Patents by Inventor Xiaoying Chen

Xiaoying Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Design of Spacers To Increase The Expression of Recombinant Fusion Proteins
    Publication number: 20110288269
    Abstract: The present invention relates to fusion proteins. The invention specifically relates to compositions and methods of Tf-based fusion proteins that demonstrate a high-level expression of transferrin (Tf)-based fusion proteins by inserting a helical linker between two protein domains.
    Type: Application
    Filed: April 25, 2011
    Publication date: November 24, 2011
    Applicant: UNIVERSITY OF SOUTHERN CALIFORNIA
    Inventors: Wei-Chiang SHEN, Nurmamet AMET, Xiaoying CHEN, Hsin-Fang LEE
  • Spacers to increase the expression of recombinant fusion proteins
    Patent number: 7943733
    Abstract: The present invention relates to fusion proteins. The invention specifically relates to compositions and methods of Tf-based fusion proteins that demonstrate a high-level expression of transferrin (Tf)-based fusion proteins by inserting a helical linker between two protein domains.
    Type: Grant
    Filed: December 19, 2008
    Date of Patent: May 17, 2011
    Assignee: University of Southern California
    Inventors: Wei-Chiang Shen, Nurmamet Amet, Xiaoying Chen, Hsin-Fang Lee
  • SPACERS TO INCREASE THE EXPRESSION OF RECOMBINANT FUSION PROTEINS
    Publication number: 20090170163
    Abstract: The present invention relates to fusion proteins. The invention specifically relates to compositions and methods of Tf-based fusion proteins that demonstrate a high-level expression of transferrin (Tf)-based fusion proteins by inserting a helical linker between two protein domains.
    Type: Application
    Filed: December 19, 2008
    Publication date: July 2, 2009
    Applicant: University of Southern California
    Inventors: Wei-Chiang Shen, Nurmamet Amet, Xiaoying Chen, Hsin-Fang Lee
  • Di-aryl ethers and their derivatives as anti-cancer agents
    Patent number: 6169104
    Abstract: The present invention relates, inter alia, to compounds that bind tubulin and exhibit anti-mitotic properties and to methods of using such compounds to inhibit abnormal cell mitosis and, in particular, to inhibit tumor cell growth. In addition, methods are presented of treating mammalian diseases associated with undesired and uncontrolled angiogenesis.
    Type: Grant
    Filed: March 25, 1998
    Date of Patent: January 2, 2001
    Assignees: Large Scale Biology Corporation, SRI International
    Inventors: Daniel Tus{acute over (e)}, Xiaoying Chen, Charles K. Hiebert, Cris M. Olsen, Keith Laderoute, Nahid Waleh, A. Merrill Knapp
  • Modification of DNA and oligonucleotides using metal complexes of polyaza ligands
    Patent number: 5504075
    Abstract: A process is provided for oxidatively modifying nucleic acids containing a target nucleotide. The nucleic acid is contacted with a polyaza metal complex in the presence of an oxidizing agent so that the nucleic acid is modified at or near the target nucleotide. Also provided are a kit for carrying out the process and a method for treating neoplastic growth by administering to a subject having neoplastic growth, an effective amount of a polyaza metal complex which is capable of modifying DNA.
    Type: Grant
    Filed: September 28, 1993
    Date of Patent: April 2, 1996
    Assignee: The Research Foundation of State University of New York
    Inventors: Cynthia J. Burrows, Steven E. Rokita, Xiaoying Chen
  • Modification of DNA and oligonucleotides using metal complexes of polyaza ligands
    Patent number: 5272056
    Type: Grant
    Filed: January 3, 1991
    Date of Patent: December 21, 1993
    Assignee: The Research Foundation of State University of New York
    Inventors: Cynthia J. Burrows, Steven E. Rokita, Xiaoying Chen