Abstract: Provided herein are conjugates comprising a protein and an oligosaccharide of one of Formulae I-VI. Also provided herein are pharmaceutical compositions comprising such conjugates. Further provided herein are methods of treating a lysosomal storage disorder in a mammal by administration of an oligosaccharide-glycoprotein conjugate.

Abstract: A method for scanning enhancement is provided. The method comprises receiving a channel scan request, including a scan channel number, a bandwidth, and a total scan time. The method further comprises determining a number of a plurality of scans based on the total scan time and an individual scan time for an AP. The method further comprises determining a plurality of offset values corresponding to the plurality of scans based on the number of the plurality of scans. In addition, the method further comprises performing off-channel scanning based on the scan channel number, the bandwidth, the number of the plurality of scans, and the plurality of offset values. Implementations of the present disclosure can improve the effect and the efficiency of the scanning process, the performance of the features of the upper layer, and the user experience.

Abstract: Techniques for performing a digital operation on a digital image are described along with methods and systems employing such techniques. According to the techniques, an input (e.g., an input stroke) is received by, for example, a processing system. Based upon the input, an area of the digital image upon which a digital operation (e.g., for removal of a distractor within the area) is to be performed is determined. In an implementation, one or more metrics of an input stroke are analyzed, typically in real time, to at least partially determine the area upon which the digital operation is to be performed. In an additional or alternative implementation, the input includes a first point, a second point and a connector, and the area is at least partially determined by a location of the first point relative to a location of the second point and/or by locations of the first point and/or second point relative to one or more edges of the digital image.

Abstract: Primers, a kit and a method for detecting African swine fever virus are provided, which relates to virus detection technologies. The primers are used to detect vp72 gene of African swine fever virus, and nucleotide sequences thereof are shown in SEQ ID NO: 6 and SEQ ID NO: 7. The kit includes the primers. The method uses the primers or the kit to perform dye fluorescence quantitative polymerase chain reaction (PCR) on genomic DNA of a sample to be detected. This method has strong specificity, high sensitivity, good reproducibility, and lower cost than the TaqMan probe method.

Abstract: A use of a canopy fibroblast growth factor signaling regulator 3 (CNPY3) protein as a target for treating of dengue fever is provided belongs to the technical field of antiviral drugs. An important host protein CNPY3 related to dengue virus infection is identified. A host gene is significantly down-regulated in blood of dengue patients and in dengue virus (DENV) infected dendritic cells and THP-1 cells. Its expression is negatively correlated with the progression of dengue disease and positively correlated with the expression of most Toll-like receptors. Down-regulation of the host gene inhibits the production of IFN-? and the expression of ISGs in THP-1 cells, promoting DENV-2 infection. Up-regulation of the host gene expression in Vero and HEK 293T cells inhibits DENV-2 infection. It indicates that CNPY3 participates in an innate immune response signaling pathway, has the effect of anti-dengue virus, and is a potential therapeutic target for dengue fever.

Abstract: A method for preparing a static/dynamic three-dimensional (3D) microcrack propagation sensor, a sensor and equipment, belongs to the field of sensor technology.