services, decreasing, by the service control apparatus, a quantity of services that are about to be executed by a first quantity when the current electricity grid electricity price is greater than the electricity price threshold, and executing a service according to a reduced quantity of services that are about to be executed, or increasing, by the service control apparatus, a quantity of services that are about to be executed by a second quantity, and executing a service according to an increased quantity of services that are about to be executed when the current electricity grid electricity price is less than the electricity price threshold.

Abstract: A service control method and a service control apparatus, where the method includes obtaining, a current electricity grid electricity price and a quantity of to-be-executed services, determining an electricity price threshold according to the quantity of the to-be-executed services, decreasing, by the service control apparatus, a quantity of services that are about to be executed by a first quantity when the current electricity grid electricity price is greater than the electricity price threshold, and executing a service according to a reduced quantity of services that are about to be executed, or increasing, by the service control apparatus, a quantity of services that are about to be executed by a second quantity, and executing a service according to an increased quantity of services that are about to be executed when the current electricity grid electricity price is less than the electricity price threshold.

Abstract: The present application relates to metal cutting, and more particularly to a cutting fluid and a preparation method and an application thereof, especially the application in the processing of niobium-tungsten alloy (NB521). The preparation method of the cutting fluid is simple and requires low production cost. In the mechanical processing of niobium-tungsten alloy (NB521), the cutting fluid has good cooling performance, lubricity, load-bearing capacity, friction reduction and vibration absorption, and long service life. It also can effectively avoid built-up edges, thereby improving the service life of cutting tools and the processibility of materials. Therefore, products of good quality are produced to improve the yield, especially in the deep hole machining, and thus the cutting fluid of the present application is suitable for a wide range of applications.

Abstract: A memory access method includes: receiving, by the switch, a data packet; matching a flow table on the data packet, where the flow table includes at least one flow entry, where the flow entry includes a matching field and an action field, and the at least one flow entry includes a first flow entry, where a matching field of the first flow entry is used to match source node information, destination node information, and a protocol type in the data packet, and an action field of the first flow entry is used to indicate an operation command for a storage device embedded in the switch; and when the data packet successfully matches the first flow entry, performing an operation on the storage device according to the operation command in the action field of the successfully matched first flow entry.

Abstract: A service control method and a service control apparatus, where the method includes obtaining, a current electricity grid electricity price and a quantity of to-be-executed services, determining an electricity price threshold according to the quantity of the to-be-executed services, decreasing, by the service control apparatus, a quantity of services that are about to be executed by a first quantity when the current electricity grid electricity price is greater than the electricity price threshold, and executing a service according to a reduced quantity of services that are about to be executed, or increasing, by the service control apparatus, a quantity of services that are about to be executed by a second quantity, and executing a service according to an increased quantity of services that are about to be executed when the current electricity grid electricity price is less than the electricity price threshold.