Patents by Inventor Xiaoxu WANG

Xiaoxu WANG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Obstacle-surmounting walking device
    Patent number: 12780336
    Abstract: An obstacle-surmounting walking device is provided, and belongs to the technical field of walking devices. The obstacle-surmounting walking device includes a contact wheel, a driving load-bearing wheel, a free climbing wheel, a climbing drive disc, a climbing drive disc driving disengagement leaf, and a driving device. Contact wheel climbing teeth are arranged on contact wheel rim on the contact wheel, and contact wheel spokes of the contact wheel deviates from a center of the contact wheel rim. The driving load-bearing wheel is fixed on a driving wheel axle, and a bottom end of the driving load-bearing wheel is in contact with an inner surface of the contact wheel rim. A bottom end of the free climbing wheel is engaged with the contact wheel climbing teeth, the free climbing wheel can freely rotate around the driving wheel axle.
    Type: Grant
    Filed: July 3, 2024
    Date of Patent: November 3, 2026
    Assignee: DALIAN UNIVERSITY OF TECHNOLOGY
    Inventors: Xiaoxu Wang, Jinglong Wang, Hui Liu
  • MACROCYCLIC SULFONAMIDE MODULATORS
    Publication number: 20260109711
    Abstract: Disclosed are compounds, compositions, and methods useful for preventing or treating a disease which is at least partially mediated by orexin receptor 2.
    Type: Application
    Filed: September 17, 2025
    Publication date: April 23, 2026
    Applicant: Vertex Pharmaceuticals Incorporated
    Inventors: Jun Myun AHN, Emily Elizabeth ALLEN, David John CHARBONEAU, Ming CHEN, Leslie A. DAKIN, Christina Anne DE BRUYN KOPS, Travis Jon DELANO, Pedro Manuel GARCIA BARRANTES, Ronald Lee GREY, JR., Megan Elizabeth HOERRNER, Sheila NAMIREMBE, Arjun Venkat NARAYANAN, Jessica Howard OLSEN, Madison Henry POWERS, Tony Z. SCOTT, Steven David STONE, Emil Francois THOMAS, Xiaoxu WANG, Ashley K. Z. ZACHMANN, Mariam ZAKY, Chenlong ZHANG
  • OBSTACLE-SURMOUNTING WALKING DEVICE
    Publication number: 20250206392
    Abstract: An obstacle-surmounting walking device is provided, and belongs to the technical field of walking devices. The obstacle-surmounting walking device includes a contact wheel, a driving load-bearing wheel, a free climbing wheel, a climbing drive disc, a climbing drive disc driving disengagement leaf, and a driving device. Contact wheel climbing teeth are arranged on contact wheel rim on the contact wheel, and contact wheel spokes of the contact wheel deviates from a center of the contact wheel rim. The driving load-bearing wheel is fixed on a driving wheel axle, and a bottom end of the driving load-bearing wheel is in contact with an inner surface of the contact wheel rim. A bottom end of the free climbing wheel is engaged with the contact wheel climbing teeth, the free climbing wheel can freely rotate around the driving wheel axle.
    Type: Application
    Filed: July 3, 2024
    Publication date: June 26, 2025
    Inventors: XIAOXU WANG, JINGLONG WANG, HUI LIU
  • Smooth obstacle-crossing walking mechanism
    Patent number: 12090779
    Abstract: The present disclosure belongs to the technical field of walking mechanisms, and provides a smooth obstacle-crossing walking mechanism, which can provide strong smooth obstacle crossing capability, meanwhile, maintains lower friction loss and higher efficiency, and is suitable for most daily use situations. A smooth obstacle-crossing walking mechanism includes a driving wheel and a contact wheel. The driving wheel has a wheel diameter lower than that of the contact wheel. The driving wheel compresses an inner edge of the contact wheel under gravity. The contact wheel is in contact with the ground surface. When the driving wheel rotates actively, it walks along the inner edge of the contact wheel under the frictional force with the contact wheel. The contact wheel rolls forwards under a pressure and the frictional force of the driving wheel, so as to enable the smooth obstacle-crossing walking mechanism to walk.
    Type: Grant
    Filed: August 13, 2021
    Date of Patent: September 17, 2024
    Assignee: Dalian University of Technology
    Inventors: Xiaoxu Wang, Kangsheng Lai, Jinglong Wang
  • MODULATORS OF ALPHA-1 ANTITRYPSIN
    Publication number: 20240158404
    Abstract: Novel compounds, compositions, and methods of using and preparing the same, which may be useful for treating alpha-1 antitrypsin deficiency (AATD).
    Type: Application
    Filed: September 8, 2023
    Publication date: May 16, 2024
    Inventors: Ronald Lee Grey, JR., Emily Elizabeth Allen, Michael J. Boyd, Robert F. Fimognari, JR., Simon Giroux, Michelle Lai-Chen, Ales Medek, Mengqi Li, Christopher David Poff, Daniel Tyler Richter, Tony Z. Scott, Kathleen Paige Sokolowsky, Jeffrey Braden Sperry, Charlene Tsay, Xiaoxu Wang, Mariam Zaky, Chenlong Zhang
  • CONJUGATES OF A CELL-BINDING MOLECULE WITH CAMPTOTHECIN ANALOGS
    Publication number: 20230241241
    Abstract: This invention relates to conjugates of camptothecin analogs with a cell-binding molecule of formula (I), wherein R1, R2, R3, R4, R5, X, L, n, m, T and ----- are defined herein. It also provides methods of making the conjugates of camptothecin analogs to a cell-binding agent, as well as methods of using the conjugates in targeted treatment of cancer, infection, and immunological disorders.
    Type: Application
    Filed: June 19, 2020
    Publication date: August 3, 2023
    Applicant: HANGZHOU DAC BIOTECH CO., LTD.
    Inventors: Robert ZHAO, Qingliang YANG, Hangbo YE, Yuanyuan HUANG, Yifang XU, Gengxiang ZHAO, Diancheng CHEN, Huihui GUO, Xiangfei KONG, Wenjun LI, Lu BAI, Xiang CAI, Xiuzhen ZHANG, Junxiang JIA, Zhixiang GUO, Shangma HUANG, Xiaoxu WANG, Jun ZHENG, Yong DU, Yanhua LI, Yunxia ZHENG, Chen LIN, Xiaoxiao CHEN, Wei ZHENG, Xinyan JIANG, Lingli ZHANG, Riping YE, Miaomiao CHEN
  • SMOOTH OBSTACLE-CROSSING WALKING MECHANISM
    Publication number: 20220219487
    Abstract: The present disclosure belongs to the technical field of walking mechanisms, and provides a smooth obstacle-crossing walking mechanism, which can provide strong smooth obstacle crossing capability, meanwhile, maintains lower friction loss and higher efficiency, and is suitable for most daily use situations. A smooth obstacle-crossing walking mechanism includes a driving wheel and a contact wheel. The driving wheel has a wheel diameter lower than that of the contact wheel. The driving wheel compresses an inner edge of the contact wheel under gravity. The contact wheel is in contact with the ground surface. When the driving wheel rotates actively, it walks along the inner edge of the contact wheel under the frictional force with the contact wheel. The contact wheel rolls forwards under a pressure and the frictional force of the driving wheel, so as to enable the smooth obstacle-crossing walking mechanism to walk.
    Type: Application
    Filed: August 13, 2021
    Publication date: July 14, 2022
    Inventors: Xiaoxu WANG, Kangsheng LAI, Jinglong WANG