Abstract: Various embodiments may relate to a liquid cooling module. The liquid cooling module may include a main body. The main body may include a cooling core including a microfluidic structure configured to carry a cooling liquid. The main body may also include a plurality of slots. The liquid cooling module may further include a sealing pad configured to transmit heat from an electronic device to the cooling core. The liquid cooling module may additionally include a plurality of fins extending from the main body, each of the plurality of fins including an internal circulating liquid duct such that the liquid cooling module includes a plurality of internal circulating liquid ducts in fluidic communication with the microfluidic structure.

Abstract: A biosensor useful for the detection of a target analyte in a fluid biological sample is provided. The biosensor comprises a first sensing layer comprising at least a pair of metal electrodes on an inert substrate, wherein the electrodes are linked by an electrically conductive bridge having immobilized on the surface thereof analyte-reactive compounds, wherein the electrically conductive electrode bridge comprises a material that responds to binding of target analyte to the analyte-reactive compound with an electrochemical or electrical change; and, optionally, a second layer comprising one or more sample chambers for placement on the first sensing layer, wherein the sample chambers are adapted to receive a fluid sample and direct the sample to the bridge.

Abstract: A device for the detection of a target analyte in solution is provided. The device comprises a gate-keeper membrane made of a substrate having a first receptor surface for exposure to the target analyte and a second opposing surface exposed to a detector, wherein the substrate is adapted to incorporate pores sufficient to permit passage of a reporter through the membrane from exposure to the first receptor surface to the second opposing surface; one or more receptors anchored on the first surface of the substrate which bind with the target analyte, wherein binding of the receptor with the target analyte alters the passage of the reporter through the pores of the membrane; and one or more detectors which interact with reporter that passes through the membrane and emits a detectable signal that permits quantification of reporter in the detection reservoir.

Abstract: A device for the detection of a target analyte in solution is provided. The device comprises a gate-keeper membrane made of a substrate having a first receptor surface for exposure to the target analyte and a second opposing surface exposed to a detector, wherein the substrate is adapted to incorporate pores sufficient to permit passage of a reporter through the membrane from exposure to the first receptor surface to the second opposing surface; one or more receptors anchored on the first surface of the substrate which bind with the target analyte, wherein binding of the receptor with the target analyte alters the passage of the reporter through the pores of the membrane; and one or more detectors which interact with reporter that passes through the membrane and emits a detectable signal that permits quantification of reporter in the detection reservoir.