Patents by Inventor Xiaowen Ren

Xiaowen Ren has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • GLP-1 ANALOGUE, ITS PREPARATION METHODS AND USE THEREOF
    Publication number: 20150274799
    Abstract: Provided is a GLP-1 analogue having the structure as shown in the general formula A: 7HAEX10TFTSX15VSSYLEX22QAAKEFIX30WLX33KGRG37n1X1Cn2X2 ??(general formula A), wherein X10 is glycine or cysteine, X15 is aspartic acid or cysteine, X22 is glycine or cysteine, X30 is alanine or cysteine, X33 is valine or cysteine, and at least one of X10, X15, X22, X30 and X33 is cysteine, X1 and X2 respectively is glycine, alanine or valine, n1=1-30, n2=1-30. The general formula A contains two cysteines to form disulfide bonds. Also provided are the preparation methods and the use of said GLP-1 analogue. Said GLP-1 analogue has a prolonged blood half-life compared with GLP-1, and can be used for the treatment of diabetes and obesity.
    Type: Application
    Filed: February 8, 2012
    Publication date: October 1, 2015
    Applicant: TIANJIN INSTITUTE OF PHARMACEUTICAL RESEARCH
    Inventors: Min Gong, Gang Fu, Weiren Xu, Lida Tang, Xiaowen Ren, Peng Liu, Yuli Wang, Jiang Wu, Meixiang Zou
  • Glycyrrhetinic acid-30-amide derivatives and their use
    Patent number: 7790759
    Abstract: The present invention relates to the field of a medicine for treating diseases associated with inflammation, immunity or infection, and in particular, to glycyrrhetinic acid-30-amide derivatives of general formula I and their preparation, and a pharmaceutical composition containing the same. Said derivatives and composition exhibit anti-inflammatory, analgesic, anti-allergic, cough-preventing, liver-protecting and anti-viral properties, wherein each group is as defined in the description.
    Type: Grant
    Filed: October 16, 2006
    Date of Patent: September 7, 2010
    Assignee: Tianjin Institute of Pharmaceutical Research
    Inventors: Jianwu Wang, Weiren Xu, Jianping Wong, Lida Tang, Shijun Zhang, Lijun Liu, Yuli Wang, Xiaowen Ren
  • Glycyrrhetinic Acid-30-Amide Derivatives and Their Use
    Publication number: 20080214636
    Abstract: The present invention relates to the field of a medicine for treating diseases associated with inflammation, immunity or infection, and in particular, to glycyrrhetinic acid-30-amide derivatives of general formula I and their preparation, and a pharmaceutical composition containing the same. Said derivatives and composition exhibit anti-inflammatory, analgesic, anti-allergic, cough-preventing, liver-protecting and anti-viral properties, wherein each group is as defined in the description.
    Type: Application
    Filed: October 16, 2006
    Publication date: September 4, 2008
    Applicant: TIANJIN INSTITUTE OF PHARMACEUTICAL RESEARCH
    Inventors: Jianwu Wang, Weiren Xu, Jianping Yong, Lida Tang, Shijun Zhang, Lijun Liu, Yuli Wang, Xiaowen Ren