Abstract: The present description relates to methods of treating neurodegenerative diseases characterized by the accumulation of aberrant forms of the microtubule associated protein Tau (MAPT) using substituted thieno[3,2-b]pyridine compounds, forms, and pharmaceutical compositions thereof.

Abstract: The present description relates to methods of treating neurodegenerative diseases characterized by the accumulation of aberrant forms of the microtubule associated protein Tau (MAPT) using substituted pyrrolo[2,3-d]pyrimidine compounds, forms, and pharmaceutical compositions thereof.

Abstract: The present disclosure relates to a substituted 1,4-dihydro-1,6-naphthyridine amide and a use thereof. Specifically, a compound represented by formula I or a pharmaceutically acceptable salt thereof is provided, where R1, R3-R11, Z1 and Z2 are as defined in the present disclosure.

Abstract: The present description relates to methods of treating neurodegenerative diseases characterized by the accumulation of aberrant forms of the microtubule associated protein Tau (MAPT) using substituted thieno[3,2-d]pyrimidine compounds, forms, and pharmaceutical compositions thereof.

Abstract: Disclosed are a composite zeolite SCR catalyst, a preparation method therefor and use thereof. The composite zeolite SCR catalyst comprises a Cu-based zeolite and a first hydrogen-type zeolite; the composite zeolite SCR catalyst has a NOx removal efficiency of more than or equal to 80% at more than or equal to 300° C.; the composite zeolite SCR catalyst is subjected to hydrothermal treatment at 750-950° C. for 10-16 h, and the hydrothermally treated composite zeolite SCR catalyst has a NOx removal efficiency of more than or equal to 60% at more than or equal to 300° C. The composite zeolite SCR catalyst of the present application is used in the technology of selective catalytic reduction on nitrogen oxides with ammonia, and the composite zeolite SCR catalyst has simple composition, low preparation cost, great catalytic performance and good hydrothermal stability.

Abstract: A structure self-adjusting type vehicle-mounted magnetic suspension flywheel battery coping with multiple operation modes and an operating method thereof are provided. An ant-nest type channel is formed in a radiator of the flywheel battery along a circumferential direction, and a plurality of counterweight magnetic adsorption devices are symmetrically embedded in a flywheel lower sphere. When the flywheel battery operates in a charging mode, a standby mode or a discharging mode, the operation mode of the motor is flexibly changed according to different recovered energy levels or output energy levels, and the loss in the magnetic bearing system is reduced through matching of different types of magnetic bearings according to different disturbance levels. The low-loss, high-safety and stable operation of the vehicle-mounted magnetic suspension flywheel battery in various operation modes can be realized.

Abstract: A pharmaceutical composition and use of a multi-kinase inhibitor. The present invention relates to the technical field of medicines, and relates to the pharmaceutical composition and use of the multi-kinase inhibitor. The pharmaceutical composition comprises: (a) a compound represented by general formula (I) or a pharmaceutically acceptable salt, a stereoisomer or a crystal form thereof, wherein P1, W1, Y1, and Ar in general formula (I) are as described herein; and (b) a paclitaxel drug. Variables in the general formula are as defined in the description. Studies have shown that the compound of general formula (I) or the pharmaceutically acceptable salt, stereoisomer or crystal form thereof in the present invention has a significant synergistic interaction with the paclitaxel drug in combination for treating cancers.

Abstract: The present disclosure relates to gutta-percha containing carbon nanotubes and a preparation method therefor. The gutta-percha is prepared by mixing a raw material, prepared from the following components of eucommia ulmoide gum, zinc oxide and carbon nanotubes, and extruding the mixed raw material. An orientation factor of the carbon nanotubes in the gutta-percha is greater than 10.8. The preparation method comprises: mixing the components according to dosages, and extruding a mixed product to prepare the gutta-percha containing carbon nanotubes.

