Patents by Inventor Xiaoxing S. Xu

Xiaoxing S. Xu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of modulating tumor necrosis factor .alpha.-induced expression of cell adhesion molecules
    Patent number: 6114517
    Abstract: Methods are provided for inhibiting the expression of cell adhesion molecules using inhibitors of signaling molecules involved in human TNF-.alpha. signaling. These inhibitors include monoclonal antibodies, peptide fragments, small molecule inhibitors, and, preferably, antisense oligonucleotides. Methods for treatment of diseases, particularly inflammatory and immune diseases, associated with overexpression of cell adhesion molecules are provided.
    Type: Grant
    Filed: December 10, 1998
    Date of Patent: September 5, 2000
    Assignee: Isis Pharmaceuticals Inc.
    Inventors: Brett P. Monia, Xiaoxing S. Xu