Patents by Inventor Xiaoyang Lin

Xiaoyang Lin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • DEAD ANTIGEN STIMULATED IMMATURE HETEROGENOUS DENDRITIC CELLS AS THERAPEUTICS FOR DISEASES
    Publication number: 20200338173
    Abstract: Disclosed herein are exogenous antigen sensitized immature dendritic cells. The dendritic cell may also be dead. The exogenous antigen sensitized immature dendritic cells may be used to elicit an increased immune response. Further provided are vaccines comprising the exogenous antigen sensitized immature dendritic cells, methods, of inducing an immune response in a patient, and methods of treating a disease.
    Type: Application
    Filed: January 18, 2019
    Publication date: October 29, 2020
    Inventors: Chuanhai Cao, Xiaoyang Lin, Yuzhu Hong
  • Methods, antibodies, and vaccines utilizing epitopes of alpha synuclein for treatment of Parkinson's disease
    Patent number: 10653759
    Abstract: The present invention pertains to a dendritic cell-based vaccine against rh-?-Syn, ?-synuclein specific peptide antibodies and related vaccines, and methods of treating, inhibiting, and/or vaccinating against Parkinson's Disease (PD), or symptoms thereof.
    Type: Grant
    Filed: December 14, 2018
    Date of Patent: May 19, 2020
    Assignee: UNIVERSITY OF SOUTH FLORIDA
    Inventors: Chuanhai Cao, Xiaoyang Lin
  • Methods, Antibodies, and Vaccines Utilizing Epitopes of Alpha Synuclein for Treatment of Parkinson's Disease
    Publication number: 20190125847
    Abstract: The present invention pertains to a dendritic cell-based vaccine against rh-?-Syn, ?-synuclein specific peptide antibodies and related vaccines, and methods of treating, inhibiting, and/or vaccinating against Parkinson's Disease (PD), or symptoms thereof.
    Type: Application
    Filed: December 14, 2018
    Publication date: May 2, 2019
    Applicant: University of South Florida
    Inventors: CHUANHAI CAO, XIAOYANG LIN
  • Methods, antibodies, and vaccines utilizing epitopes of alpha synuclein for treatment of parkinsons disease
    Patent number: 10155030
    Abstract: The present invention pertains to a dendritic cell-based vaccine against rh-?-Syn, ?-synuclein specific peptide antibodies and related vaccines, and methods of treating, preventing, and/or vaccinating against Parkinson's Disease (PD), or symptoms thereof.
    Type: Grant
    Filed: May 26, 2015
    Date of Patent: December 18, 2018
    Assignee: University of South Florida
    Inventors: Chuanhai Cao, Xiaoyang Lin
  • Methods, Antibodies, and Vaccines Utilizing Epitopes of Alpha Synuclein for Treatment of Parkinsons Disease
    Publication number: 20170196948
    Abstract: The present invention pertains to a dendritic cell-based vaccine against rh-?-Syn, ?-synuclein specific peptide antibodies and related vaccines, and methods of treating, preventing, and/or vaccinating against Parkinson's Disease (PD), or symptoms thereof.
    Type: Application
    Filed: May 26, 2015
    Publication date: July 13, 2017
    Applicant: University of South Florida
    Inventors: Chuanhai Cao, Xiaoyang Lin
  • IMMUNOTHERAPY FOR TREATMENT OF AMYLOID-RELATED DISORDERS USING ENCAPSULATED BETA-AMYLOID PEPTIDES
    Publication number: 20140170225
    Abstract: The present invention relates to the field of polymer chemistry and more particularly to encapsulated peptides and uses thereof.
    Type: Application
    Filed: August 1, 2013
    Publication date: June 19, 2014
    Inventors: CHUANHAI CAO, XIAOYANG LIN, KURT BREITENKAMP, HABIB SKAFF, KEVIN N. SILL
  • Method of diagnosing or assessing risk for Parkinson's disease or Alzheimer's disease using TCR clonality
    Patent number: 8383347
    Abstract: Changes in adaptive immune system were identified and correlated as a predictor of A?40 and A?42 and AD progression. T-cell, B-cell, TCR and BCR profiles were used to correlate clinical progression of AD. The CDR3 region was spectratyped, showing the clonality of the CDR3 region. This intrafamily gene fragment length profile was compared to age-matched controls, thereby indicating the existence of a neurodegenerative disease. The novel method is useful in diagnosing neurodegenerative disease, like Parkinson's disease, HIV-associated Dementia, or Alzheimer's disease. Moreover, this permits the clinical identification of patients at a very early stage of AD and/or monitoring the potential benefits of disease modifying therapeutics.
    Type: Grant
    Filed: May 3, 2010
    Date of Patent: February 26, 2013
    Assignee: University of South Florida
    Inventors: Chuanhai Cao, Xiaoyang Lin, Huntington Potter
  • Immunotherapy for Treatment of Amyloid-Related Disorders Using Encapsulated Beta-Amyloid Peptides
    Publication number: 20100136063
    Abstract: The present invention relates to the field of polymer chemistry and more particularly to encapsulated peptides and uses thereof.
    Type: Application
    Filed: November 16, 2009
    Publication date: June 3, 2010
    Applicants: UNIVERSITY OF SOUTH FLORIDA, INTEZYNE TECHNOLOGIES, INC.
    Inventors: CHUANHAI CAO, XIAOYANG LIN, KURT BREITENKAMP, HABIB SKAFF, KEVIN N. SILL