Patents by Inventor Xiaoyan Gao

Xiaoyan Gao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240102025
    Abstract: The present disclosure provides a gene combination for expressing and producing terrequinone A in Escherichia coli and use thereof. The gene combination includes a tdiAS gene, a tdiBS gene, a tdiCS gene, a tdiDS gene, a tdiES gene, an sfpS gene, an ScCKS gene, and an AtIPKS gene with nucleotide sequences set forth in SEQ ID NOS:1 to 8. In the present disclosure, a recombinant engineered strain capable of producing terrequinone A having anti-cancer activity is obtained by separately constructing recombinant plasmids pC02 and pU03 through the eight genes and transforming the two recombinant plasmids into E. coli. The content of terrequinone A in a fermentation broth thereof is 106.3 mg/L, which has potential application value in the biopharmaceutical field.
    Type: Application
    Filed: May 24, 2023
    Publication date: March 28, 2024
    Inventors: Yongsheng TIAN, Lijuan WANG, Yongdong DENG, Quanhong YAO, Rihe PENG, Jianjie GAO, Zhenjun LI, Wenhui ZHANG, Bo WANG, Jing XU, Yu WANG, Xiaoyan FU, Hongjuan HAN
  • Patent number: 11922335
    Abstract: The present disclosure relates to a method and system for evaluating the macro resilience of offshore oil well control equipment. The method for evaluating the macro resilience of offshore oil well control equipment comprises six steps: determining the type and strength of external disaster; calculating the failure rate of components; calculating the recovery rate of the components; modeling the BN for a degradation process; modeling the BN for a maintenance process; and calculating the resilience of the offshore oil well control equipment. A system for evaluating the macro resilience of offshore oil well control equipment comprises an external disaster evaluation module, a component failure rate calculation subsystem, a reliability degradation process simulation module, a fault identification module, a component recovery rate calculation module, a reliability recovery process simulation module, a reliability change curve derivation unit and an resilience calculation unit.
    Type: Grant
    Filed: December 5, 2019
    Date of Patent: March 5, 2024
    Assignee: China University of Petroleum (East China)
    Inventors: Baoping Cai, Yonghong Liu, Yanping Zhang, Chuntan Gao, Xiaoyan Shao, Hongqi Xu, Xincheng Li, Yandong Chen, Renjie Ji, Zengkai Liu, Libing Liu, Rikui Zhang, Yuqian Yang, Shitang Liu, Xin Wei
  • Patent number: 11766004
    Abstract: A drip irrigation apparatus and system. The drip irrigation apparatus includes a flow channel body and an elastic body. The elastic body is mounted on the outer circumference of the flow channel body and fitted in a spontaneous state to the outer circumference of the flow channel body. The flow channel body includes an energy dissipation body. The first drainage channel is formed in the energy dissipation body, the first drainage channel is connected to both ends of the energy dissipation body. The first drainage channel is connected at both ends of the first drainage channel to the inner wall of the elastic body forming a radial drainage channel.
    Type: Grant
    Filed: November 12, 2021
    Date of Patent: September 26, 2023
    Assignees: CHINA INSTITUTE OF WATER RESOURCES AND HYDROPOWER RESEARCH, BEIJING AITEFU WATER SAVING TECHNOLOGY CO., LTD.
    Inventors: Yan Mo, Jiandong Wang, Yanqun Zhang, Qiaoling Li, Shihong Gong, Di Xu, Xiaoyan Gao
  • Patent number: 11726003
    Abstract: A test platform for an automatic flushing valve is described. It includes a fluid source, weighing parts, a bracket, a diverter and several driplines. The driplines are parallel to each other and are evenly arranged in an array in a circumferential direction of the diverter. Emitters are installed on each of the driplines; one end of each driplines is fixed to the diverter, which is connected to the fluid source to feed fluid into the driplines. The diverter is pivotally connected to the bracket, so that the diverter and the driplines can pivot relative to the bracket; the other end of each driplines is used to install automatic flushing valves. Weighing parts are installed below the automatic flushing valves to measure the solution flowing out of the automatic flushing valves, and other weighing parts are installed below the driplines to measure solution flowing out of the emitters.
