Patents by Inventor Xiaoya Pan

Xiaoya Pan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Manipulation of Regulatory T Cell and Dc Function By Targeting Neuritin Gene Using Antibodies, Agonists and Antagonists
    Publication number: 20100040636
    Abstract: We demonstrate herein that neuritin controls the homeostasis of regulatory T cells in an antigen dependent manner. Based on this discovery, we describe herein the application of neuritin as a therapeutic agent to manipulate antigen specific regulatory T cells in various disease settings is described. Thus manipulation of Treg cells and DCs through neuritin can be used to enhance immunotherapy of autoimmune diseases, cancer and infectious diseases, as well as enhance lymphocyte engraftment in settings of donor lymphocyte infusion, bone marrow transplant, as well as other types of transplants, and adoptive transfer.
    Type: Application
    Filed: September 11, 2006
    Publication date: February 18, 2010
    Applicant: The Johns Hopkins University
    Inventors: Hong Yu, Drew Pardoll, Xiaoya Pan, Charles George Drake, Jonathan D. Powell, Ching-Tai Huang