Abstract: The present invention discloses a preparation and a method for improving ring rot resistance of apple fruits and belongs to the technical field of plant disease resistance. Resistance of apple fruits to ring rot may be significantly improved by soaking the fruits with a sorbitol solution. Moreover, the sorbitol solution is effective to multiple varieties; the barrier in control of ring rot through chemical pesticides and the like may be overcome; and pollution of the pesticides and the like to the ecological environment is greatly decreased, thereby decreasing losses caused by occurrence of apple ring rot in a maturation period or a storage period.

Abstract: Provided is a modified immune cell, comprising a chimeric antigen receptor and/or a coding element therefor, or comprising a T cell receptor and/or a coding element therefor. The immune cell further comprises: leptin and/or a functional fragment thereof; and/or, a leptin receptor and/or a functional fragment thereof, and the expression quantity of the leptin receptor and/or the functional fragment thereof in the immune cell is increased compared with that in an immune cell without the corresponding modification. In addition, also provided is another modified immune cell, comprising leptin and/or a functional fragment thereof, and/or, a leptin receptor and/or a functional fragment thereof, and a low-density lipoprotein-receptor-related protein or a fragment thereof.

Abstract: An antibody that binds to the PD-L1 protein or CD137 protein, an antigen-binding fragment or a variant thereof, as well as a bispecific antibody that can bind to both the PD-L1 protein and the CD137 protein. The bispecific antibody has a strong ability to specifically recognize the PD-L1 protein and the CD137 protein, and can enhance T-cell activity. The antibody or the antigen-binding fragment or the variant thereof and the bispecific antibody may be used in the prevention and treatment of tumors.

Abstract: Provided are an antibody that binds to the PD-L1 protein or CD137 protein, an antigen-binding fragment or a variant thereof, as well as a bispecific antibody that can bind to both the PD-L1 protein and the CD137 protein. The bispecific antibody has a strong ability to specifically recognize the PD-L1 protein and the CD137 protein, and can enhance T-cell activity. Also provided is the use of the antibody or the antigen-binding fragment or the variant thereof and the bispecific antibody in the prevention and treatment of tumors.

Abstract: Disclosed is a method for promoting immune cell proliferation. The method comprises the following step: upregulating the expression of low-density lipoprotein receptor-related proteins or fragments thereof in immune cells.

Abstract: Provided are techniques for generating a relational query. Information is collected from a query specification and a model for an On-Line Analytical Processing (OLAP) query having at least a first expression and a second expression. The collected information is used to generate a relational query to retrieve report data to be used to satisfy the first expression and the second expression.

Abstract: Provided are techniques for generating a relational query. Information is collected from a query specification and a model for an On-Line Analytical Processing (OLAP) query having at least a first expression and a second expression. The collected information is used to generate a relational query to retrieve report data to be used to satisfy the first expression and the second expression.

Abstract: The invention introduces a method and system to automatically derive the relationships between query subjects and query items within query subjects so that problems such as those that result in double courting of information are avoided. It provides for creating a report by first defining a model based on an existing database comprising two or more query subjects, each query subject comprising at least one fact query item and one primary key, then generating a hierarchy of sets and subsets of key query items within the model. Next a further fact is introduced into one of the query subjects. The expression is decomposed into sub-queries to prevent double counting of data in ambiguously defined situations. This is achieved using the introduced fact to determine that such decomposition is required. Finally, the data is accessed using the sub-queries, and a report is produced.

Abstract: The invention introduces a method and system to automatically derive the relationships between query subjects and query items within query subjects so that problems such as those that result in double courting of information are avoided. It provides for creating a report by first defining a model based on an existing database comprising two or more query subjects, each query subject comprising at least one fact query item and one primary key, then generating a hierarchy of sets and subsets of key query items within the model. Next a further fact is introduced into one of the query subjects. The expression is decomposed into sub-queries to prevent double counting of data in ambiguously defined situations. This is achieved using the introduced fact to determine that such decomposition is required. Finally, the data is accessed using the sub-queries, and a report is produced.