Abstract: A degradable biomedical magnesium alloy drug-eluting vascular stent and a preparation method. With the total weight of a magnesium alloy being 100% for calculation, the magnesium alloy comprises the following components in percentage by weight: 3.0-6.0% of Gd, 2.5-5.5% of Y, 1.0-3.0% of Li, 0.3-1.0% of Zn, 0.2-1.0% of Zr, and the balance being Mg. The stent has good radial support strength and strain dispersion capability by means of finite element design. After a protective coating is used, the corrosion resistance of the magnesium alloy stent is greatly improved. An arsenic trioxide/rapamycin and tacrolimus composite drug sustained-release system is used to fully adapt to the damage repair process of blood vessels. An implantation result of large animals shows that the vascular stent system has a good anti-restenosis treatment effect.

Abstract: The present disclosure provides a degradable corrosion-resistant high strength and ductility magnesium alloy for biomedical use and the preparation method therefor. With regard to a total weight of the magnesium alloy of 100%, the composition of components of the magnesium alloy comprises: 1.0 to 4.5% of Nd, 0.2 to 2.0% of Zn, 0 to 1.0% of Ca, 0 to 1.0% of Zr, and balance of Mg. The magnesium alloy is prepared by producing a magnesium alloy ingot by means of vacuum semi-continuous casting and according to the components and weight percentage thereof followed by solid solution treatment and extrusion. The degradable corrosion-resistant high strength and ductility magnesium alloy for biomedical use provided by the present disclosure has the advantages of being non-toxic and fully degradable, good corrosion resistance as well as high strength and ductility etc., and can be used for preparing a vascular stent.

Abstract: A composite anti-restenosis drug for use with a coronary drug-eluting stent, and a controlled release system for the drug. The composite drug comprises arsenic trioxide and rapamycin, which may be used in combination to prevent in-stent restenosis and reduce the incidence of intravascular thrombosis. The controlled release system for the composite drug may control the release of the composite drug so as to achieve the therapeutic effect of controlling restenosis and preventing the formation of thromboses.

Abstract: The present disclosure provides a degradable corrosion-resistant high strength and ductility magnesium alloy for biomedical use and the preparation method therefor. With regard to a total weight of the magnesium alloy of 100%, the composition of components of the magnesium alloy comprises: 1.0 to 4.5% of Nd, 0.2 to 2.0% of Zn, 0 to 1.0% of Ca, 0 to 1.0% of Zr, and balance of Mg. The magnesium alloy is prepared by producing a magnesium alloy ingot by means of vacuum semi-continuous casting and according to the components and weight percentage thereof followed by solid solution treatment and extrusion. The degradable corrosion-resistant high strength and ductility magnesium alloy for biomedical use provided by the present disclosure has the advantages of being non-toxic and fully degradable, good corrosion resistance as well as high strength and ductility etc., and can be used for preparing a vascular stent.

Abstract: An arsenic trioxide medical elution scaffold and preparation method thereof, wherein the arsenic trioxide medical elution scaffold comprises scaffold, polymer coating covering the scaffold and arsenic trioxide loaded in the polymer coating which is in the form of single particle or particle conglomeration island. Animal experiments testify that the medical release of the arsenic trioxide medical elution scaffold is suitably uniform, and can be controlled to meet clinic requirement.

Abstract: An electrophysiology ablation device includes a catheter sleeve (1), an electrode sleeve (2), a steering ball sleeve (4), a central rod (6), an ablation electrode (3) and a steering ball (5). The catheter sleeve (1), the electrode sleeve (2), the steering ball sleeve (4) and the central rod (6) are muff-coupled together, and the steering ball (5) can be deployed radially to define a meshed spherical shape, in order to steer the positioning of the ablation electrode (3) which can be deployed to define a meshed disk shape, so the ablation electrode (3) can be positioned at the ostium of the pulmonary vein accurately.

Abstract: An electrophysiology ablation device includes a catheter sleeve (1), an electrode sleeve (2), a steering ball sleeve (4), a central rod (6), an ablation electrode (3) and a steering ball (5). The catheter sleeve (1), the electrode sleeve (2), the steering ball sleeve (4) and the central rod (6) are muff-coupled together, and the steering ball (5) can be deployed radially to define a meshed spherical shape, in order to steer the positioning of the ablation electrode (3) which can be deployed to define a meshed disk shape, so the ablation electrode (3) can be positioned at the ostium of the pulmonary vein accurately.

Abstract: An arsenic trioxide medical elution scaffold and preparation method thereof, wherein the arsenic trioxide medical elution scaffold comprises scaffold, polymer coating covering the scaffold and arsenic trioxide loaded in the polymer coating which is in the form of single particle or particle conglomeration island. Animal experiments testify that the medical release of the arsenic trioxide medical elution scaffold is suitably uniform, and can be controlled to meet clinic requirement.