    Type: Grant
    Filed: November 30, 2022
    Date of Patent: August 15, 2023
    Assignee: CHINA INSTITUTE OF WATER RESOURCES AND HYDROPOWER RESEARCH
    Inventors: Yan Mo, Jiandong Wang, Yanqun Zhang, Qiaoling Li, Shihong Gong, Xiaoyan Gao
  • Publication number: 20230168147
    Abstract: A test platform for an automatic flushing valve is described. It includes a fluid source, weighing parts, a bracket, a diverter and several driplines. The driplines are parallel to each other and are evenly arranged in an array in a circumferential direction of the diverter. Emitters are installed on each of the driplines; one end of each driplines is fixed to the diverter, which is connected to the fluid source to feed fluid into the driplines. The diverter is pivotally connected to the bracket, so that the diverter and the driplines can pivot relative to the bracket; the other end of each driplines is used to install automatic flushing valves. Weighing parts are installed below the automatic flushing valves to measure the solution flowing out of the automatic flushing valves, and other weighing parts are installed below the driplines to measure solution flowing out of the emitters.
    Type: Application
    Filed: November 30, 2022
    Publication date: June 1, 2023
    Inventors: Yan MO, Jiandong WANG, Yanqun ZHANG, Qiaoling LI, Shihong GONG, Xiaoyan GAO
  • Publication number: 20230091895
    Abstract: Disclosed is an antibody capable of specifically recognizing PCSK9 or an antigen-binding fragment thereof. The antibody comprises heavy chain variable region CDR1, CDR2, and CDR3 sequences shown in SEQ ID NO: 1, SEQ ID NO: 2, and SEQ ID NO: 3 or shown in amino acid sequences having at least 95% identity to SEQ ID NO: 1, SEQ ID NO: 2, and SEQ ID NO: 3. The antibody can specifically bind to PCSK9 and inhibit the activity of PCSK9.
    Type: Application
    Filed: August 9, 2022
    Publication date: March 23, 2023
    Applicant: BGI SHENZHEN
    Inventors: Naibo Yang, Xiaoyan Gao, Xinyang Li, Xinhua Zhang, Meiniang Wang
  • Publication number: 20220142064
    Abstract: A drip irrigation apparatus and system. The drip irrigation apparatus includes a flow channel body and an elastic body. The elastic body is mounted on the outer circumference of the flow channel body and fitted in a spontaneous state to the outer circumference of the flow channel body. The flow channel body includes an energy dissipation body. The first drainage channel is formed in the energy dissipation body, the first drainage channel is connected to both ends of the energy dissipation body. The first drainage channel is connected at both ends of the first drainage channel to the inner wall of the elastic body forming a radial drainage channel.
    Type: Application
    Filed: November 12, 2021
    Publication date: May 12, 2022
    Inventors: Yan MO, Jiandong WANG, Yanqun ZHANG, Qiaoling LI, Shihong GONG, Di XU, Xiaoyan GAO
  • Patent number: 11328926
    Abstract: The present invention relates to the field of chemical industry, and discloses organosilicone micro-mesoporous ultra-low dielectric thin films and preparation methods therefor. A structural formula of a POSS-based organosilane precursor in the thin film is as follows: where n is 12, 16, 18, 20, or 22, and X is CH3 or CH2CH3. The preparation method includes the following steps: dissolving a certain amount of the POSS-based precursor in an organic solvent at a room temperature; adding an appropriate amount of a photoacid generator, after uniformly stirring, spraying a mixed liquid to form a film on a substrate; placing the substrate under a light-emitting diode lamp for irradiating for a preset time after the organic solvent is completely evaporated; then placing the substrate in N,N-dimethylformamide for undergoing a transesterification reaction with fluoroalkyl alcohol for 24-72 h; and washing and drying to obtain the organosilicone micro-mesoporous ultra-low dielectric thin film.
