Abstract: The present disclosure provides a liquid cooling plate and battery pack. The liquid cooling plate is formed with a receiving space. The liquid cooling plate includes a first cooling plate and a second cooling plate. The second cooling plate is stacked on a side of the first cooling plate facing the receiving space and is connected to the first cooling plate in a sealed manner. A cooling flow passage surrounding the receiving space is formed between the second cooling plate and the first cooling plate.

Abstract: Disclosed are a display substrate, a liquid crystal display panel (100) and a display device. The display substrate (9) includes: a base substrate (1), a plurality of sub-pixels arranged in an array on the base substrate, a plurality of data lines (D) extending in a first direction (X), a plurality of gate lines (G) extending in a second direction (Y), and a common electrode (2) arranged in a minimum area enclosed by the data lines and the gate lines; wherein the minimum area includes two sub-pixels, the common electrode includes a main electrode (21) with strip-shaped which is arranged at the junction of the two sub-pixels and a plurality of branch electrodes (22) with strip-shaped which are symmetrically distributed on two sides of the main electrode, and the extending directions of a part of the plurality of branch electrodes arranged on a same side of the main electrode are identical.

Abstract: Provided is a GII.4 norovirus virus-like particle or active fragment thereof, and use thereof, the virus-like particle comprising or being composed of an amino acid sequence shown as SEQ ID NO: 4. Further, provided is a composition or a kit comprising the GII.4 norovirus virus-like particle, and use thereof. The objective of covering multiple genotypes is achieved by using a single antigen of the invention, the process difficulty of the preparation for a pharmaceutical composition or a vaccine can be reduced, and the production cost is decreased. Also, provided is a norovirus immune composition or a kit comprising GII.2, GII.4, GII.6, and GII.17 norovirus virus-like particles or active fragments thereof, and use thereof.

Abstract: A high-speed machining tool made of a steel-bonded carbide and a method for preparing the same relate to the technical field of lathe tools made of steel-bonded carbides, and overcome the problems of traditional steel-bonded carbide lathe tools about low hardness and low toughness. The high-speed machining tool includes a skeleton, a main body, and a coating. The main body is consolidated by the skeleton from inside. The skeleton and the main body are both ringlike in shape. The main body has its outer surface covered by the coating. The high-speed machining tool is such made that the skeleton is hard and the main body is tough. The blade of the tool is hard and can transfer vibrations to the main body, thereby protecting the tool from brittle fractures and improving the overall performance of the tool.

Abstract: A high-speed machining tool made of a steel-bonded carbide and a method for preparing the same relate to the technical field of lathe tools made of steel-bonded carbides, and overcome the problems of traditional steel-bonded carbide lathe tools about low hardness and low toughness. The high-speed machining tool includes a skeleton, a main body, and a coating. The main body is consolidated by the skeleton from inside. The skeleton and the main body are both ringlike in shape. The main body has its outer surface covered by the coating. The high-speed machining tool is such made that the skeleton is hard and the main body is tough. The blade of the tool is hard and can transfer vibrations to the main body, thereby protecting the tool from brittle fractures and improving the overall performance of the tool.

Abstract: The present invention generally pertains to methods of characterizing at least one protein of interest in a biological sample. In particular, the present invention pertains to the use of automated iterative tandem mass spectrometry (AIMS) to identify, quantify and characterize at least one protein of interest and/or biomarker from a biological sample such as plasma.

Abstract: The present invention provides methods and systems for isotyping and quantification of antibodies based on immunocapture and/or Liquid Chromatography-Mass Spectrometry (LC-MS) analysis. These antibodies are induced by the administration of pharmaceutical products. The immunocapture method comprises contacting samples with a solid support, wherein the pharmaceutical product has been cross-linked directly to the solid support. The MS analysis includes conducting peptide mapping, selecting unique peptides and fragment ions to generate MRM (multiple reaction monitoring) transitions, optimizing collision energy, and determining a LLOQ (lower limit of quantification).