Abstract: Methods, systems, and apparatus, including computer programs encoded on computer-storage media, for memory mapping to enhance data cube performance. In some implementations, a system accesses a data set that includes data to be processed into a data cube. The system generates a memory-mapped data cube that includes a plurality of files including different segments of the data cube. Generating the memory-mapped data cube includes allocating memory-mapped buffers in non-volatile data storage and responding to subsequent memory allocation requests with addresses for the buffers such that components of the data cube are accumulated in the buffers. The memory-mapped data cube is loaded by storing the files of the data cube in disk-based storage, mapping the stored files of the data cube to virtual memory addresses, and caching portions of the data cube in random-access memory.

Abstract: Methods, systems, and apparatus, including computer programs encoded on computer-storage media, for memory mapping to enhance data cube performance. In some implementations, a system accesses a data set that includes data to be processed into a data cube. The system generates a memory-mapped data cube that includes a plurality of files including different segments of the data cube. Generating the memory-mapped data cube includes allocating memory-mapped buffers in non-volatile data storage and responding to subsequent memory allocation requests with addresses for the buffers such that components of the data cube are accumulated in the buffers. The memory-mapped data cube is loaded by storing the files of the data cube in disk-based storage, mapping the stored files of the data cube to virtual memory addresses, and caching portions of the data cube in random-access memory.

Abstract: The present disclosure relates to a display method. In one example method, a display is covered by a transparent panel. A location on the transparent panel and corresponding to a first area of the display has a cylindrical curved surface. An optical deformation parameter of a first area of the display is obtained. According to the optical deformation parameter of the first area, a shape of first image data is converted to obtain second image data. The first image data is image data to be displayed in the first area. The second image data is displayed in the first area.

Abstract: A terminal includes a cover, a display module, and a metal middle frame. The display module is located between the cover and the metal middle frame, and the metal middle frame is grounded. The terminal further includes a conducting layer, where the conducting layer is attached to a lower surface of the display module, and at least one gap exists between the conducting layer and the metal middle frame. The conducting layer, the metal middle frame, and the at least one gap form at least one capacitor, where a capacitance change of the at least one capacitor reflects a magnitude of at least one pressure acted on the cover.

Abstract: The present disclosure relates to a display method. In one example method, a display is covered by a transparent panel. A location on the transparent panel and corresponding to a first area of the display has a cylindrical curved surface. An optical deformation parameter of a first area of the display is obtained. According to the optical deformation parameter of the first area, a shape of first image data is converted to obtain second image data. The first image data is image data to be displayed in the first area. The second image data is displayed in the first area.

Abstract: An electronic device includes: a foam is located below an OLED display, and a film is located below the foam. Multiple bridge circuits are disposed on the film. Each bridge circuit includes two parallel branches. A first branch includes a first and a third resistor. A second branch includes a second and a fourth resistor. At least one of the four resistors is bonded to the foam. At least one resistor is not bonded to the foam. The resistor that is bonded to the foam is made from a first material. A strain sensitivity coefficient of the first material is greater than 100. A film area in which the resistor that is bonded to the foam is located is covered by a second material. A Young's modulus of the second material is greater than 30.

Abstract: A method is provided for processing a dual-energy CT scan image, which includes filtering the pixels in a dual-energy CT scan image to obtain pixels to be grouped; grouping the pixels to be grouped into a plurality of pixel groups based on the positions of the pixels to be grouped in the dual-energy CT scan image; performing material decomposition on the pixels in each pixel group; and determining the object corresponding to each pixel group based on the results of material decomposition. By using the method, the scan time and the X-ray dose radiated to a target (e.g., a user to be diagnosed) are reduced.

Abstract: An electronic device includes: a foam is located below an OLED display, and a film is located below the foam. Multiple bridge circuits are disposed on the film. Each bridge circuit includes two parallel branches. A first branch includes a first and a third resistor. A second branch includes a second and a fourth resistor. At least one of the four resistors is bonded to the foam. At least one resistor is not bonded to the foam. The resistor that is bonded to the foam is made from a first material. A strain sensitivity coefficient of the first material is greater than 100. A film area in which the resistor that is bonded to the foam is located is covered by a second material. A Young's modulus of the second material is greater than 30.