    Type: Grant
    Filed: October 9, 2018
    Date of Patent: May 10, 2022
    Assignee: HUAIYIN INSTITUTE OF TECHNOLOGY
    Inventors: Lingli Ni, Yongtao Liu, Tao Xie, Minhua Xu, Zhitian Chen, Peng Chai, Xiaoyan Gao, Liang Dong Feng, Shizhong Zhang
  • Publication number: 20210175074
    Abstract: The present invention relates to the field of chemical industry, and discloses organosilicone micro-mesoporous ultra-low dielectric thin films and preparation methods therefor. A structural formula of a POSS-based organosilane precursor in the thin film is as follows: where n is 12, 16, 18, 20, or 22, and X is CH3 or CH2CH3. The preparation method includes the following steps: dissolving a certain amount of the POSS-based precursor in an organic solvent at a room temperature; adding an appropriate amount of a photoacid generator, after uniformly stirring, spraying a mixed liquid to form a film on a substrate; placing the substrate under a light-emitting diode lamp for irradiating for a preset time after the organic solvent is completely evaporated; then placing the substrate in N,N-dimethylformamide for undergoing a transesterification reaction with fluoroalkyl alcohol for 24-72 h; and washing and drying to obtain the organosilicone micro-mesoporous ultra-low dielectric thin film.
    Type: Application
    Filed: October 9, 2018
    Publication date: June 10, 2021
    Inventors: Lingli NI, Yongtao LIU, Tao XIE, Minhua XU, Zhitian CHEN, Peng CHAI, Xiaoyan GAO, Liang Dong FENG, Shizhong ZHANG
  • Publication number: 20200299448
    Abstract: The present invention relates to the field of chemical industries, and discloses a method for synthesizing a highly weather-resistant red waterborne polyurethane emulsion, including using oligomeric diol, aliphatic diisocyanate, iron-rich red attapulgite clay, and a hydrophilic chain extender for stepwise polymerization to synthesize a red attapulgite clay modified hydrophilic polyurethane prepolymer, then self-emulsifying and dispersing in metered water, and then adding a small molecule diamine chain extender for chain extension to obtain a red attapulgite clay modified red waterborne polyurethane emulsion. The preparation method of the present invention is easy to operate, energy-saving and environmentally friendly. The prepared red waterborne polyurethane emulsion has a solid content>30 wt. % and the pH between 6.0 and 7.0, and its coating product has the advantages of good water resistance, high weather resistance, vivid color, etc., and has a broad market prospect.
    Type: Application
    Filed: January 8, 2019
    Publication date: September 24, 2020
    Inventors: Yu MAO, Lingli NI, Yongtao LIU, Xiaoyan GAO, Peng CAI, Jing CHENG, Guijun LI
  • Publication number: 20150371481
    Abstract: A banknote recognition apparatus, a processing method thereof and a method for recording a banknote processing state are disclosed. The banknote recognition apparatus includes a nonvolatile memory (14) and a control unit (11) configured to record a state of an event to the nonvolatile memory (14) during a banknote processing process, wherein the event is a key step in the banknote processing process. The apparatus and the method solve a problem that an abnormity often occurs when the banknote recognition apparatus stores banknote processing information to the nonvolatile memory (14) upon a power failure, thus the banknote processing information can be stored effectively when the power failure occurs on the banknote recognition apparatus.
    Type: Application
    Filed: January 20, 2014
    Publication date: December 24, 2015
    Inventors: Chunkai Xu, Shishui Zhang, Xiaoyan Gao
  • Publication number: 20110204077
    Abstract: A paper cutting control device for ticket paper and ticket dispensing machine comprising the same, wherein the paper cutting control device for ticket paper comprises a driving motor (M), a first sensor (2), a cutter (3), a controller and a second sensor (4). The first sensor is located on an upstream of the cutter and used for detecting a spacing mark (B) between adjacent tickets of the ticket paper and sending a spacing mark arrival signal when the spacing mark is detected. The second sensor is located on a downstream of the cutter and used for detecting a front end of the ticket paper and sending a ticket arrival signal when the front end of the ticket paper is detected. A ticket dispensing machine has the paper cutting control device for ticket paper.
    Type: Application
    Filed: October 28, 2009
    Publication date: August 25, 2011
    Inventors: Changgang Gu, Zhigang Xu, Lei Che, Weiwei Xu, Xiaoyan Gao